Phenprocoumon

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Phenprocoumon
Phenprocoumon svg.png
Clinical data
ATC code
Pharmacokinetic data
Protein binding99%
Metabolismhepatic to inactive metabolites
Elimination half-life5 to 6 days
Identifiers
CAS Number
PubChem CID
DrugBank
E number{{#property:P628}}
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Chemical and physical data
FormulaC18H16O3
Molar mass280.318 g/mol

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List of terms related to Phenprocoumon

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Phenprocoumon (marketed under the brand names Marcoumar, Marcumar and Falithrom) is a long-acting oral anticoagulant drug, a derivative of coumarin. It is a vitamin K antagonist that inhibits coagulation by blocking synthesis of coagulation factors II, VII, IX and X. It is used for the prophylaxis and treatment of thromboembolic disorders (thrombosis/pulmonary embolism). It is the standard coumarin used in Germany.

Phenprocoumon is a 4-hydroxycoumarin and inhibits vitamin K epoxide reductase.[1]

External Links

References

  1. Phenprocoumon at PharmGKB

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