Adenocarcinoma of the lung natural history, complications, and prognosis: Difference between revisions
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==Natural History== | ==Natural History== | ||
*The majority of lung cancers present with advanced disease because the symptoms tend to occur later in the course of the disease<ref> | *The majority of lung cancers present with advanced disease because the symptoms tend to occur later in the course of the disease.<ref name=leary>{{cite book | last = Leary | first = A | title = Lung cancer a multidisciplinary approach | publisher = Wiley-Blackwell | location = Chichester, West Sussex, UK Ames, Iowa | year = 2012 | isbn = 9781405180757 }}</ref> | ||
*The patient experiences non-specific symptoms such as [[cough]], [[hemoptysis]], [[dyspnea]], [[chest pain]], [[dysphonia]], [[dysphagia]], lack of appetite, [[weight loss]], and [[fatigue]] from 3 weeks to 3 months before seeking medical attention. | *The patient experiences non-specific symptoms such as [[cough]], [[hemoptysis]], [[dyspnea]], [[chest pain]], [[dysphonia]], [[dysphagia]], lack of appetite, [[weight loss]], and [[fatigue]] from 3 weeks to 3 months before seeking medical attention. | ||
*While of duration of symptoms, the [[tumor]] cell may double 20 times.<ref> | *While of duration of symptoms, the [[tumor]] cell may double 20 times.<ref name=leary>{{cite book | last = Leary | first = A | title = Lung cancer a multidisciplinary approach | publisher = Wiley-Blackwell | location = Chichester, West Sussex, UK Ames, Iowa | year = 2012 | isbn = 9781405180757 }}</ref> | ||
*In more advanced disease, the tumor may spread to other organs such as the [[spinal cord]], [[brain]], and [[bone]]. | *In more advanced disease, the tumor may spread to other organs such as the [[spinal cord]], [[brain]], and [[bone]]. | ||
*These patients may develop symptoms such as leg weakness, [[paresthesias]], bladder dysfunction, [[seizures]], [[hemiplegia]], cranial nerve palsies, [[confusion]] , personality changes, skeletal pain, and [[pleuritic]] pain.<ref> | *These patients may develop symptoms such as leg weakness, [[paresthesias]], bladder dysfunction, [[seizures]], [[hemiplegia]], cranial nerve palsies, [[confusion]] , personality changes, skeletal pain, and [[pleuritic]] pain.<ref name=leary>{{cite book | last = Leary | first = A | title = Lung cancer a multidisciplinary approach | publisher = Wiley-Blackwell | location = Chichester, West Sussex, UK Ames, Iowa | year = 2012 | isbn = 9781405180757 }}</ref> | ||
*Once the cancer spreads to the other organs, it is most likely fatal. | *Once the cancer spreads to the other organs, it is most likely fatal. | ||
Revision as of 14:16, 22 December 2015
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Adenocarcinoma of the Lung Microchapters |
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Differentiating Adenocarcinoma of the Lung from other Diseases |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Natural History
- The majority of lung cancers present with advanced disease because the symptoms tend to occur later in the course of the disease.[1]
- The patient experiences non-specific symptoms such as cough, hemoptysis, dyspnea, chest pain, dysphonia, dysphagia, lack of appetite, weight loss, and fatigue from 3 weeks to 3 months before seeking medical attention.
- While of duration of symptoms, the tumor cell may double 20 times.[1]
- In more advanced disease, the tumor may spread to other organs such as the spinal cord, brain, and bone.
- These patients may develop symptoms such as leg weakness, paresthesias, bladder dysfunction, seizures, hemiplegia, cranial nerve palsies, confusion , personality changes, skeletal pain, and pleuritic pain.[1]
- Once the cancer spreads to the other organs, it is most likely fatal.
Prognosis
Non–small cell lung cancer survival rate by stage[2]
| Stage | 5-year survival rate |
|---|---|
| IA | 49% |
| IB | 45% |
| IIA | 30% |
| IIB | 31% |
| IIIA | 14% |
| IIIB | 5% |
| IV | 1% |
References
- ↑ 1.0 1.1 1.2 Leary, A (2012). Lung cancer a multidisciplinary approach. Chichester, West Sussex, UK Ames, Iowa: Wiley-Blackwell. ISBN 9781405180757.
- ↑ Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/prognosis-and-survival/survival-statistics/?region=ab