Leg pain is a common non-specific symptom that often has a musculoskeletal, metabolic or drug side effect basis.
| Cardiovascular
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Aortoiliac occlusive disease, Cholesterol Emboli Syndrome, Deep Vein Thrombosis, Peripheral Arterial Disease, Thrombophlebitis, Varicose veins
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| Chemical / poisoning
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No underlying causes
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| Dermatologic
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Behcet's disease
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| Drug Side Effect
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Abatacept Injection, Acebutolol, Acitretin, Aldesleukin, Alendronate, Allopurinol, Amikacin Sulfate Injection, Anagrelide, Anastrozole, Aripiprazole, Atazanavir, Atenolol, Atorvastatin, Bevacizumab Injection, Bortezomib, Buspirone, Capecitabine, Celecoxib, Celiac disease, Clofarabine Injection, Clonazepam, Clopidogrel, Cortisol, Darbepoetin Alfa, Docetaxel, Epoetin Alfa Injection, Ethacrynic Acid, Etidronate, Ezetimibe, Fenofibrate, Filgrastim, Fluvastatin, Gabapentin, Galantamine, Glatiramer Injection, Ibandronate, Iloprost, Imatinib, Infliximab Injection, Interferon Alfa-2a and Alfa-2b Injection, Interferon Alfacon-1 Injection, Interferon beta-1a Intramuscular Injection, Interferon Beta-1b Injection, Interferon Gamma-1b Injection, Lamivudine, Latanoprost, Leflunomide, Letrozole, Leuprolide, Lovastatin, Methimazole, Methylergonovine, Methylprednisolone, Mifepristone, Natalizumab injection , Ofloxacin , Paclitaxel, Peginterferon alfa-2a, Prednisone, Pyrazinamide, Quinupristin dalfopristin, Ribavirin, Rofecoxib, Rosiglitazone, Rosuvastatin, Sunitinib , Tadalafil , Tamsulosin , Telbivudine , Temozolomide , Terbutaline, Teriparatide, Tiotropium, Torsemide, Valganciclovir, Valsartan, Vancomycin, Vinblastine, Vincristine, Zalcitabine, Ziprasidone, Zolmitriptan, Zolpidem,
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| Ear Nose Throat
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No underlying causes
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| Endocrine
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Hyperparathyroidism, Primary hyperparathyroidism
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| Environmental
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No underlying causes
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| Gastroenterologic
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Ulcerative colitis
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| Genetic
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Fairbanks disease, Familial Mediterranean fever, Mitochondrial trifunctional protein deficiency, Osteogenesis imperfecta, Hereditary multiple exostoses, Recessive multiple epiphyseal dysplasia, Farber disease
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| Hematologic
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Erdheim-Chester disease, Leukemia, Lymphangiomatosis, Multiple myeloma, Phlebitis, Phlegmasia cerulea dolens, Thrombocytosis, Acute lymphoblastic leukemia, Acute myeloid leukemia, Acute promyelocytic leukemia, Cholesterol Embolism
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| Iatrogenic
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No underlying causes
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| Infectious Disease
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Bacterial : Cellulitis, Q Fever, Lassa Fever, Lemierre's Syndrome, Leptospirosis
Viral : Parvovirus B19, Poliomyelitis, Rocky Mountain spotted fever, Acquired Immune Deficiency Syndrome, Coxsackie B,
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| Musculoskeletal / Ortho
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Athlete's foot, Baker's cyst, Bone tumor, Buerger's disease, Chondroblastoma, Chondromalacia patellae, Chondrosarcoma, Gout, Hereditary multiple exostoses, Ledderhose's disease, Legg-Calve-Perthes syndrome, Morton's toe, Myofascial Pain Syndrome, Myositis ossificans, Osteochondrosis, Paget's disease of bone, Pes anserinus, Pigmented villonodular synovitis, Prepatellar bursitis, Recessive multiple epiphyseal dysplasia, Retropatellar Pain Syndrome, Sciatica, Synovial osteochondromatosis, Tenosynovitis, Erythromelagia, Ewing's sarcoma, Giant cell tumor of bone, Osteoporosis, Still's disease, Fairbanks disease, Osteogenesis imperfecta
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| Neurologic
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Amyotrophic Lateral Sclerosis, Anterior spinal artery syndrome, Erythromelagia, Meralgia paraesthetica, Peripheral Neuropathy, Restless Leg Syndrome
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| Nutritional / Metabolic
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Acute Intermittent Porphyria, Farber disease, Glycogen storage disease type V, Hypercalcemia, Mucopolysaccharidosis, Osteomalacia
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| Obstetric/Gynecologic
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No underlying causes
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| Oncologic
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Acute lymphoblastic leukemia, Acute myeloid leukemia, Acute promyelocytic leukemia, Ewing's sarcoma, Giant cell tumor of bone, Osteochondroma, Osteoma, Osteosarcoma, Leukemia, Lymphangiomatosis, Chondroblastoma, Chondrosarcoma
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| Opthalmologic
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Behect's disease
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| Overdose / Toxicity
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No underlying causes
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| Psychiatric
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Pain disorder
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| Pulmonary
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No underlying causes
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| Renal / Electrolyte
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Hypercalcemia, Hypocalcemia, Hypokalemia, Hyponatremia
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| Rheum / Immune / Allergy
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Rheumatology : Ankylosing Spondylitis, Behcet's disease, Caplan's Syndrome, Fibromyalgia, Osteoarthritis, Osteoporosis, Polymyalgia Rheumatica, Rheumatoid arthritis, Still's disease, Gout
Immunology : Systemic lupus erythematosus, Ulcerative colitis, Vasculitis, Graft-versus-host disease, Familial Mediterranean fever
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| Sexual
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No underlying causes
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| Trauma
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No underlying causes
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| Urologic
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No underlying causes
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| Dental
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No underlying causes
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| Miscellaneous
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Phantom pain
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