Phosphoglycerate mutase
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| phosphoglycerate mutase 1 (brain)
| |
| Identifiers | |
| Symbol | PGAM1 |
| Alt. Symbols | PGAMA |
| Entrez | 5223 |
| HUGO | 8888 |
| OMIM | 172250 |
| RefSeq | NM_002629 |
| UniProt | P18669 |
| Other data | |
| EC number | 5.4.2.1 |
| Locus | Chr. 10 q25.3 |
| phosphoglycerate mutase 2 (muscle)
| |
| Identifiers | |
| Symbol | PGAM2 |
| Entrez | 5224 |
| HUGO | 8889 |
| OMIM | 261670 |
| RefSeq | NM_000290 |
| UniProt | P15259 |
| Other data | |
| EC number | 5.4.2.1 |
| Locus | Chr. 7 p13-p12 |
Phosphoglycerate mutase (PGM) is an enzyme that catalyzes step 8 of glycolysis. It catalyzes the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG).
Glycerate 3-phosphate.svg
|
This enzyme is not to be confused with Bisphosphoglycerate mutase which catalyzes the conversion of 1,3-bisphosphoglycerate to 2,3-bisphosphoglycerate.
External links
Template:Metabolic pathway stub
Carbohydrate metabolism: glycolysis/gluconeogenesis enzymes | |
|---|---|
| Glycolysis | Glucokinase/Hexokinase/Glucose 6-phosphatase - Glucose isomerase - Phosphofructokinase 1/Fructose 1,6-bisphosphatase - Aldolase - Triosephosphate isomerase - Glyceraldehyde 3-phosphate dehydrogenase - Phosphoglycerate kinase - Phosphoglycerate mutase - Enolase - Pyruvate kinase |
| Gluconeogenesis only | Pyruvate carboxylase - Phosphoenolpyruvate carboxykinase - from lactate (Cori cycle): Lactate dehydrogenase - from alanine (Alanine cycle): Alanine transaminase |
| Regulatory | Phosphofructokinase 2/Fructose 2,6-bisphosphatase - Bisphosphoglycerate mutase |
Isomerase: mutases (EC 5.4) | |
|---|---|
| 5.4.2 Phosphomutases | Phosphoglycerate mutase - Bisphosphoglycerate mutase - Phosphoglucomutase |
| 5.4.99 Other groups | Methylmalonyl-CoA mutase - Lanosterol synthase |
