Appendix cancer other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
[[Positron emission tomography]] (PET) and [[scintigraphy]] are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer. | [[Positron emission tomography]] (PET) and [[scintigraphy]] are among other [[Imaging|imaging modalities]] that may be helpful in the [[diagnosis]] and management of [[Vermiform appendix|appendix]] [[Cancer|cancer.]] | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
* The followings are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer: | * The followings are among other [[Imaging studies|imaging modalities]] that may be helpful in the [[diagnosis]] and management of appendix cancer: | ||
:* [[Somatostatin]] [[scintigraphy]] with 111-indium-octreotide | :* [[Somatostatin]] [[scintigraphy]] with 111-indium-[[octreotide]]<ref name="pmid9145069">Kisker O, Bartsch D, Weinel RJ, Joseph K, Welcke UH, Zaraca F et al. (1997) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=9145069 The value of somatostatin-receptor scintigraphy in newly diagnosed endocrine gastroenteropancreatic tumors.] ''J Am Coll Surg'' 184 (5):487-92. PMID: [https://pubmed.gov/9145069 9145069]</ref> | ||
::* High sensitivity and specificity for | ::* High [[Sensitivity (tests)|sensitivity]] and [[Specificity (tests)|specificity]] for both functioning and non-functioning [[Carcinoid Tumor|carcinoid]] tumors | ||
::* Most sensitive imaging method to evaluate extrahepatic metastases | ::* Most [[Sensitivity (tests)|sensitive]] [[Imaging|imaging method to evaluate]] [[Metastases|extrahepatic metastases]] | ||
::* Useful in treatment planning | ::* Useful in treatment planning | ||
::* Indicates response to octreotide analogues | ::* Indicates response to [[Octreotide|octreotide analogues]] | ||
:* [[Bone]] [[scintigraphy]] with 99mTc-methylene diphosphonate (99mTcMDP) | :* [[Bone]] [[scintigraphy]] with 99mTc-methylene diphosphonate (99mTcMDP)<ref name="pmid11158063" /> | ||
:* MIBG scintigraphy <ref name="pmid11158063">Kaltsas G, Korbonits M, Heintz E, Mukherjee JJ, Jenkins PJ, Chew SL et al. (2001) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=11158063 Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors.] ''J Clin Endocrinol Metab'' 86 (2):895-902. [http://dx.doi.org/10.1210/jcem.86.2.7194 DOI:10.1210/jcem.86.2.7194] PMID: [https://pubmed.gov/11158063 11158063]</ref> | :* MIBG [[Nuclear medicine|scintigraphy]] <ref name="pmid11158063">Kaltsas G, Korbonits M, Heintz E, Mukherjee JJ, Jenkins PJ, Chew SL et al. (2001) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=11158063 Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors.] ''J Clin Endocrinol Metab'' 86 (2):895-902. [http://dx.doi.org/10.1210/jcem.86.2.7194 DOI:10.1210/jcem.86.2.7194] PMID: [https://pubmed.gov/11158063 11158063]</ref> | ||
::* | ::*Distinguish between primary and [[Cancer of unknown primary origin|metastatic tumors]] | ||
::*Detecting carcinoid tumors that are negative on OctreoScan | ::*Detecting [[Carcinoid Tumor|carcinoid tumors]] that are negative on OctreoScan | ||
:* [[Positron emission tomography]] (PET) : Figure below demonstrates | :* [[Positron emission tomography]] (PET): | ||
:** [[Positron emission tomography|PET]]-[[Computed tomography|CT]] scan will show high uptake in the metastasis points as well residual tumor and/or [[peritoneal carcinomatosis]]. | |||
:** Figure below demonstrates post-operative [[Positron emission tomography|PET-CT]] [[Computed tomography|scan]] of a [[Carcinoid|patient with carcinoid tumor]].<ref name="pmid15153441">Sundin A, Eriksson B, Bergström M, Långström B, Oberg K, Orlefors H (2004) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=15153441 PET in the diagnosis of neuroendocrine tumors.] ''Ann N Y Acad Sci'' 1014 ():246-57. PMID: [https://pubmed.gov/15153441 15153441]</ref> | |||
[[Image:Appendiceal-adenocarcinoma-complicated-by-retroperitoneal-abscess (4).jpg|thumb|center|500px|'''Appendiceal adenocarcinoma complicated by retroperitoneal abscess.''' ''Post-operative PET-CT scan shows high uptake posterior to the cecum, suspicious for residual tumor and/or peritoneal carcinomatosis.'' Case courtesy of Dr Francis Fortin, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/58007">rID: 58007</a>]] | [[Image:Appendiceal-adenocarcinoma-complicated-by-retroperitoneal-abscess (4).jpg|thumb|center|500px|'''Appendiceal adenocarcinoma complicated by retroperitoneal abscess.''' ''Post-operative PET-CT scan shows high uptake posterior to the cecum, suspicious for residual tumor and/or peritoneal carcinomatosis.'' Case courtesy of Dr Francis Fortin, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/58007">rID: 58007</a>]] | ||
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[[Category:Oncology]] | |||
[[Category:Up-To-Date]] | |||
[[Category: Radiology]] | |||
Latest revision as of 17:58, 22 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
Positron emission tomography (PET) and scintigraphy are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer.
Other Imaging Findings
- The followings are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer:
- Somatostatin scintigraphy with 111-indium-octreotide[1]
- High sensitivity and specificity for both functioning and non-functioning carcinoid tumors
- Most sensitive imaging method to evaluate extrahepatic metastases
- Useful in treatment planning
- Indicates response to octreotide analogues
- Bone scintigraphy with 99mTc-methylene diphosphonate (99mTcMDP)[2]
- MIBG scintigraphy [2]
- Distinguish between primary and metastatic tumors
- Detecting carcinoid tumors that are negative on OctreoScan
- Positron emission tomography (PET):
- PET-CT scan will show high uptake in the metastasis points as well residual tumor and/or peritoneal carcinomatosis.
- Figure below demonstrates post-operative PET-CT scan of a patient with carcinoid tumor.[3]
.jpg)
References
- ↑ Kisker O, Bartsch D, Weinel RJ, Joseph K, Welcke UH, Zaraca F et al. (1997) The value of somatostatin-receptor scintigraphy in newly diagnosed endocrine gastroenteropancreatic tumors. J Am Coll Surg 184 (5):487-92. PMID: 9145069
- ↑ 2.0 2.1 Kaltsas G, Korbonits M, Heintz E, Mukherjee JJ, Jenkins PJ, Chew SL et al. (2001) Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors. J Clin Endocrinol Metab 86 (2):895-902. DOI:10.1210/jcem.86.2.7194 PMID: 11158063
- ↑ Sundin A, Eriksson B, Bergström M, Långström B, Oberg K, Orlefors H (2004) PET in the diagnosis of neuroendocrine tumors. Ann N Y Acad Sci 1014 ():246-57. PMID: 15153441