Prostaglandin analogue
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Synthetic prostaglandin analogues are molecules which are manufactured to bind to a prostaglandin receptor.
Wider use of prostaglandin analogues is limited by unwanted side effects and their abortive potential.
Uses
- Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. They exert antisecretory and cytoprotective properties and are especially indicated for the elderly on continuous doses of NSAIDs.
- Prostaglandin analogues can also be used in the management of open-angle glaucoma. They reduce intra-ocular pressure by enhancing uveoscleral outflow and may also have some effect on the trabecular meshwork as well. Latanoprost, travoprost, unoprostone and bimatoprost are examples of prostaglandin analogues used in the management of open-angle glaucoma.
External links
Drugs for acid related disorders: Drugs for peptic ulcer and GERD/GORD (A02B) | |
|---|---|
| H2 antagonists | Cimetidine, Famotidine, Nizatidine, Ranitidine, Roxatidine |
| Prostaglandins/analogues | Misoprostol, Enprostil |
| Proton pump inhibitors | Esomeprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole, Tenatoprazole |
| Other | Carbenoxolone, Sucralfate, Pirenzepine |
Ophthalmologicals: antiglaucoma preparations and miotics (S01E) | |
|---|---|
| Sympathomimetics | Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine |
| Parasympathomimetics | Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine |
| Carbonic anhydrase inhibitors | Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide |
| Beta blocking agents | Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol |
| Prostaglandin analogues | Bimatoprost • Latanoprost • Travoprost • Unoprostone |
| Other agents | Dapiprazole • Guanethidine |
Eicosanoids: prostaglandins | |
|---|---|
| Endogenous/series 2 | D2 - E2 (Dinoprostone) - F2 (Dinoprost) - H2 - I2 (Prostacyclin) |
| Prostaglandin analogues | E: Alprostadil - Enprostil - Misoprostol
F: Bimatoprost - Carboprost - Latanoprost - Travoprost I: Beraprost - Iloprost - Treprostinil |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
