Diphenadione

Jump to: navigation, search
Diphenadione
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC23H16O3
Molar mass340.371 g/mol

WikiDoc Resources for Diphenadione

Articles

Most recent articles on Diphenadione

Most cited articles on Diphenadione

Review articles on Diphenadione

Articles on Diphenadione in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Diphenadione

Images of Diphenadione

Photos of Diphenadione

Podcasts & MP3s on Diphenadione

Videos on Diphenadione

Evidence Based Medicine

Cochrane Collaboration on Diphenadione

Bandolier on Diphenadione

TRIP on Diphenadione

Clinical Trials

Ongoing Trials on Diphenadione at Clinical Trials.gov

Trial results on Diphenadione

Clinical Trials on Diphenadione at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Diphenadione

NICE Guidance on Diphenadione

NHS PRODIGY Guidance

FDA on Diphenadione

CDC on Diphenadione

Books

Books on Diphenadione

News

Diphenadione in the news

Be alerted to news on Diphenadione

News trends on Diphenadione

Commentary

Blogs on Diphenadione

Definitions

Definitions of Diphenadione

Patient Resources / Community

Patient resources on Diphenadione

Discussion groups on Diphenadione

Patient Handouts on Diphenadione

Directions to Hospitals Treating Diphenadione

Risk calculators and risk factors for Diphenadione

Healthcare Provider Resources

Symptoms of Diphenadione

Causes & Risk Factors for Diphenadione

Diagnostic studies for Diphenadione

Treatment of Diphenadione

Continuing Medical Education (CME)

CME Programs on Diphenadione

International

Diphenadione en Espanol

Diphenadione en Francais

Business

Diphenadione in the Marketplace

Patents on Diphenadione

Experimental / Informatics

List of terms related to Diphenadione

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Diphenadione is a vitamin K antagonist which has anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and other rodents. This chemical compound is an anti-coagulant with longer activity than warfarin and other synthetic indandione anticoagulants.[1]

Safety and Toxicity

Diphenadione is highly toxic for human skin by all means of contact. Consumption of the drug may cause major blood clotting and irregular heartbeats.[2] An online pesticide database gives more information about the safety of diphenadione.[3] The U.S. Environmental Protection Agency has issued a safety handbook which explains how incidents of poisoning with similar rodenticides are usually treated.[4] For treatment purposes Vitamin K antagonists like diphenadione are placed under the heading of coumarins and indandiones. The handbook notes that "...as agents specifically designed to kill mammals, often their toxicity is very similar for the target rodents and for humans."[5]

References

  1. "Diphacinone". Pmep.cce.cornell.edu. Retrieved 2011-12-07.
  2. Bell Laboratories, Inc. July, 1990. Diphacinone Technical: MSDS. Bell Labs, Madison, WI.
  3. "Diphacinone - toxicity, ecological toxicity and regulatory information". Pesticideinfo.org. Retrieved 2011-12-07.
  4. Routt Reigart and James Roberts (1999). Recognition and management of pesticide poisonings (5th edition). USEPA.
  5. Reigart, page 169.

Linked-in.jpg