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{{Infobox_gene}}
{{GNF_Protein_box
'''Interferon alpha-7''' is a [[protein]] that in humans is encoded by the ''IFNA7'' [[gene]].<ref name="pmid1385305">{{cite journal |vauthors=Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO | title = Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia | journal = Genomics | volume = 14 | issue = 2 | pages = 437–43 |date=Dec 1992 | pmid = 1385305 | pmc =  | doi =10.1016/S0888-7543(05)80238-1 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IFNA7 interferon, alpha 7| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3444| accessdate = }}</ref>
| image = 
| image_source = 
| PDB =
| Name = Interferon, alpha 7
| HGNCid = 5428
| Symbol = IFNA7
| AltSymbols =; IFNA-J
| OMIM = 147567
| ECnumber = 
| Homologene = 88880
| MGIid = 
| Function = {{GNF_GO|id=GO:0005132 |text = interferon-alpha/beta receptor binding}}
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}}
| Process = {{GNF_GO|id=GO:0006952 |text = defense response}} {{GNF_GO|id=GO:0007267 |text = cell-cell signaling}} {{GNF_GO|id=GO:0009615 |text = response to virus}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3444
    | Hs_Ensembl =   
    | Hs_RefseqProtein = NP_066401
    | Hs_RefseqmRNA = NM_021057
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 
    | Hs_GenLoc_start = 
    | Hs_GenLoc_end = 
    | Hs_Uniprot = 
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Interferon, alpha 7''', also known as '''IFNA7''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: IFNA7 interferon, alpha 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3444| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Conti L, Fantuzzi L, Del Cornò M, ''et al.'' |title=Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis. |journal=Immunobiology |volume=209 |issue= 1-2 |pages= 99-115 |year= 2005 |pmid= 15481145 |doi=  }}
*{{cite journal   |vauthors=Conti L, Fantuzzi L, Del Cornò M, etal |title=Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis. |journal=Immunobiology |volume=209 |issue= 1–2 |pages= 99–115 |year= 2005 |pmid= 15481145 |doi=10.1016/j.imbio.2004.02.008 }}
*{{cite journal | author=Capobianchi MR, Ankel H, Ameglio F, ''et al.'' |title=Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer. |journal=AIDS Res. Hum. Retroviruses |volume=8 |issue= 5 |pages= 575-9 |year= 1992 |pmid= 1381203 |doi= }}
*{{cite journal   |vauthors=Capobianchi MR, Ankel H, Ameglio F, etal |title=Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer |journal=AIDS Res. Hum. Retroviruses |volume=8 |issue= 5 |pages= 575–9 |year= 1992 |pmid= 1381203 |doi=10.1089/aid.1992.8.575  }}
*{{cite journal | author=Olopade OI, Bohlander SK, Pomykala H, ''et al.'' |title=Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. |journal=Genomics |volume=14 |issue= 2 |pages= 437-43 |year= 1992 |pmid= 1385305 |doi= }}
*{{cite journal   |vauthors=Tyring SK, Cauda R, Tumbarello M, etal |title=Synthetic peptides corresponding to sequences in HIV envelope gp41 and gp120 enhance in vitro production of interleukin-1 and tumor necrosis factor but depress production of interferon-alpha, interferon-gamma and interleukin-2 |journal=Viral Immunol. |volume=4 |issue= 1 |pages= 33–42 |year= 1991 |pmid= 1905933 |doi=10.1089/vim.1991.4.33  }}
*{{cite journal  | author=Tyring SK, Cauda R, Tumbarello M, ''et al.'' |title=Synthetic peptides corresponding to sequences in HIV envelope gp41 and gp120 enhance in vitro production of interleukin-1 and tumor necrosis factor but depress production of interferon-alpha, interferon-gamma and interleukin-2. |journal=Viral Immunol. |volume=4 |issue= 1 |pages= 33-42 |year= 1991 |pmid= 1905933 |doi=  }}
*{{cite journal  |vauthors=Stine KC, Bolognesi D, Weinhold KJ |title=Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity |journal=Journal of biological response modifiers |volume=8 |issue= 5 |pages= 501–10 |year= 1989 |pmid= 2552026 |doi=  }}
*{{cite journal | author=Stine KC, Bolognesi D, Weinhold KJ |title=Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity. |journal=Journal of biological response modifiers |volume=8 |issue= 5 |pages= 501-10 |year= 1989 |pmid= 2552026 |doi=  }}
*{{cite journal   |vauthors=Cohen S, Velan B, Grosfeld H, etal |title=Cloning, expression and biological activity of a new variant of human interferon alpha identified in virus induced lymphoblastoid cells |journal=Dev. Biol. Stand. |volume=60 |issue= |pages= 111–22 |year= 1985 |pmid= 2995168 |doi=  }}
*{{cite journal | author=Cohen S, Velan B, Grosfeld H, ''et al.'' |title=Cloning, expression and biological activity of a new variant of human interferon alpha identified in virus induced lymphoblastoid cells. |journal=Dev. Biol. Stand. |volume=60 |issue= |pages= 111-22 |year= 1985 |pmid= 2995168 |doi=  }}
*{{cite journal   |vauthors=Henco K, Brosius J, Fujisawa A, etal |title=Structural relationship of human interferon alpha genes and pseudogenes |journal=J. Mol. Biol. |volume=185 |issue= 2 |pages= 227–60 |year= 1985 |pmid= 4057246 |doi=10.1016/0022-2836(85)90401-2 }}
*{{cite journal  | author=Henco K, Brosius J, Fujisawa A, ''et al.'' |title=Structural relationship of human interferon alpha genes and pseudogenes. |journal=J. Mol. Biol. |volume=185 |issue= 2 |pages= 227-60 |year= 1985 |pmid= 4057246 |doi=  }}
*{{cite journal  |vauthors=Ullrich A, Gray A, Goeddel DV, Dull TJ |title=Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster |journal=J. Mol. Biol. |volume=156 |issue= 3 |pages= 467–86 |year= 1982 |pmid= 6181262 |doi=10.1016/0022-2836(82)90261-3 }}
*{{cite journal | author=Ullrich A, Gray A, Goeddel DV, Dull TJ |title=Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster. |journal=J. Mol. Biol. |volume=156 |issue= 3 |pages= 467-86 |year= 1982 |pmid= 6181262 |doi=  }}
*{{cite journal   |vauthors=Ameglio F, Capobianchi MR, Castilletti C, etal |title=Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with the induction of other cytokines |journal=Clin. Exp. Immunol. |volume=95 |issue= 3 |pages= 455–8 |year= 1994 |pmid= 7511078 |doi= 10.1111/j.1365-2249.1994.tb07018.x| pmc=1535081 }}
*{{cite journal  | author=Ameglio F, Capobianchi MR, Castilletti C, ''et al.'' |title=Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with the induction of other cytokines. |journal=Clin. Exp. Immunol. |volume=95 |issue= 3 |pages= 455-8 |year= 1994 |pmid= 7511078 |doi= }}
*{{cite journal  |vauthors=Ankel H, Capobianchi MR, Castilletti C, Dianzani F |title=Interferon induction by HIV glycoprotein 120: role of the V3 loop |journal=Virology |volume=205 |issue= 1 |pages= 34–43 |year= 1994 |pmid= 7526537 |doi= 10.1006/viro.1994.1617 }}
*{{cite journal | author=Ankel H, Capobianchi MR, Castilletti C, Dianzani F |title=Interferon induction by HIV glycoprotein 120: role of the V3 loop. |journal=Virology |volume=205 |issue= 1 |pages= 34-43 |year= 1994 |pmid= 7526537 |doi= 10.1006/viro.1994.1617 }}
*{{cite journal   |vauthors=Nair MP, Chadha KC, Stadler I, etal |title=Differential effects of human immunodeficiency virus type 1 envelope protein gp120 on interferon production by mononuclear cells from adults and neonates |journal=Clin. Diagn. Lab. Immunol. |volume=2 |issue= 4 |pages= 434–8 |year= 1995 |pmid= 7583919 |doi= | pmc=170174  }}
*{{cite journal | author=Nair MP, Chadha KC, Stadler I, ''et al.'' |title=Differential effects of human immunodeficiency virus type 1 envelope protein gp120 on interferon production by mononuclear cells from adults and neonates. |journal=Clin. Diagn. Lab. Immunol. |volume=2 |issue= 4 |pages= 434-8 |year= 1995 |pmid= 7583919 |doi=  }}
*{{cite journal   |vauthors=Borghi P, Fantuzzi L, Varano B, etal |title=Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages |journal=J. Virol. |volume=69 |issue= 2 |pages= 1284–7 |year= 1995 |pmid= 7815507 |doi= | pmc=188705 }}
*{{cite journal | author=Borghi P, Fantuzzi L, Varano B, ''et al.'' |title=Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages. |journal=J. Virol. |volume=69 |issue= 2 |pages= 1284-7 |year= 1995 |pmid= 7815507 |doi= }}
*{{cite journal   |vauthors=Capobianchi MR, Ameglio F, Cordiali Fei P, etal |title=Coordinate induction of interferon alpha and gamma by recombinant HIV-1 glycoprotein 120 |journal=AIDS Res. Hum. Retroviruses |volume=9 |issue= 10 |pages= 957–62 |year= 1994 |pmid= 7904170 |doi=10.1089/aid.1993.9.957  }}
*{{cite journal | author=Capobianchi MR, Ameglio F, Cordiali Fei P, ''et al.'' |title=Coordinate induction of interferon alpha and gamma by recombinant HIV-1 glycoprotein 120. |journal=AIDS Res. Hum. Retroviruses |volume=9 |issue= 10 |pages= 957-62 |year= 1994 |pmid= 7904170 |doi=  }}
*{{cite journal   |vauthors=Chen YH, Böck G, Vornhagen R, etal |title=HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells |journal=Int. Arch. Allergy Immunol. |volume=104 |issue= 3 |pages= 227–31 |year= 1994 |pmid= 7913356 |doi=10.1159/000236670 }}
*{{cite journal  | author=Chen YH, Böck G, Vornhagen R, ''et al.'' |title=HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells. |journal=Int. Arch. Allergy Immunol. |volume=104 |issue= 3 |pages= 227-31 |year= 1994 |pmid= 7913356 |doi=  }}
*{{cite journal  |vauthors=Francis ML, Meltzer MS |title=Induction of IFN-alpha by HIV-1 in monocyte-enriched PBMC requires gp120-CD4 interaction but not virus replication |journal=J. Immunol. |volume=151 |issue= 4 |pages= 2208–16 |year= 1993 |pmid= 8345204 |doi=  }}
*{{cite journal  | author=Francis ML, Meltzer MS |title=Induction of IFN-alpha by HIV-1 in monocyte-enriched PBMC requires gp120-CD4 interaction but not virus replication. |journal=J. Immunol. |volume=151 |issue= 4 |pages= 2208-16 |year= 1993 |pmid= 8345204 |doi= }}
*{{cite journal  |vauthors=Shirazi Y, Pitha PM |title=Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells |journal=Virology |volume=193 |issue= 1 |pages= 303–12 |year= 1993 |pmid= 8438572 |doi= 10.1006/viro.1993.1126 }}
*{{cite journal | author=Shirazi Y, Pitha PM |title=Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells. |journal=Virology |volume=193 |issue= 1 |pages= 303-12 |year= 1993 |pmid= 8438572 |doi= 10.1006/viro.1993.1126 }}
*{{cite journal   |vauthors=Ankel H, Capobianchi MR, Frezza F, etal |title=Interferon induction by HIV-1-infected cells: a possible role of sulfatides or related glycolipids |journal=Virology |volume=221 |issue= 1 |pages= 113–9 |year= 1996 |pmid= 8661419 |doi= 10.1006/viro.1996.0357 }}
*{{cite journal | author=Ankel H, Capobianchi MR, Frezza F, ''et al.'' |title=Interferon induction by HIV-1-infected cells: a possible role of sulfatides or related glycolipids. |journal=Virology |volume=221 |issue= 1 |pages= 113-9 |year= 1996 |pmid= 8661419 |doi= 10.1006/viro.1996.0357 }}
*{{cite journal   |vauthors=Tiefenbrun N, Melamed D, Levy N, etal |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934–44 |year= 1996 |pmid= 8668211 |doi= | pmc=231390  }}
*{{cite journal  | author=Tiefenbrun N, Melamed D, Levy N, ''et al.'' |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934-44 |year= 1996 |pmid= 8668211 |doi=  }}
*{{cite journal  |vauthors=Schols D, De Clercq E |title=Human immunodeficiency virus type 1 gp120 induces anergy in human peripheral blood lymphocytes by inducing interleukin-10 production |journal=J. Virol. |volume=70 |issue= 8 |pages= 4953–60 |year= 1996 |pmid= 8764000 |doi= | pmc=190447 }}
*{{cite journal  | author=Schols D, De Clercq E |title=Human immunodeficiency virus type 1 gp120 induces anergy in human peripheral blood lymphocytes by inducing interleukin-10 production. |journal=J. Virol. |volume=70 |issue= 8 |pages= 4953-60 |year= 1996 |pmid= 8764000 |doi= }}
*{{cite journal  |vauthors=Hussain M, Gill DS, Liao MJ |title=Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population |journal=J. Interferon Cytokine Res. |volume=16 |issue= 10 |pages= 853–9 |year= 1997 |pmid= 8910771 |doi=10.1089/jir.1996.16.853  }}
*{{cite journal  | author=Hussain M, Gill DS, Liao MJ |title=Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population. |journal=J. Interferon Cytokine Res. |volume=16 |issue= 10 |pages= 853-9 |year= 1997 |pmid= 8910771 |doi= }}
}}
}}
{{refend}}
{{refend}}
{{Cytokine receptor modulators}}
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{{protein-stub}}
{{protein-stub}}

Latest revision as of 07:38, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Interferon alpha-7 is a protein that in humans is encoded by the IFNA7 gene.[1][2]


References

  1. Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (Dec 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.
  2. "Entrez Gene: IFNA7 interferon, alpha 7".

Further reading