Adenocarcinoma of the lung natural history, complications, and prognosis
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Common complications of adenocarcinoma of the lung include breathing difficulties, pneumonia, pleural effusion, metastasis, and Horner's syndrome. The prognosis of adenocarcinoma of the lung varies with the staging of tumor; stage IA have the most favorable prognosis. The presence of metastasis is associated with a particularly poor prognosis.
- The majority of lung cancers present with advanced disease because the symptoms tend to occur later in the course of the disease.
- The patient experiences non-specific symptoms such as cough, hemoptysis, dyspnea, chest pain, dysphonia, dysphagia, lack of appetite, weight loss, and fatigue from 3 weeks to 3 months before seeking medical attention.
- During the 3 weeks to 3 months course, the tumor cell may double 20 times.
- In more advanced disease, the tumor may spread to other organs such as the spinal cord, brain, and bone.
- Patients with metastasis may develop symptoms such as leg weakness, paresthesias, bladder dysfunction, seizures, hemiplegia, cranial nerve palsies, confusion, personality changes, skeletal pain, and pleuritic pain.
- Once the cancer spreads to the other organs, it is most likely to be fatal.
- Pleural effusion:
- Horner's syndrome:
- The prognosis of adenocarcinoma of the lung varies with the staging of tumor; Stage IA have the most favorable prognosis.
- The presence of metastasis is associated with a particularly poor prognosis.
Survival rate by stage
|Stage||5-year survival rate|
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- Lung cancer complications. Mayo Clinic 2015. http://www.mayoclinic.org/diseases-conditions/lung-cancer/basics/complications/con-20025531 Accessed on December 20, 2015
- Jones, DR (Jul 1998). "Pancoast tumors of the lung". Current Opinion in Pulmonary Medicine. 4 (4): 191–197. PMID 10813231.
- Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/prognosis-and-survival/survival-statistics/?region=ab