Appendix cancer classification: Difference between revisions
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{{CMG}}; {{AE}} {{Soroush}} | {{CMG}}; {{AE}} {{Soroush}} | ||
==Overview== | ==Overview== | ||
[[Vermiform appendix|Appendix]] [[cancer]] is [[Classification|classifie]]<nowiki/>d according to the [[Histology|histological findings]]. According to [[World Health Organization|WHO]] classification, there are four major groups of appendix cancer including [[Epithelium|epithelial]] [[Tumor|tumors]], non-epithelial tumors, secondary tumors, and [[Hyperplasia|hyperplastic]] (metaplastic) [[polyp]]<nowiki/>s. [[Carcinoid Tumor|Carcinoid]] (well differentiated endocrine neoplasm), and [[adenocarcinoma]] are two major subtypes of [[Epithelial hyperplasia|epithelial tumors]], making the majority of [[Vermiform appendix|appendix]] [[cancer]] cases. | |||
According to | |||
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==Classification== | ==Classification== | ||
*Appendix cancer may be classified according to WHO classification into 4 groups: | *[[Vermiform appendix|Appendix]] [[cancer]] may be classified according to [[WHO]] classification into 4 groups:<ref name="WHO">Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019</ref> | ||
:*Epithelial tumors | :*[[Epithelial hyperplasia|Epithelial tumors]] | ||
:*Non-epithelial tumors | :*Non-epithelial tumors | ||
:*Secondary tumors | :*Secondary tumors | ||
:*Hyperplastic (metaplastic) | :*[[Metaplasticity|Hyperplastic (metaplastic) polyps]]. | ||
*The table below summarizes the different types of appendix cancer according to the WHO classification. | *The table below summarizes the different types of appendix cancer according to the [[World Health Organization|WHO classification]]. | ||
{| style="border: 5px; font-size: 90%; margin: 5px; width: 300px" align="center" | {| style="border: 5px; font-size: 90%; margin: 5px; width: 300px" align="center" | ||
! colspan=" | ! colspan="4" style="padding: 5px 5px; background: #4479BA; font-weight: bold; text-align:center;" |{{fontcolor|#FFF|'''WHO histological classification<br>Tumors of the appendix (Adapted from WHO/IARC)<ref name="WHO"> Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019</ref>'''}} | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Epithelial tumors | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Epithelial tumors | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Non-epithelial tumors | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Secondary tumors | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Hyperplastic polyp | |||
|- | |- | ||
| | | style="padding: 5px 5px; background: #F5F5F5; text-align:left;" | | ||
*'''Adenoma''' | *'''Adenoma''' | ||
:*Tubular | :*Tubular | ||
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:*Small cell carcinoma | :*Small cell carcinoma | ||
:*Undifferentiated carcinoma | :*Undifferentiated carcinoma | ||
*'''Carcinoid (well differentiated endocrine neoplasm)''' | *'''Carcinoid (well differentiated endocrine neoplasm)''' | ||
*'''Tubular carcinoid''' | :*EC-cell, serotonin-producing neoplasm | ||
:*L-cell, glucagon-like peptide | |||
:* and PP/PYY producing tumour | |||
:*others | |||
*'''Tubular carcinoid ''' | |||
*'''Goblet cell carcinoid (mucinous carcinoid)''' | *'''Goblet cell carcinoid (mucinous carcinoid)''' | ||
*'''Mixed carcinoid-adenocarcinoma''' | *'''Mixed carcinoid-adenocarcinoma''' | ||
*'''Others''' | *'''Others''' | ||
| style="padding: 5px 5px; background: #F5F5F5; text-align:left;" | | |||
| style="padding: 5px 5px; background: # | *'''Neuroma''' | ||
*'''Lipoma''' | |||
| | *'''Leiomyoma''' | ||
*Neuroma | *'''Gastrointestinal stromal tumor''' | ||
*Lipoma | *'''Leiomyosarcoma''' | ||
*Leiomyoma | *'''Kaposi sarcoma''' | ||
*Gastrointestinal stromal tumor | *'''Others''' | ||
*Leiomyosarcoma | *'''Malignant lymphoma''' | ||
*Kaposi sarcoma | | style="padding: 5px 5px; background: #F5F5F5; text-align:left;" | | ||
*Others | | style="padding: 5px 5px; background: #F5F5F5; text-align:left;" | | ||
| style="padding: 5px 5px; background: # | |||
| style="padding: 5px 5px; background: # | |||
|} | |} | ||
==References== | |||
{{Reflist|2}} | |||
[[Category:Surgery]] | |||
[[Category:Medicine]] | |||
[[Category:Emergency medicine]] | |||
[[Category:Oncology]] | |||
[[Category:Up-To-Date]] |
Latest revision as of 18:11, 22 February 2019
Appendix cancer Microchapters |
Diagnosis |
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Treatment |
Appendix cancer classification On the Web |
American Roentgen Ray Society Images of Appendix cancer classification |
Risk calculators and risk factors for Appendix cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
Appendix cancer is classified according to the histological findings. According to WHO classification, there are four major groups of appendix cancer including epithelial tumors, non-epithelial tumors, secondary tumors, and hyperplastic (metaplastic) polyps. Carcinoid (well differentiated endocrine neoplasm), and adenocarcinoma are two major subtypes of epithelial tumors, making the majority of appendix cancer cases.
Classification
- Epithelial tumors
- Non-epithelial tumors
- Secondary tumors
- Hyperplastic (metaplastic) polyps.
- The table below summarizes the different types of appendix cancer according to the WHO classification.
WHO histological classification Tumors of the appendix (Adapted from WHO/IARC)[1] | |||
---|---|---|---|
Epithelial tumors | Non-epithelial tumors | Secondary tumors | Hyperplastic polyp |
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References
- ↑ 1.0 1.1 Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019