Interstitial lung disease
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| Interstitial lung disease Classification and external resources | |
 | |
|---|---|
| End-stage pulmonary fibrosis of unknown origin, taken from an autopsy in the 1980s. | |
| ICD-10 | J84.9 |
| ICD-9 | 506.4, 508.1, 515, 516.3, 714.81, 770.7 |
| DiseasesDB | 31509 |
| eMedicine | ped/1950 |
| MeSH | D017563 |
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Introduction
Interstitial lung disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a group of lung diseases (including idiopathic pulmonary fibrosis), affecting the alveolar epithelium, pulmonary capillary endothelium, basement membrane, perivascular and perilymphatic tissues. The term ILD is used to distinguish these diseases from obstructive airways diseases. Most types of ILD involve fibrosis, but this is not essential; indeed fibrosis is often a later feature. Hence the term pulmonary fibrosis has fallen out of favor.
Causes
ILD may be classified according to the cause: -
- Inhaled substances
- Inorganic
- Organic
- Drug induced
- Connective tissue disease
- Infection
- Atypical pneumonia
- Pneumocystis pneumonia (PCP)
- Tuberculosis
- Idiopathic
- Malignancy
- Lymphangitic carcinomatosis
Investigation
Investigation is tailored towards the symptoms and signs. Most patients have blood testing, chest x-ray, pulmonary function testing, and high resolution CT thorax.
Treatment
ILD is not a single disease, but encompasses many different pathological processes. Hence treatment is different for each disease.
If a specific occupational exposure cause is found, the person should avoid that environment. If a drug cause is suspected, that drug should be discontinued.
Many idiopathic and connective tissue-based causes of ILD are treated with prednisolone. Some patients respond to immunosuppressant treatment. Patients with hypoxemia may be given supplemental oxygen.
External links
- Coalition for Pulmonary Fibrosis - Research, Education, Support & Hope
- What is Pulmonary Fibrosis?
- 00736 at CHORUS
- 1476788304 at GPnotebook
- MeSH Pulmonary+Fibrosis
- MedlinePlus Overview pulmonaryfibrosis
- AIMIP - Italian Association for IPF - Associazione Italiana
- Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases
- University of Chicago Interstitial Lung Disease Program
- PA-IPF - The Pennsylvania Idiopathic Pulmonary Fibrosis State Registry
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
