Acoustic neuroma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2] Mohsen Basiri M.D.Sabawoon Mirwais, M.B.B.S.[3]

Overview

The incidence of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals. The prevalence of acoustic neuroma is approximately 0.2 per 100,000 individuals. Women are more commonly affected by acoustic neuroma than men. Most cases of acoustic neuroma develop in individuals between 30 and 60 years of age.

Epidemiology and Demographics

Acoustic neuroma accounts for 7 - 8% of all primary intracranial tumors and 75 - 90% of cerebellopontine angle masses. Bilateral vestibular schwannomas are highly suggestive of neurofibromatosis type 2 (NF2), although bilateral tumors are encountered in the familial form of acoustic schwannomas in the absence of other stigmata of NF2.[1][2][3]

Age-adjusted incidence rates across demographic variables
demographic variables Rate (per 100,000)
Gender Male 1.1
Female 1.0
Race White 1.1
Black 0.4
Other 1.3
Age (yrs), all <20 0.1
20-39 0.6
40-49 1.5
50-64 2.7
65+ 2.0
Age (yrs), Male <20 0
20-39 0.5
40-49 1.6
50-64 2.6
65+ 2.4
Age (yrs), Female <20 0.1
20-39 0.7
40-49 1.3
50-64 2.8
65+ 1.7

Incidence

The incidence of acoustic neuroma ranges from 0.3 to 1 per 100, 000 individuals.[4][5][6][7]

Prevalence

The prevalence of acoustic neuroma is approximately 0.2 per 100,000 individuals.[8]

Mortality rate

The in-hospital mortality rate of surgery for acoustic neuroma in the United States is 0.5%.[9]

Age

  • Most cases of acoustic neuroma develop in individuals between the ages of 30 and 60.
  • Although quite rare, they can also develop in children.[10]

Gender

Acoustic neuroma can affect women more often than men.[11]

References

  1. Acoustic Schwannoma. Radiopedia(2015) http://radiopaedia.org/articles/acoustic-schwannoma Accessed on October 2 2015
  2. Thomas J. Gal, MD, MPH, Jennifer Shinn, PhD, and Bin Huang, PhD, Lexington, KY (2010). "Current epidemiology and management trends in acoustic neuroma". Otolaryngology–Head and Neck Surgery.
  3. Acoustic neuroma. Medline Plus(2015) https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm Accessed on October 2 2015
  4. Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)
  5. M. Tos & J. Thomsen (1984). "Epidemiology of acoustic neuromas". The Journal of laryngology and otology. 98 (7): 685–692. PMID 6747450. Unknown parameter |month= ignored (help)
  6. M. F. Howitz, C. Johansen, M. Tos, S. Charabi & J. H. Olsen (2000). "Incidence of vestibular schwannoma in Denmark, 1977-1995". The American journal of otology. 21 (5): 690–694. PMID 10993460. Unknown parameter |month= ignored (help)
  7. {{Cite journal | author = R. Y. Seedat, A. J. Claassen & D. A. Mol | title = Incidence and management of acoustic neuromas in South Africa | journal = [[Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology]] | volume = 23 | issue = 6 | pages = 996–998 | year = 2002 | month = November | pmid = 12438869 }}
  8. Doris Lin, Joseph L. Hegarty, Nancy J. Fischbein & Robert K. Jackler (2005). "The prevalence of "incidental" acoustic neuroma". Archives of otolaryngology--head & neck surgery. 131 (3): 241–244. doi:10.1001/archotol.131.3.241. PMID 15781765. Unknown parameter |month= ignored (help)
  9. McClelland, Shearwood; Kim, Ellen; Murphy, James D.; Jaboin, Jerry J. (2017). "Operative Mortality Rates of Acoustic Neuroma Surgery". Otology & Neurotology. 38 (5): 751–753. doi:10.1097/MAO.0000000000001362. ISSN 1531-7129.
  10. Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)
  11. Xiang Huang, Jian Xu, Ming Xu, Liang-Fu Zhou, Rong Zhang, Liqin Lang, Qiwu Xu, Ping Zhong, Mingyu Chen, Ying Wang & Zhenyu Zhang (2013). "Clinical features of intracranial vestibular schwannomas". Oncology letters. 5 (1): 57–62. doi:10.3892/ol.2012.1011. PMID 23255894. Unknown parameter |month= ignored (help)

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