Lupus nephritis causes: Difference between revisions
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'''Editor-In-Chief:''' [[User:C Michael Gibson|C. Michael Gibson, M.S., M.D.]] | '''Editor-In-Chief:''' [[User:C Michael Gibson|C. Michael Gibson, M.S., M.D.]] [Mailto:charlesmichaelgibson@gmail.com| <nowiki>[1]</nowiki>]; '''Associate Editor(s)-in-Chief:''' [[User:Okamal|Omer Kamal, M.D.]] [Mailto:okamal@bidmc.harvard.edu| <nowiki>[2]</nowiki>] | ||
== Overview == | == Overview == | ||
Revision as of 20:25, 19 July 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D. [2]
Overview
There are no established direct causes of systemic lupus erythematosus. Common contributory factors in the development of systemic lupus erythematosus include geneticpredisposition, auto-immune diseases, and use of drugs. Less common factors include environmental factors and exposure to ultraviolet (UV) light.
Causes
- Genetic predisposition:[1]
- HLA class polymorphism
- Complement genes
- Female sexual gene due to high levels of estrogen and prolactin
- Auto-immune disease[2]
- Exposure to ultraviolet (UV) light[3]
- Can exacerbate or induce systemic manifestations of SLE
- Drug-induced lupus
- Acebutolol
- Adalimumab
- Anastrozole
- Bupropion
- Captopril
- Cilazapril
- Cinnarizine/thiethylperazine
- Diltiazem
- Docetaxel
- Doxorubicin
- D-penicillamine
- Etanercept
- Gemcitabine
- Glyburide
- Golimumab
- Griseofulvin
- Hydrochlorothiazide
- Infliximab
- Interferon-alpha
- Interferon-beta
- Oxprenolol
- Phenytoin
- Lamotrigine
- Lansoprazole
- Leflunomide
- Leuprorelin
- Naproxen
- Nifedipine
- Nitrendipine
- Omeprazole
- Paclitaxel
- Pantoprazole
- Piroxicam
- Pravastatin
- Ranitidine
- Simvastatin
- Spironolactone
- Tamoxifen
- Terbinafine
- Ticlopidine
- Verapamil
- Sulfonamides
References
- ↑ Schur PH (December 1995). "Genetics of systemic lupus erythematosus". Lupus. 4 (6): 425–37. doi:10.1177/096120339500400603. PMID 8749564.
- ↑ Cutolo M, Sulli A, Seriolo B, Accardo S, Masi AT (1995). "Estrogens, the immune response and autoimmunity". Clin. Exp. Rheumatol. 13 (2): 217–26. PMID 7656468.
- ↑ Cooper GS, Dooley MA, Treadwell EL, St Clair EW, Gilkeson GS (October 2002). "Risk factors for development of systemic lupus erythematosus: allergies, infections, and family history". J Clin Epidemiol. 55 (10): 982–9. PMID 12464374.