Multiple endocrine neoplasia type 2 history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
===Constitutional Symptoms=== | ===Constitutional Symptoms=== | ||
* Tall, thin, "[[Marfan syndrome|marfanoid]]" body build, in which long [[bone]]s are disproportionately elongated | * Tall, thin, "[[Marfan syndrome|marfanoid]]" body build, in which long [[bone]]s are disproportionately elongated. | ||
* Masses beneath [[mucosal]] surfaces in the [[mouth]], [[lip]]s, and [[eye]]s. Numerous yellowish-white, sessile, painless nodules on the [[lip]]s or [[tongue]], with deeper lesions having normal coloration. There may be enough [[neuroma]]s in the body of the [[lip]]s to produce enlargement and a "blubbery lip" appearance. Similar nodules may be seen on the [[sclera]] and [[eyelid]]s | * Masses beneath [[mucosal]] surfaces in the [[mouth]], [[lip]]s, and [[eye]]s. Numerous yellowish-white, sessile, painless [[Nodule (medicine)|nodules]] on the [[lip]]s or [[tongue]], with deeper lesions having normal coloration. There may be enough [[neuroma]]s in the [[body]] of the [[lip]]s to produce enlargement and a "blubbery [[lip]]" appearance. Similar [[Nodule (medicine)|nodules]] may be seen on the [[sclera]] and [[eyelid]]s | ||
* Low [[muscle]] mass, sometimes with [[myopathy]] | * Low [[muscle]] [[mass]], sometimes with [[myopathy]] | ||
* [[Weight loss]] | * [[Weight loss]] | ||
* [[Delayed puberty]] | * [[Delayed puberty]] | ||
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[[Category:Oncology]] | [[Category:Oncology]] | ||
[[CAtegory:Diseases]] | [[CAtegory:Diseases]] | ||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Up-To-Date]] | [[Category:Up-To-Date]] | ||
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{{WS}} | {{WS}} | ||
{{WH}} | {{WH}} | ||
Revision as of 14:24, 14 June 2019
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Multiple endocrine neoplasia type 2 Microchapters |
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Differentiating Multiple endocrine neoplasia type 2 from other Diseases |
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Diagnosis |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Symptoms of multiple endocrine neoplasia type 2 include headache, hoarseness of voice, palpitations, anxiety, and weight loss.
History and Symptoms
Constitutional Symptoms
- Tall, thin, "marfanoid" body build, in which long bones are disproportionately elongated.
- Masses beneath mucosal surfaces in the mouth, lips, and eyes. Numerous yellowish-white, sessile, painless nodules on the lips or tongue, with deeper lesions having normal coloration. There may be enough neuromas in the body of the lips to produce enlargement and a "blubbery lip" appearance. Similar nodules may be seen on the sclera and eyelids
- Low muscle mass, sometimes with myopathy
- Weight loss
- Delayed puberty
- Sweating
- Hand tremor
- Sleeping difficulty
- Lethargy
Gastrointestinal Symptoms
Respiratory Symptoms
Cardiovascular Symptoms
- Chest pain
- Palpitations
- Anxiety often resembling that of a panic attack
- Diaphoresis
Neurologic Symptoms
Ophthalmology Symptoms
- Dry eyes or lack of tears, which is an especially helpful sign in children