Methimazole (patient information)

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Drug information courtesy of the National Library of Medicine Please visit the NLM website for the most current information.

For Overdosage Contact Poison Control at 1-800-222-1222 Immediately Report an adverse event using MedWatch Search for drug-drug interactions.

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Why this medication is prescribed

Methimazole is used to treat hyperthyroidism, a condition that occurs when the thyroid gland produces too much thyroid hormone. It is also taken before thyroid surgery or radioactive iodine therapy.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How this medication should be used

Methimazole comes as a tablet and usually is taken three times a day, approximately every 8 hours, with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Special precautions

Before taking methimazole:

• tell your doctor and pharmacist if you are allergic to methimazol, lactose, or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially anticoagulants ('blood thinners') such as warfarin (Coumadin), beta blockers such as propranolol (Inderal), diabetes medications, digoxin (Lanoxin), theophylline (Theobid, Theo-Dur), and vitamins.
• tell your doctor if you have or have ever had any blood disease, such as decreased white blood cells (leukopenia), decreased platelets (thrombocytopenia), or aplastic anemia, or liver disease (hepatitis, jaundice).
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Methimazole should not be used during pregnancy or breast-feeding. If you become pregnant while taking methimazole, call your doctor immediately. Methimazole may harm the fetus.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking methimazole.

Special dietary instructions

Methimazole may cause an upset stomach. Take methimazole with food or milk.

What to do if you forget a dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule at evenly spaced, 8-hour intervals. Do not take a double dose to make up for a missed one.

Side effects

Minor side effects

Methimazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• skin rash
• itching
• abnormal hair loss
• upset stomach
• vomiting
• loss of taste
• abnormal sensations (tingling, prickling, burning, tightness, and pulling)
• swelling
• joint and muscle pain
• drowsiness
• dizziness
• decreased white blood cells
• decreased platelets

Severe side effects

If you experience any of the following symptoms, call your doctor immediately:

• sore throat
• fever
• headache
• chills
• unusual bleeding or bruising
• right-sided abdominal pain with decreased appetite
• yellowing of the skin or eyes
• skin eruptions

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

Storage conditions needed for this medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Other information

Keep all appointments with your doctor and the laboratory.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names

• Tapazole®

v • d • e WikiDoc Research Resources for Methimazole (patient information)
Articles on Methimazole (patient information)	Most recent articles on Methimazole (patient information) • Most cited articles on Methimazole (patient information) • Review articles on Methimazole (patient information) • Articles on Methimazole (patient information) in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Methimazole (patient information)	Powerpoint slides on Methimazole (patient information) • Images of Methimazole (patient information) • Photos of Methimazole (patient information) • Podcasts & MP3s on Methimazole (patient information) • Videos on Methimazole (patient information)
Evidence Based Medicine Regarding Methimazole (patient information)	Cochrane Collaboration on Methimazole (patient information) • Bandolier on Methimazole (patient information) • TRIP on Methimazole (patient information)
Cost Effectiveness of Methimazole (patient information)	Cost Effectiveness of Methimazole (patient information)
Clinical Trials Involving Methimazole (patient information)	Ongoing Trials on Methimazole (patient information) at Clinical Trials.gov • Trial results on Methimazole (patient information) • Clinical Trials on Methimazole (patient information) at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Methimazole (patient information)	US National Guidelines Clearinghouse on Methimazole (patient information) • NICE Guidance on Methimazole (patient information) • NHS PRODIGY Guidance • FDA on Methimazole (patient information) • CDC on Methimazole (patient information)
Textbook Information on Methimazole (patient information)	Books and Textbook Information on Methimazole (patient information)
Pharmacology Resources on Methimazole (patient information)	Dosing of Methimazole (patient information) • Drug interactions with Methimazole (patient information) • Side effects of Methimazole (patient information) • Allergic reactions to Methimazole (patient information) • Overdose information on Methimazole (patient information) • Carcinogenicity information on Methimazole (patient information) • Methimazole (patient information) in pregnancy • Pharmacokinetics of Methimazole (patient information) •
Genetics, Pharmacogenomics, and Proteinomics of Methimazole (patient information)	Genetics of Methimazole (patient information) • Pharmacogenomics of Methimazole (patient information) • Proteomics of Methimazole (patient information)
Newstories on Methimazole (patient information)	Methimazole (patient information) in the news • Be alerted to news on Methimazole (patient information) • News trends on Methimazole (patient information)
Commentary on Methimazole (patient information)	Blogs on Methimazole (patient information)
Patient Resources on Methimazole (patient information)	Patient resources on Methimazole (patient information) • Discussion groups on Methimazole (patient information) • Patient Handouts on Methimazole (patient information) • Directions to Hospitals Treating Methimazole (patient information) • Risk calculators and risk factors for Methimazole (patient information)
Healthcare Provider Resources on Methimazole (patient information)	Symptoms of Methimazole (patient information) • Causes & Risk Factors for Methimazole (patient information) • Diagnostic studies for Methimazole (patient information) • Treatment of Methimazole (patient information)
Continuing Medical Education (CME) Programs on Methimazole (patient information)	CME Programs on Methimazole (patient information)
International Resources on Methimazole (patient information)	Methimazole (patient information) en Espanol • Methimazole (patient information) en Francais
Business Resources on Methimazole (patient information)	Methimazole (patient information) in the Marketplace • Patents on Methimazole (patient information)
Informatics Resources on Methimazole (patient information)	List of terms related to Methimazole (patient information)