Phosphoglycerate mutase

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phosphoglycerate mutase 1 (brain)
Identifiers
Symbol	PGAM1
Alt. Symbols	PGAMA
Entrez	5223
HUGO	8888
OMIM	172250
RefSeq	NM_002629
UniProt	P18669
Other data
EC number	5.4.2.1
Locus	Chr. 10 q25.3

phosphoglycerate mutase 2 (muscle)
Identifiers
Symbol	PGAM2
Entrez	5224
HUGO	8889
OMIM	261670
RefSeq	NM_000290
UniProt	P15259
Other data
EC number	5.4.2.1
Locus	Chr. 7 p13-p12

Phosphoglycerate mutase (PGM) is an enzyme that catalyzes step 8 of glycolysis. It catalyzes the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG).

Glycerate 3-phosphate.svg

3PG
2PG

This enzyme is not to be confused with Bisphosphoglycerate mutase which catalyzes the conversion of 1,3-bisphosphoglycerate to 2,3-bisphosphoglycerate.

External links

MeSH Phosphoglycerate+Mutase

Template:Metabolic pathway stub

v • d • e Carbohydrate metabolism: glycolysis/gluconeogenesis enzymes
Glycolysis	Glucokinase/Hexokinase/Glucose 6-phosphatase - Glucose isomerase - Phosphofructokinase 1/Fructose 1,6-bisphosphatase - Aldolase - Triosephosphate isomerase - Glyceraldehyde 3-phosphate dehydrogenase - Phosphoglycerate kinase - Phosphoglycerate mutase - Enolase - Pyruvate kinase
Gluconeogenesis only	Pyruvate carboxylase - Phosphoenolpyruvate carboxykinase - from lactate (Cori cycle): Lactate dehydrogenase - from alanine (Alanine cycle): Alanine transaminase
Regulatory	Phosphofructokinase 2/Fructose 2,6-bisphosphatase - Bisphosphoglycerate mutase

v • d • e Isomerase: mutases (EC 5.4)
5.4.2 Phosphomutases	Phosphoglycerate mutase - Bisphosphoglycerate mutase - Phosphoglucomutase
5.4.99 Other groups	Methylmalonyl-CoA mutase - Lanosterol synthase