Acoustic neuroma epidemiology and demographics: Difference between revisions

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{{Acoustic neuroma}}
{{Acoustic neuroma}}
{{CMG}}{{AE}}{{Simrat}}
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==Overview==
==Overview==
The incidence of acoustic neuroma is approximately 1 per 100,000 individuals worldwide. The prevalence of acoustic neuroma is approximately 2,500 new cases per 100,000 individuals. Women are more commonly affected with acoustic neuroma than men.Most cases of acoustic neuroma develop in individuals between the ages of 30 and 60.<ref>{{Cite web | title =NIH Acoustic neuroma Incidence| url =http://www.nidcd.nih.gov/health/hearing/pages/acoustic_neuroma.aspx }}</ref>
The [[incidence]] of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals. The [[prevalence]] of acoustic neuroma is approximately 0.2 per 100,000 individuals. Women are more commonly affected by acoustic neuroma than men. Most cases of acoustic neuroma develop in individuals between 30 and 60 years of age.
==Epidemiology and Demographic==
 
Acoustic neuroma account for 7-8% of all primary intracranial tumours 2 and 75-90% of cerebellopontine angle masses 1-2,8. Bilateral vestibular schwannomas are highly suggestive of neurofibromatosis type 2 (NF2), although bilateral tumours are encountered in the familial form of acoustic schwannomas in the absence of other stigmata of NF2.<ref>{{Cite web | title =Radiopedia Acoustic neuroma Epidemiology| url =http://radiopaedia.org/articles/acoustic-schwannoma }}</ref>  
==Epidemiology and Demographics==
Acoustic neuroma accounts for 7 - 8% of all primary [[Cranium|intracranial]] [[tumors]] and 75 - 90% of [[cerebellopontine]] angle masses. [[Bilateral]] vestibular [[schwannomas]] are highly suggestive of [[neurofibromatosis type 2|neurofibromatosis type 2 (NF2)]], although [[bilateral]] [[tumors]] are encountered in the [[familial]] form of acoustic [[Schwannoma|schwannomas]] in the absence of other stigmata of [[Neurofibromatosis type II|NF2]].<ref name="radio">Acoustic Schwannoma. Radiopedia(2015) http://radiopaedia.org/articles/acoustic-schwannoma Accessed on October 2 2015</ref><ref>{{Cite journal|last=Thomas J. Gal, MD, MPH, Jennifer Shinn, PhD, and Bin Huang, PhD, Lexington, KY|first=|date=2010|title=Current epidemiology and management trends in acoustic neuroma|url=|journal=Otolaryngology–Head and Neck Surgery|volume=|pages=|via=}}</ref><ref name="Medline Plus">Acoustic neuroma. Medline Plus(2015) https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm Accessed on October 2 2015</ref>
 
{| style="border: 3px; margin: 1px; font-size: 90%; width: 400px; align=" center "
! colspan="3" style="background: #5579ff; width 400px; " | {{fontcolor|#FFF|Age-adjusted incidence rates across demographic variables}}
|-
! colspan="2" style="background: #4479ba; " | {{fontcolor|#FFF| demographic variables}}
! style="background: #4479ba; " | {{fontcolor|#FFF| Rate (per 100,000)}}
|-
! rowspan="2" style="padding: 4px 4px; background: #00AF89; " | {{fontcolor|#FFF| Gender}}
! style="padding: 3px 3px; background: #B0E0E6; " | Male
! style="padding: 3px 3px; background: #E0FFFF; " | 1.1
|-
! style="padding: 3px 3px; background: #B0E0E6; " | Female
! style="padding: 3px 3px; background: #E0FFFF; " | 1.0
|-
! rowspan="3" style="padding: 4px 4px; background: #00AF89; " | {{fontcolor|#FFF| Race}}
! style="padding: 3px 3px; background: #B0E0E6; " | White
! style="padding: 3px 3px; background: #E0FFFF; " | 1.1
|-
! style="padding: 3px 3px; background: #B0E0E6; " | Black
! style="padding: 3px 3px; background: #E0FFFF; " | 0.4
|-
! style="padding: 3px 3px; background: #B0E0E6; " | Other
! style="padding: 3px 3px; background: #E0FFFF; " | 1.3
|-
! rowspan="5" style="padding: 3px 3px; background: #00AF89 " | {{fontcolor|#FFF| Age (yrs), all}}
! style="padding: 3px 3px; background: #B0E0E6; " | <20
! style="padding: 3px 3px; background: #E0FFFF; " | 0.1
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 20-39
! style="padding: 3px 3px; background: #E0FFFF; " | 0.6
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 40-49
! style="padding: 3px 3px; background: #E0FFFF; " | 1.5
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 50-64
! style="padding: 3px 3px; background: #E0FFFF; " | 2.7
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 65+
! style="padding: 3px 3px; background: #E0FFFF; " | 2.0
|-
! rowspan="5" style="padding: 3px 3px; background: #00AF89; " | {{fontcolor|#FFF| Age (yrs), Male}}
! style="padding: 3px 3px; background: #B0E0E6; " | <20
! style="padding: 3px 3px; background: #E0FFFF; " | 0
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 20-39
! style="padding: 3px 3px; background: #E0FFFF; " | 0.5
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 40-49
! style="padding: 3px 3px; background: #E0FFFF; " | 1.6
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 50-64
! style="padding: 3px 3px; background: #E0FFFF; " | 2.6
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 65+
! style="padding: 3px 3px; background: #E0FFFF; " | 2.4
|-
! rowspan="5" style="padding: 3px 3px; background: #00AF89; " | {{fontcolor|#FFF| Age (yrs), Female}}
! style="padding: 3px 3px; background: #B0E0E6; " | <20
! style="padding: 3px 3px; background: #E0FFFF; " | 0.1
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 20-39
! style="padding: 3px 3px; background: #E0FFFF; " | 0.7
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 40-49
! style="padding: 3px 3px; background: #E0FFFF; " | 1.3
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 50-64
! style="padding: 3px 3px; background: #E0FFFF; " | 2.8
|-
! style="padding: 3px 3px; background: #B0E0E6; " | 65+
! style="padding: 3px 3px; background: #E0FFFF; " | 1.7
|}
 
===Incidence===
The [[incidence]] of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals.<ref>{{Cite journal
| author = [[Doris Lin]], [[Joseph L. Hegarty]], [[Nancy J. Fischbein]] & [[Robert K. Jackler]]
| title = The prevalence of "incidental" acoustic neuroma
| journal = [[Archives of otolaryngology--head & neck surgery]]
| volume = 131
| issue = 3
| pages = 241–244
| year = 2005
| month = March
| doi = 10.1001/archotol.131.3.241
| pmid = 15781765
}}</ref><ref>{{Cite journal
| author = [[M. Tos]] & [[J. Thomsen]]
| title = Epidemiology of acoustic neuromas
| journal = [[The Journal of laryngology and otology]]
| volume = 98
| issue = 7
| pages = 685–692
| year = 1984
| month = July
| pmid = 6747450
}}</ref><ref>{{Cite journal
| author = [[M. F. Howitz]], [[C. Johansen]], [[M. Tos]], [[S. Charabi]] & [[J. H. Olsen]]
| title = Incidence of vestibular schwannoma in Denmark, 1977-1995
| journal = [[The American journal of otology]]
| volume = 21
| issue = 5
| pages = 690–694
| year = 2000
| month = September
| pmid = 10993460
}}</ref><ref>{{Cite journal
<nowiki> </nowiki><nowiki>|</nowiki> author = [[R. Y. Seedat]], [[A. J. Claassen]] & [[D. A. Mol]]
| title = Incidence and management of acoustic neuromas in South Africa
| journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]]
<nowiki> </nowiki><nowiki>|</nowiki> volume = 23
<nowiki> </nowiki><nowiki>|</nowiki> issue = 6
<nowiki> </nowiki><nowiki>|</nowiki> pages = 996–998
<nowiki> </nowiki><nowiki>|</nowiki> year = 2002
<nowiki> </nowiki><nowiki>|</nowiki> month = November
<nowiki> </nowiki><nowiki>|</nowiki> pmid = 12438869
}}</ref>
 
===Prevalence===
===Prevalence===
Acoustic neuromas are estimated to affect 1 in 100,000 people in the general population.
The [[prevalence]] of acoustic neuroma is approximately 0.2 per 100,000 individuals.<ref>{{Cite journal
===Incidence===
| author = [[Doris Lin]], [[Joseph L. Hegarty]], [[Nancy J. Fischbein]] & [[Robert K. Jackler]]
Approximately 2,500 new cases are diagnosed each year. Researchers believe that the incidence of acoustic neuroma has risen in the last several years, due to the greater frequency in which small tumors are recognized.
| title = The prevalence of "incidental" acoustic neuroma
| journal = [[Archives of otolaryngology--head & neck surgery]]
| volume = 131
| issue = 3
| pages = 241–244
| year = 2005
| month = March
| doi = 10.1001/archotol.131.3.241
| pmid = 15781765
}}</ref>
===Mortality rate===
The in-hospital [[mortality rate]] of [[surgery]] for acoustic neuroma in the United States is 0.5%.<ref name="McClellandKim2017">{{cite journal|last1=McClelland|first1=Shearwood|last2=Kim|first2=Ellen|last3=Murphy|first3=James D.|last4=Jaboin|first4=Jerry J.|title=Operative Mortality Rates of Acoustic Neuroma Surgery|journal=Otology & Neurotology|volume=38|issue=5|year=2017|pages=751–753|issn=1531-7129|doi=10.1097/MAO.0000000000001362}}</ref>
 
===Age===
* Most cases of acoustic neuroma develop in individuals between the ages of 30 and 60.
* Although quite rare, they can also develop in children.<ref>{{Cite journal
| author = [[Xiang Huang]], [[Jian Xu]], [[Ming Xu]], [[Liang-Fu Zhou]], [[Rong Zhang]], [[Liqin Lang]], [[Qiwu Xu]], [[Ping Zhong]], [[Mingyu Chen]], [[Ying Wang]] & [[Zhenyu Zhang]]
| title = Clinical features of intracranial vestibular schwannomas
| journal = [[Oncology letters]]
| volume = 5
| issue = 1
| pages = 57–62
| year = 2013
| month = January
| doi = 10.3892/ol.2012.1011
| pmid = 23255894
}}</ref>
 
===Gender===
===Gender===
Acoustic neuromas affect women more often than men. Although quite rare, they can develop in children.  
Acoustic neuroma can affect women more often than men.<ref>{{Cite journal
===Age===
| author = [[Xiang Huang]], [[Jian Xu]], [[Ming Xu]], [[Liang-Fu Zhou]], [[Rong Zhang]], [[Liqin Lang]], [[Qiwu Xu]], [[Ping Zhong]], [[Mingyu Chen]], [[Ying Wang]] & [[Zhenyu Zhang]]
Most cases of acoustic neuroma develop in individuals between the ages of 30 and 60.
  | title = Clinical features of intracranial vestibular schwannomas
| journal = [[Oncology letters]]
| volume = 5
| issue = 1
| pages = 57–62
| year = 2013
| month = January
| doi = 10.3892/ol.2012.1011
| pmid = 23255894
}}</ref>
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}
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Latest revision as of 17:59, 24 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2] Mohsen Basiri M.D.Sabawoon Mirwais, M.B.B.S, M.D.[3]

Overview

The incidence of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals. The prevalence of acoustic neuroma is approximately 0.2 per 100,000 individuals. Women are more commonly affected by acoustic neuroma than men. Most cases of acoustic neuroma develop in individuals between 30 and 60 years of age.

Epidemiology and Demographics

Acoustic neuroma accounts for 7 - 8% of all primary intracranial tumors and 75 - 90% of cerebellopontine angle masses. Bilateral vestibular schwannomas are highly suggestive of neurofibromatosis type 2 (NF2), although bilateral tumors are encountered in the familial form of acoustic schwannomas in the absence of other stigmata of NF2.[1][2][3]

Age-adjusted incidence rates across demographic variables
demographic variables Rate (per 100,000)
Gender Male 1.1
Female 1.0
Race White 1.1
Black 0.4
Other 1.3
Age (yrs), all <20 0.1
20-39 0.6
40-49 1.5
50-64 2.7
65+ 2.0
Age (yrs), Male <20 0
20-39 0.5
40-49 1.6
50-64 2.6
65+ 2.4
Age (yrs), Female <20 0.1
20-39 0.7
40-49 1.3
50-64 2.8
65+ 1.7

Incidence

The incidence of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals.[4][5][6][7]

Prevalence

The prevalence of acoustic neuroma is approximately 0.2 per 100,000 individuals.[8]

Mortality rate

The in-hospital mortality rate of surgery for acoustic neuroma in the United States is 0.5%.[9]

Age

  • Most cases of acoustic neuroma develop in individuals between the ages of 30 and 60.
  • Although quite rare, they can also develop in children.[10]

Gender

Acoustic neuroma can affect women more often than men.[11]

References

  1. Acoustic Schwannoma. Radiopedia(2015) http://radiopaedia.org/articles/acoustic-schwannoma Accessed on October 2 2015
  2. Thomas J. Gal, MD, MPH, Jennifer Shinn, PhD, and Bin Huang, PhD, Lexington, KY (2010). "Current epidemiology and management trends in acoustic neuroma". Otolaryngology–Head and Neck Surgery.
  3. Acoustic neuroma. Medline Plus(2015) https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm Accessed on October 2 2015
  4. Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)
  5. M. Tos & J. Thomsen (1984). "Epidemiology of acoustic neuromas". The Journal of laryngology and otology. 98 (7): 685–692. PMID 6747450. Unknown parameter |month= ignored (help)
  6. M. F. Howitz, C. Johansen, M. Tos, S. Charabi & J. H. Olsen (2000). "Incidence of vestibular schwannoma in Denmark, 1977-1995". The American journal of otology. 21 (5): 690–694. PMID 10993460. Unknown parameter |month= ignored (help)
  7. {{Cite journal | author = R. Y. Seedat, A. J. Claassen & D. A. Mol | title = Incidence and management of acoustic neuromas in South Africa | journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]] | volume = 23 | issue = 6 | pages = 996–998 | year = 2002 | month = November | pmid = 12438869 }}
  8. Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)
  9. McClelland, Shearwood; Kim, Ellen; Murphy, James D.; Jaboin, Jerry J. (2017). "Operative Mortality Rates of Acoustic Neuroma Surgery". Otology & Neurotology. 38 (5): 751–753. doi:10.1097/MAO.0000000000001362. ISSN 1531-7129.
  10. Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)
  11. Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)

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