Chronic renal failure causes: Difference between revisions

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Common causes of chronic renal failure include [[diabetic nephropathy]], [[hypertension]], and [[glomerulonephritis]]. The commonest cause of stage 5 CKD in the  U.S. is diabetes and is characterized by [[proteinuria]] and bilaterally enlarged kidneys. [[Hypertension]] is the second most common cause of Stage 5 CKD in the  US, and often co-exists in diabetic patients.
Common causes of chronic renal failure include [[diabetic nephropathy]], [[hypertension]], and [[glomerulonephritis]]. The commonest cause of stage 5 CKD in the  U.S. is diabetes and is characterized by [[proteinuria]] and bilaterally enlarged kidneys. [[Hypertension]] is the second most common cause of Stage 5 CKD in the  US, and often co-exists in diabetic patients.


==Complete list of Causes by Organ System==
===Causes of CKD===  
{|style="width:80%; height:100px" border="1"
Several conditions, exposures, and drugs can lead to renal injury with progression to CKD. The following list is a summary of most etiologies of CKD:
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |[[Malignant hypertension]], [[Systemic hypertension]]
|-
|-bgcolor="LightSteelBlue"
| '''Chemical / poisoning'''
|bgcolor="Beige"| [[Arsenic]], [[Bismuth]], [[Mercury]], [[Lead]], [[Nitrosourea compounds]], [[Pentamidine]], [[Radiocontrast agents]]
|-
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
|bgcolor="Beige"|[[Acetominophen]], [[Acyclovir ]], [[Allopurinol]], [[Aminoglycosides]], [[Angiotensin-converting enzyme inhibitors]], [[Anticoagulants]], [[Aspirin]], [[bevacizumab]], [[Bismuth]], [[Cisplatin]], [[Carboplatin]], [[Carbon tetrachloride]], [[Carmustine]], [[Celecoxib]], [[Chloroquine]], [[Cimetidine]], [[Cocaine]], [[Cyclosporine]], [[Erythromycin]],[[Esomeprazole ]], [[Foscarnet]], [[Fenofibrate]], [[Furosemide]], [[Gentamicin]], [[Gemfibrozil]], [[Hydroxychloroquine]],[[Ibuprofen]], [[Indinavir]], [[Infliximab ]], [[Ifosfamide]], [[Isoniazid]], [[Lansoprazole ]], [[Laxatives]], [[Lithium]],[[Lomustine]], [[Methicillin]], [[Mitomycin C]], [[Mesalamine]], [[Naproxen]], [[Interferons]], [[Omeprazole ]], [[Pamidronate]],[[Pantoprazole ]], [[Penicillin]], [[Phenytoin ]], [[Propylthiouracil]], [[Quinine]], [[Rabeprazole]], [[Rifampicin]], [[Sulfa-containing antibiotics]], [[Sulfonamides]], [[Tacrolimus]], [[Tenofovir]], [[Thiazides]],[[Trimethadione ]], [[Vancomycin]]
|-
|-bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"| [[Alport's syndrome]], [[Balkan endemic nephropathy]], [[Adenine phosphoribosyltransferase deficiency]], [[Alström syndrome]], [[Barakat syndrome]], [[Bardet-Biedl syndrome]], [[Fabry's Disease]], [[Alport's syndrome|Hereditary Nephritis]], [[Jeune's disease]], [[Lecithin cholesterol acyltransferase deficiency]], [[Lesch-Nyhan syndrome]], [[Loken Senior syndrome]], [[Lowe syndrome]], [[Nail-Patella Syndrome]],[[Papillorenal syndrome]], [[Polycystic kidney disease]], [[Sickle cell disease]], [[Townes-Brocks syndrome]], [[X-linked recessive nephrolithiasis type 1]],[[Vesicoureteral reflux]], [[X-linked hypophosphatemia]]
|-
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"|[[Acute intermittent porphyria]], [[Light chain disease]], [[Myeloma]], [[Normocytic normochromic anemia]], [[Renal vein thrombosis]], [[Thrombotic thrombocytopenic purpura]]
|-
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"|[[Chronic pyelonephritis]], [[Schistosoma haematobium]], [[Tuberculosis]], [[Hantavirus]]
|-
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal / Ortho'''
|bgcolor="Beige"|[[Idiopathic multicentric osteolysis]]
|-
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Nutritional / Metabolic'''
|bgcolor="Beige"|[[Calcium phosphate|Calcium phosphate deposition]], [[cystinosis]], [[Diabetic nephropathy]], [[Fabry's disease]], [[Hyperkalemia]],[[Hyperlipidemia]], [[Hyperoxaluria]], [[Hyperphosphatemia]], [[Metabolic acidosis]], [[Oxalosis]], [[X-linked hypophosphatemia]]
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"| [[Metastatic prostate cancer]]
|-
|-bgcolor="LightSteelBlue"
| '''Opthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose / Toxicity'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"|[[Goodpasture’s syndrome]]
|-
|-bgcolor="LightSteelBlue"
| '''Renal / Electrolyte'''
|bgcolor="Beige"| [[Analgesic nephropathy]], [[Alport's syndrome]], [[Balkan endemic nephropathy]], [[Chronic Glomerulonephritis]],[[Chronic Pyelonephritis]], [[Congenital Nephrotic Syndrome]], [[Diabetic nephropathy]], [[Goodpasture’s syndrome]], [[Focal glomerulosclerosis]], [[Glomerulosclerosis]], [[Hypertensive nephrosclerosis ]], [[Alport's syndrome|Hereditary Nephritis]], [[IgA nephropathy]],[[Interstitial Nephritis]],  [[Lupus nephritis]], [[Papillorenal syndrome]], [[Polycystic kidney disease]],[[Medullary cystic kidney disease]], [[Medullary sponge kidney]], [[Membranoproliferative Glomerulonephritis]], [[Membranous nephritis]], [[Nephrolithiasis]],[[Nephrosclerosis]], [[Obstructive uropathy]], [[Proteinuria]], [[Reflux nephropathy]], [[Renal artery stenosis]], [[Renal tubular acidosis|Type IV renal tubular acidosis]], [[Vesicoureteral reflux]], [[Pyelonephritis|Xanthogranulomatous pyelonephritis]]
|-
|-bgcolor="LightSteelBlue"
| '''Rheum / Immune / Allergy'''
|bgcolor="Beige"|[[Goodpasture’s syndrome]], [[Lupus nephritis]], [[Rheumatoid arthritis]], [[Scleroderma]], [[Systemic Lupus Erythematosus]], [[Systemic sclerosis]], [[Vasculitis]], [[Wegener's granulomatosis]]
|-
|-bgcolor="LightSteelBlue"
| '''Sexual'''
|bgcolor="Beige"| [[Benign prostatic hyperplasia]], [[Denys-Drash syndrome]], [[Metastatic prostate cancer ]]
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| [[Obstructive uropathy]], [[Reflux nephropathy]], [[Hydronephrosis]]
|-
|-bgcolor="LightSteelBlue"
| '''Dental'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"|[[Amyloidosis]], [[Chronic inflammation]], [[Hemolytic uremic syndrome]]
|-
|}


===Causes in Alphabetical Order===  
====Conditions:====
{{MultiCol}}
{{MultiCol}}
*[[Acetominophen]]
 
*[[Acute intermittent porphyria]]
*[[Acute intermittent porphyria]]
*[[Acyclovir ]]
 
*[[Adenine phosphoribosyltransferase deficiency]]
*[[Adenine phosphoribosyltransferase deficiency]]
*[[Allopurinol]]
 
*[[Alport's syndrome]]
*[[Alport's syndrome]]
*[[Alström syndrome]]
*[[Alström syndrome]]
*[[Aminoglycosides]]
 
*[[Amyloidosis]]
*[[Amyloidosis]]
*[[Analgesic nephropathy]]
 
*[[Angiotensin-converting enzyme inhibitors]]
 
*[[Anticoagulants]]
*[[Anticoagulants]]
*[[Aspirin]]
 
*[[Balkan endemic nephropathy]]
*[[Balkan endemic nephropathy]]
*[[Barakat syndrome]]
*[[Barakat syndrome]]
*[[Bardet-Biedl syndrome]]
*[[Bardet-Biedl syndrome]]
*[[Benign prostatic hyperplasia]]
*[[Benign prostatic hyperplasia]]
*[[Bevacizumab]]
 
*[[Bismuth]]
 
*[[Calcium phosphate|Calcium phosphate deposition]]
*[[Carbon tetrachloride ]]
*[[Carbon tetrachloride ]]
*[[Carboplatin]]
 
*[[Carmustine]]
*[[Celecoxib]]
*[[Chloroquine]]
*[[Chronic Glomerulonephritis]]
*[[Chronic Glomerulonephritis]]
*[[Chronic inflammation]]
*[[Chronic inflammation]]
*[[Chronic Pyelonephritis]]
*[[Chronic Pyelonephritis]]
*[[Cimetidine]]
 
*[[Cisplatin]]
*[[Cocaine]]
*[[Cocaine]]
*[[Congenital Nephrotic Syndrome]]
*[[Congenital Nephrotic Syndrome]]
*[[Cyclosporine]]
 
*[[Cystinosis]]
*[[Cystinosis]]
*[[Denys-Drash syndrome]]
*[[Denys-Drash syndrome]]
*[[Diabetic nephropathy]]
*[[Diabetic nephropathy]]
*[[Erythromycin]]
 
*[[Esomeprazole ]]
*[[Fabry's Disease]]
*[[Fabry's Disease]]
*[[Fenofibrate]]
 
*[[Furosemide]]
 
*[[Focal glomerulosclerosis]]
*[[Focal glomerulosclerosis]]
*[[Foscarnet]]
*[[Foscarnet]]
*[[Gemfibrozil]]
*[[Gemfibrozil]]
*[[Gentamicin]]
 
*[[Glomerulosclerosis]]
*[[Glomerulosclerosis]]
*[[Goodpasture’s syndrome]]
*[[Goodpasture’s syndrome]]
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*[[Hemolytic uremic syndrome]]
*[[Hemolytic uremic syndrome]]
*[[Alport's syndrome|Hereditary Nephritis]]
*[[Alport's syndrome|Hereditary Nephritis]]
*[[Hydroxychloroquine]]
 
*[[Hyperkalemia]]
 
*[[Hyperlipidemia]]
 
*[[Hyperoxaluria]]
*[[Hyperoxaluria]]
*[[Hyperphosphatemia]]
 
*[[Hypertensive nephrosclerosis ]]
*[[Hypertensive nephrosclerosis ]]
*[[Ibuprofen]]
 
*[[Idiopathic multicentric osteolysis]]
*[[Idiopathic multicentric osteolysis]]
*[[IgA nephropathy]]
*[[IgA nephropathy]]
*[[Indinavir]]
 
*[[Infliximab ]]
*[[Interstitial Nephritis]]
*[[Interstitial Nephritis]]
*[[Ifosfamide]]
*[[Ifosfamide]]
*[[Isoniazid]]
*[[Isoniazid]]
*[[Jeune's disease|Jeune's thoracic dystrophy syndrome]]
*[[Jeune's disease|Jeune's thoracic dystrophy syndrome]]
*[[Lansoprazole ]]
 
*[[Laxatives]]
 
*[[Lead]]
*[[Lead]]
*[[Lecithin cholesterol acyltransferase deficiency]]
*[[Lecithin cholesterol acyltransferase deficiency]]
*[[Lesch-Nyhan syndrome]]
*[[Lesch-Nyhan syndrome]]
*[[Light chain disease]]
*[[Light chain disease]]
*[[Lithium]]
 
{{ColBreak}}
{{ColBreak}}
*[[Loken Senior syndrome]]
*[[Loken Senior syndrome]]
*[[Lomustine]]
 
*[[Lowe syndrome]]
*[[Lowe syndrome]]
*[[Lupus nephritis]]
*[[Lupus nephritis]]
Line 207: Line 88:
*[[Metabolic acidosis]]
*[[Metabolic acidosis]]
*[[Metastatic prostate cancer ]]
*[[Metastatic prostate cancer ]]
*[[Methicillin]]
 
*[[Mesalamine]]
*[[Mitomycin C]]
*[[Myeloma]]
*[[Myeloma]]
*[[Nail-Patella Syndrome]]
*[[Nail-Patella Syndrome]]
*[[Naproxen]]
 
*[[Nephrolithiasis]]
*[[Nephrolithiasis]]
*[[Nephrosclerosis]]
*[[Nephrosclerosis]]
*[[Nitrosourea compounds]]
 
*[[Normocytic normochromic anemia]]
*[[Normocytic normochromic anemia]]
*[[Interferons]]
 
*[[Obstructive uropathy]]
*[[Obstructive uropathy]]
*[[Omeprazole ]]
 
*[[Oxalosis]]
*[[Oxalosis]]
*[[Pamidronate]]
 
*[[Pantoprazole ]]
 
*[[Papillorenal syndrome]]
*[[Papillorenal syndrome]]
*[[Penicillin]]
 
*[[Pentamidine]]
*[[Phenytoin ]]
*[[Polycystic kidney disease]]
*[[Polycystic kidney disease]]
*[[Propylthiouracil]]
 
*[[Proteinuria]]
*[[Proteinuria]]
*[[Quinine]]
 
*[[Rabeprazole]]
 
*[[Radiocontrast agents]]
*[[Radiocontrast agents]]
*[[Reflux nephropathy]]
*[[Reflux nephropathy]]
Line 237: Line 114:
*[[Renal vein thrombosis]]
*[[Renal vein thrombosis]]
*[[Rheumatoid arthritis]]
*[[Rheumatoid arthritis]]
*[[Rifampicin]]
 
*[[Schistosoma haematobium]]
*[[Schistosoma haematobium]]
*[[Scleroderma]]
*[[Scleroderma]]
*[[Sickle cell disease ]]
*[[Sickle cell disease ]]
*[[Sulfa-containing antibiotics]]
 
*[[Sulfonamides]]
*[[Systemic hypertension]]
*[[Systemic hypertension]]
*[[Systemic Lupus Erythematosus]]
*[[Systemic Lupus Erythematosus]]
*[[Systemic sclerosis]]
*[[Systemic sclerosis]]
*[[Tacrolimus]]
 
*[[Tenofovir]]
*[[Thrombotic thrombocytopenic purpura]]
*[[Thrombotic thrombocytopenic purpura]]
*[[Thiazides]]
 
*[[Townes-Brocks syndrome]]
*[[Townes-Brocks syndrome]]
*[[Trimethadione ]]
 
*[[Tuberculosis]]
*[[Tuberculosis]]
*[[Renal tubular acidosis|Type IV renal tubular acidosis]]
*[[Renal tubular acidosis|Type IV renal tubular acidosis]]
*[[Vancomycin]]
 
*[[Vasculitis]]
*[[Vasculitis]]
*[[Vesicoureteral reflux]]
*[[Vesicoureteral reflux]]
Line 262: Line 137:
*[[X-linked recessive nephrolithiasis type 1]]
*[[X-linked recessive nephrolithiasis type 1]]
{{EndMultiCol}}
{{EndMultiCol}}
====Drugs====
*[[Acetominophen]]
*[[Acyclovir ]]
*[[Allopurinol]]
*[[Aminoglycosides]]
*[[Angiotensin-converting enzyme inhibitors]]
*[[Aspirin]]
*[[Bevacizumab]]
*[[Bismuth]]
*[[Carboplatin]]
*[[Carmustine]]
*[[Chloroquine]]
*[[Cisplatin]]
*[[Cyclosporine]]
*[[Erythromycin]]
*[[Furosemide]]
*[[Gentamicin]]
*[[Hydroxychloroquine]]
*[[NSAIDs]]
*[[Protease Inhibitors]]
*[[Infliximab ]]
*[[Laxatives]]
*[[Lithium]]
*[[Lomustine]]
*[[Methicillin]]
*[[Mesalamine]]
*[[Mitomycin C]]
*[[Interferons]]
*[[Nitrosoureas]]
*[[Pamidronate]]
*[[Penicillin]]
*[[Pentamidine]]
*[[Phenytoin ]]
*[[Propylthiouracil]]
*[[Quinine]]
*[[Rifampicin]]
*[[Sulfa-containing antibiotics]]
*[[Sulfonamides]]
*[[Tacrolimus]]
*[[Thiazides]]
*[[Vancomycin]]


==References==
==References==

Revision as of 00:00, 27 October 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]

Overview

Common causes of chronic renal failure include diabetic nephropathy, hypertension, and glomerulonephritis. The commonest cause of stage 5 CKD in the U.S. is diabetes and is characterized by proteinuria and bilaterally enlarged kidneys. Hypertension is the second most common cause of Stage 5 CKD in the US, and often co-exists in diabetic patients.

Causes of CKD

Several conditions, exposures, and drugs can lead to renal injury with progression to CKD. The following list is a summary of most etiologies of CKD:

Conditions:









Drugs

References



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