Antiplatelet drug

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WikiDoc Resources for Antiplatelet drug
Articles
Most recent articles on Antiplatelet drug Most cited articles on Antiplatelet drug Review articles on Antiplatelet drug Articles on Antiplatelet drug in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Antiplatelet drug Images of Antiplatelet drug Photos of Antiplatelet drug Podcasts & MP3s on Antiplatelet drug Videos on Antiplatelet drug
Evidence Based Medicine
Cochrane Collaboration on Antiplatelet drug Bandolier on Antiplatelet drug TRIP on Antiplatelet drug
Clinical Trials
Ongoing Trials on Antiplatelet drug at Clinical Trials.gov Trial results on Antiplatelet drug Clinical Trials on Antiplatelet drug at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Antiplatelet drug NICE Guidance on Antiplatelet drug NHS PRODIGY Guidance FDA on Antiplatelet drug CDC on Antiplatelet drug
Books
Books on Antiplatelet drug
News
Antiplatelet drug in the news Be alerted to news on Antiplatelet drug News trends on Antiplatelet drug
Commentary
Blogs on Antiplatelet drug
Definitions
Definitions of Antiplatelet drug
Patient Resources / Community
Patient resources on Antiplatelet drug Discussion groups on Antiplatelet drug Patient Handouts on Antiplatelet drug Directions to Hospitals Treating Antiplatelet drug Risk calculators and risk factors for Antiplatelet drug
Healthcare Provider Resources
Symptoms of Antiplatelet drug Causes & Risk Factors for Antiplatelet drug Diagnostic studies for Antiplatelet drug Treatment of Antiplatelet drug
Continuing Medical Education (CME)
CME Programs on Antiplatelet drug
International
Antiplatelet drug en Espanol Antiplatelet drug en Francais
Business
Antiplatelet drug in the Marketplace Patents on Antiplatelet drug
Experimental / Informatics
List of terms related to Antiplatelet drug

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Overview

An antiplatelet drug is a member of a class of pharmaceuticals that decreases platelet aggregation and inhibits thrombus formation. They are effective in the arterial circulation, where anticoagulants have little effect.

They are widely used in primary and secondary prevention of thrombotic cerebrovascular or cardiovascular disease.

The Most Important Antiplatelet Drugs

• COX-2 inhibitor / Cyclooxygenase inhibitors
  • Aspirin
• Adenosine diphosphate (ADP) receptor inhibitors
  • Clopidogrel (Plavix)
  • Ticlopidine (Ticlid)
• Phosphodiesterase inhibitors
  • Cilostazol (Pletal)
• Glycoprotein IIB/IIIA inhibitors (intravenous use only)
  • Abciximab (ReoPro)
  • Eptifibatide (Integrilin)
  • Tirofiban (Aggrastat)
  • Defibrotide
• Adenosine reuptake inhibitors
  • Dipyridamole (Persantine)

See also

• Anticoagulant drug
• Thrombolytic drug
• Antiaggregants

v • d • e Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)
Antiplatelet drugs	Glycoprotein IIb/IIIa inhibitors Abciximab • Eptifibatide • Tirofiban ADP receptor/P2Y12 inhibitors (Thienopyridines) Clopidogrel • Ticlopidine • Prasugrel Prostaglandin analogue (PGI2) Beraprost • Prostacyclin • Iloprost • Treprostinil COX inhibitors Acetylsalicylic acid/Aspirin # • Aloxiprin • Carbasalate calcium Other Ditazole • Cloricromen • Dipyridamole • Indobufen • Picotamide • Triflusal
Anticoagulants	Vitamin K antagonists (inhibit II, VII, IX, X) coumarins: Acenocoumarol • Coumatetralyl • Dicoumarol (Dicumarol) • Ethyl biscoumacetate • Phenprocoumon • Warfarin 1,3-indandiones: Clorindione • Diphenadione • Phenindione other: Tioclomarol Factor Xa inhibitors (with some II inhibition) Heparin group/ glycosaminoglycans/ (bind antithrombin) low molecular weight heparin (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) oligosaccharides (Fondaparinux, Idraparinux) heparinoid (Danaparoid, Sulodexide, Dermatan sulfate) Direct factor Xa inhibitors xabans (Apixaban, Otamixaban, Rivaroxaban) Direct thrombin (II) inhibitors bivalent: Hirudin (Bivalirudin, Lepirudin, Desirudin) univalent: Argatroban • Dabigatran • Melagatran • Ximelagatran Other Defibrotide • Ramatroban • Antithrombin III • Protein C (Drotrecogin alfa)
Thrombolytic drugs/ fibrinolytics	plasminogen activators: TPA (Alteplase, Reteplase, Tenecteplase) • UPA (Urokinase, Saruplase) • Streptokinase # • Anistreplase • Monteplase other serine endopeptidases: Ancrod • Fibrinolysin Brinase
Non-medicinal	Citrate • EDTA • Oxalate
# = WHO-EM

v • d • e Major Drug Groups
Gastrointestinal tract (A)	Antacids • Antiemetics  • H₂-receptor antagonists • Proton pump inhibitors • Laxatives • Antidiarrhoeals
Blood and blood forming organs (B)	Anticoagulants • Antiplatelets • Thrombolytics
Cardiovascular system (C)	Antiarrhythmics • Antihypertensives • Diuretics • Vasodilators • Antianginals • Beta blockers • Angiotensin converting enzyme inhibitors • Antihyperlipidemics
Skin (D)	Emollients - Antipruritics
Reproductive system (G)	Hormonal contraception • Fertility agents • Selective estrogen receptor modulators • Sex hormones
Endocrine system (H)	Anti-diabetics • Corticosteroids • Sex hormones • Thyroid hormones
Infections and Infestations (J, P)	Antibiotics • Antivirals • Vaccines • Antifungals • Antiprotozoals • Anthelmintics
Malignant and Immune disease (L)	Anticancer agents • Immunostimulators • Immunosuppressants
Muscles, Bones, and Joints (M)	Anabolic steroids • Anti-inflammatories • Antirheumatics • Corticosteroids • Muscle relaxants
Brain and Nervous system (N)	Anesthetics • Analgesics • Anticonvulsants • Mood stabilizers  • Anxiolytics • Antipsychotics • Antidepressants • Nervous system stimulants • Sedatives
Respiratory system (R)	Bronchodilators • Decongestants  • Antihistamines

v • d • e WikiDoc Research Resources for Antiplatelet drug
Articles on Antiplatelet drug	Most recent articles on Antiplatelet drug • Most cited articles on Antiplatelet drug • Review articles on Antiplatelet drug • Articles on Antiplatelet drug in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Antiplatelet drug	Powerpoint slides on Antiplatelet drug • Images of Antiplatelet drug • Photos of Antiplatelet drug • Podcasts & MP3s on Antiplatelet drug • Videos on Antiplatelet drug
Evidence Based Medicine Regarding Antiplatelet drug	Cochrane Collaboration on Antiplatelet drug • Bandolier on Antiplatelet drug • TRIP on Antiplatelet drug
Cost Effectiveness of Antiplatelet drug	Cost Effectiveness of Antiplatelet drug
Clinical Trials Involving Antiplatelet drug	Ongoing Trials on Antiplatelet drug at Clinical Trials.gov • Trial results on Antiplatelet drug • Clinical Trials on Antiplatelet drug at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Antiplatelet drug	US National Guidelines Clearinghouse on Antiplatelet drug • NICE Guidance on Antiplatelet drug • NHS PRODIGY Guidance • FDA on Antiplatelet drug • CDC on Antiplatelet drug
Textbook Information on Antiplatelet drug	Books and Textbook Information on Antiplatelet drug
Pharmacology Resources on Antiplatelet drug	Dosing of Antiplatelet drug • Drug interactions with Antiplatelet drug • Side effects of Antiplatelet drug • Allergic reactions to Antiplatelet drug • Overdose information on Antiplatelet drug • Carcinogenicity information on Antiplatelet drug • Antiplatelet drug in pregnancy • Pharmacokinetics of Antiplatelet drug •
Genetics, Pharmacogenomics, and Proteinomics of Antiplatelet drug	Genetics of Antiplatelet drug • Pharmacogenomics of Antiplatelet drug • Proteomics of Antiplatelet drug
Newstories on Antiplatelet drug	Antiplatelet drug in the news • Be alerted to news on Antiplatelet drug • News trends on Antiplatelet drug
Commentary on Antiplatelet drug	Blogs on Antiplatelet drug
Patient Resources on Antiplatelet drug	Patient resources on Antiplatelet drug • Discussion groups on Antiplatelet drug • Patient Handouts on Antiplatelet drug • Directions to Hospitals Treating Antiplatelet drug • Risk calculators and risk factors for Antiplatelet drug
Healthcare Provider Resources on Antiplatelet drug	Symptoms of Antiplatelet drug • Causes & Risk Factors for Antiplatelet drug • Diagnostic studies for Antiplatelet drug • Treatment of Antiplatelet drug
Continuing Medical Education (CME) Programs on Antiplatelet drug	CME Programs on Antiplatelet drug
International Resources on Antiplatelet drug	Antiplatelet drug en Espanol • Antiplatelet drug en Francais
Business Resources on Antiplatelet drug	Antiplatelet drug in the Marketplace • Patents on Antiplatelet drug
Informatics Resources on Antiplatelet drug	List of terms related to Antiplatelet drug