Phantom pain

Phantom pain

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Overview

Phantom pain, also called deafferentation pain, anesthesia dolorosa, or denervation pain, is pain that is felt in a part of the body (usually an extremity) that either no longer exists due to amputation or is insensate as a result of nerve severance. It is often described as a burning sensation, though individual accounts vary. This pain does not originate from the limb itself, as such would be impossible in these cases, but is instead the result of the brain receiving messages from the spinal cord which it interprets as pain coming from the affected limb.

Physiology

Pain usually begins when nerve endings relay information to nerves, which in turn relay it to ganglia just outside the spinal vertebrae, which send it to nociceptive (pain-sensing) neurons inside the spinal cord, which finally send the information to the brain. If the nociceptive neurons cease to receive information to pass on, they will instead send the neurological equivalent of white noise, which the brain then interprets as pain.

In cases in which a traumatic event causes nerve severance and also detaches the nociceptive neurons from the rest of the spinal cord, phantom pain will not develop. Some patients who do not receive adequate relief from nerve blocks, narcotic painkillers, or other methods of pain management may undergo a procedure called dorsal root entry zone (DREZ) lesioning. DREZ lesioning is a form of neurosurgery in which the wayward nociceptive neurons are destroyed.

See also

• Phantom eye syndrome
• Phantom limb

External links

• Information about Phantom Pain from The UMC St Radboud amputee website

Cost Effectiveness of Phantom pain

| group5 = Clinical Trials Involving Phantom pain | list5 = Ongoing Trials on Phantom pain at Clinical Trials.gov • Trial results on Phantom pain • Clinical Trials on Phantom pain at Google

| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Phantom pain | list6 = US National Guidelines Clearinghouse on Phantom pain • NICE Guidance on Phantom pain • NHS PRODIGY Guidance • FDA on Phantom pain • CDC on Phantom pain

| group7 = Textbook Information on Phantom pain | list7 = Books and Textbook Information on Phantom pain

| group8 = Pharmacology Resources on Phantom pain | list8 = AND (Dose)}} Dosing of Phantom pain • AND (drug interactions)}} Drug interactions with Phantom pain • AND (side effects)}} Side effects of Phantom pain • AND (Allergy)}} Allergic reactions to Phantom pain • AND (overdose)}} Overdose information on Phantom pain • AND (carcinogenicity)}} Carcinogenicity information on Phantom pain • AND (pregnancy)}} Phantom pain in pregnancy • AND (pharmacokinetics)}} Pharmacokinetics of Phantom pain •

| group9 = Genetics, Pharmacogenomics, and Proteinomics of Phantom pain | list9 = AND (pharmacogenomics)}} Genetics of Phantom pain • AND (pharmacogenomics)}} Pharmacogenomics of Phantom pain • AND (proteomics)}} Proteomics of Phantom pain

| group10 = Newstories on Phantom pain | list10 = Phantom pain in the news • Be alerted to news on Phantom pain • News trends on Phantom pain</small>

| group11 = Commentary on Phantom pain | list11 = Blogs on Phantom pain

| group12 = Patient Resources on Phantom pain | list12 = Patient resources on Phantom pain • Discussion groups on Phantom pain • Patient Handouts on Phantom pain • Directions to Hospitals Treating Phantom pain • Risk calculators and risk factors for Phantom pain

| group13 = Healthcare Provider Resources on Phantom pain | list13 = Symptoms of Phantom pain • Causes & Risk Factors for Phantom pain • Diagnostic studies for Phantom pain • Treatment of Phantom pain

| group14 = Continuing Medical Education (CME) Programs on Phantom pain | list14 = CME Programs on Phantom pain

| group15 = International Resources on Phantom pain | list15 = Phantom pain en Espanol • Phantom pain en Francais

| group16 = Business Resources on Phantom pain | list16 = Phantom pain in the Marketplace • Patents on Phantom pain

| group17 = Informatics Resources on Phantom pain | list17 = List of terms related to Phantom pain

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