Appendix cancer other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Overview

Positron emission tomography (PET) and scintigraphy are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer.

Other Imaging Findings

• The followings are among other imaging modalities that may be helpful in the diagnosis and management of appendix cancer:

• Somatostatin scintigraphy with 111-indium-octreotide

• High sensitivity and specificity for both functioning and non-functioning carcinoid tumors
• Most sensitive imaging method to evaluate extrahepatic metastases
• Useful in treatment planning
• Indicates response to octreotide analogues

• Bone scintigraphy with 99mTc-methylene diphosphonate (99mTcMDP)
• MIBG scintigraphy

• Distinguish between primary and metastatic tumors
• Detecting carcinoid tumors that are negative on OctreoScan

• Positron emission tomography (PET):
  • PET-CT scan will show high uptake in the metastasis points as well residual tumor and/or peritoneal carcinomatosis.
  • Figure below demonstrates post-operative PET-CT scan of a patient with carcinoid tumor.

Appendiceal adenocarcinoma complicated by retroperitoneal abscess. Post-operative PET-CT scan shows high uptake posterior to the cecum, suspicious for residual tumor and/or peritoneal carcinomatosis. Case courtesy of Dr Francis Fortin, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/58007">rID: 58007</a>