Adenocarcinoma of the lung history and symptoms: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Adenocarcinoma of the lung}} | {{Adenocarcinoma of the lung}} | ||
{{CMG}}; {{AE}} {{SC}} | {{CMG}}; {{AE}} {{SC}} {{Cherry}} | ||
==Overview== | ==Overview== | ||
The common symptoms of adenocarcinoma of the lung include [[dyspnea]], [[hemoptysis]], chronic [[coughing]], [[chest pain]], [[cachexia]], [[dysphonia]], and symptoms arising from [[paraneoplastic syndromes]] such as [[Muscle weakness|weakness]], [[Lack of coordination of muscle movement|lack of coordination]], changes in [[mental function]], high blood pressure, [[Nausea and vomiting|nausea]] and [[Nausea and vomiting|vomiting]]. | |||
==Symptoms== | ==History and Symptoms== | ||
[[ | *A positive history of smoking, family history of [[lung cancer]], [[radiation therapy]] to the chest, expsure to [[radon]] gas and [[asbestos]] is suggestive of adenocarcinoma of the [[lung]]. | ||
* [[Dyspnea]] | * The most common symptoms of adenocarcinoma of the lung include [[dyspnea]], [[hemoptysis]], chronic [[coughing]], [[Wheeze|wheezing]], [[chest pain]], [[abdominal pain]], [[cachexia]], [[fatigue]] and loss of [[appetite]].<ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on December 20, 2015</ref> | ||
===History=== | |||
Patients with adenocarcinoma of the lung may have a positive history of: | |||
* [[Smoking]] | |||
* Exposure to second-hand smoke | |||
* Family history of [[lung cancer]] | |||
* Exposure to high levels of air pollution | |||
* [[Radiation therapy]] to the chest | |||
* Expsure to [[radon]] gas | |||
* Exposure to [[asbestos]] | |||
* Exposure to high levels of [[arsenic]] in drinking water | |||
* Occupational exposure to [[Carcinogens|chemical carcinogens]] | |||
* Previous [[Respiratory disease|lung disease]] | |||
* Indoor burning of coal | |||
* [[SLE]] | |||
===Common Symptoms=== | |||
Common symptoms of adenocarcinoma of the lung include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors = Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref> | |||
*Chronic [[coughing]] | |||
*[[Dyspnea]] | |||
* [[Hemoptysis]] | * [[Hemoptysis]] | ||
* [[Wheezing]] | * [[Wheezing]] | ||
* [[Chest pain]] | * [[Chest pain]] | ||
| Line 18: | Line 36: | ||
* [[Dysphonia]] | * [[Dysphonia]] | ||
===Less Common Symptoms=== | |||
* [[Bone pain]] | Less common and late symptoms of adenocarcinoma of the lung include:<ref name="canadian" /> | ||
*[[Bone pain]] | |||
* [[Dysphagia]] | * [[Dysphagia]] | ||
* [[Superior vena cava syndrome]] | * [[Superior vena cava syndrome]] | ||
* [[Neurological | * [[Neurology|Neurological]] changes: | ||
:* [[Weakness]] | :* [[Weakness]] | ||
:* Numbness in extremities | :* Numbness in extremities | ||
| Line 28: | Line 47: | ||
:* [[Seizure]] | :* [[Seizure]] | ||
* [[Lymphadenopathy]] | * [[Lymphadenopathy]] | ||
* Symptoms due to [[Paraneoplastic syndrome|paraneoplastic syndromes]]:<ref name="canadian" /> | |||
** [[Cancer|Cancer cells]] release substances that affect the functioning of various [[Organ (anatomy)|organs]], giving rise to a group of symptoms called [[Paraneoplastic syndrome|paraneoplastic syndromes]]. | |||
* [[ | ** [[Small cell lung cancer]] is more frequently associated with [[Paraneoplastic syndrome|paraneoplastic syndromes]], as compared to [[non–small cell lung cancer]]. | ||
* [[Small cell lung cancer]] | ** [[Paraneoplastic syndrome|Paraneoplastic syndromes]] presenting with adenocarcinoma of the lung include:<ref name="pmid25114839">{{cite journal |vauthors=Kanaji N, Watanabe N, Kita N, Bandoh S, Tadokoro A, Ishii T, Dobashi H, Matsunaga T |title=Paraneoplastic syndromes associated with lung cancer |journal=World J Clin Oncol |volume=5 |issue=3 |pages=197–223 |date=August 2014 |pmid=25114839 |pmc=4127595 |doi=10.5306/wjco.v5.i3.197 |url=}}</ref><ref name="pmid20810794">{{cite journal |vauthors=Pelosof LC, Gerber DE |title=Paraneoplastic syndromes: an approach to diagnosis and treatment |journal=Mayo Clin. Proc. |volume=85 |issue=9 |pages=838–54 |date=September 2010 |pmid=20810794 |pmc=2931619 |doi=10.4065/mcp.2010.0099 |url=}}</ref> | ||
* Paraneoplastic syndromes | *** [[Hypercalcemia]] (more commonly seen in [[squamous cell lung cancer]]) | ||
*** [[Weakness]] | |||
*** [[Ataxia|Lack of coordination]] | |||
*** Changes in [[mental function]] | |||
*** High [[blood pressure]] | |||
*** [[Nausea]] | |||
*** [[Vomiting]] | |||
*** [[Hypertrophic osteoarthropathy]]: | |||
**** Increased and sometimes painful growth of some bones, especially in the fingertips | |||
**** Finger [[clubbing]] | |||
**** Pain and swelling of bones and [[Joint|joints]] | |||
==References== | ==References== | ||
Latest revision as of 14:37, 6 March 2018
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Adenocarcinoma of the Lung Microchapters |
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Differentiating Adenocarcinoma of the Lung from other Diseases |
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Adenocarcinoma of the lung history and symptoms On the Web |
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Risk calculators and risk factors for Adenocarcinoma of the lung history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Sudarshana Datta, MD [3]
Overview
The common symptoms of adenocarcinoma of the lung include dyspnea, hemoptysis, chronic coughing, chest pain, cachexia, dysphonia, and symptoms arising from paraneoplastic syndromes such as weakness, lack of coordination, changes in mental function, high blood pressure, nausea and vomiting.
History and Symptoms
- A positive history of smoking, family history of lung cancer, radiation therapy to the chest, expsure to radon gas and asbestos is suggestive of adenocarcinoma of the lung.
- The most common symptoms of adenocarcinoma of the lung include dyspnea, hemoptysis, chronic coughing, wheezing, chest pain, abdominal pain, cachexia, fatigue and loss of appetite.[1]
History
Patients with adenocarcinoma of the lung may have a positive history of:
- Smoking
- Exposure to second-hand smoke
- Family history of lung cancer
- Exposure to high levels of air pollution
- Radiation therapy to the chest
- Expsure to radon gas
- Exposure to asbestos
- Exposure to high levels of arsenic in drinking water
- Occupational exposure to chemical carcinogens
- Previous lung disease
- Indoor burning of coal
- SLE
Common Symptoms
Common symptoms of adenocarcinoma of the lung include:[2]
- Chronic coughing
- Dyspnea
- Hemoptysis
- Wheezing
- Chest pain
- Abdominal pain
- Cachexia
- Fatigue
- Loss of appetite
- Dysphonia
Less Common Symptoms
Less common and late symptoms of adenocarcinoma of the lung include:[1]
- Lymphadenopathy
- Symptoms due to paraneoplastic syndromes:[1]
- Cancer cells release substances that affect the functioning of various organs, giving rise to a group of symptoms called paraneoplastic syndromes.
- Small cell lung cancer is more frequently associated with paraneoplastic syndromes, as compared to non–small cell lung cancer.
- Paraneoplastic syndromes presenting with adenocarcinoma of the lung include:[3][4]
- Hypercalcemia (more commonly seen in squamous cell lung cancer)
- Weakness
- Lack of coordination
- Changes in mental function
- High blood pressure
- Nausea
- Vomiting
- Hypertrophic osteoarthropathy:
References
- ↑ 1.0 1.1 1.2 Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on December 20, 2015
- ↑ Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter
|coauthors=ignored (help) - ↑ Kanaji N, Watanabe N, Kita N, Bandoh S, Tadokoro A, Ishii T, Dobashi H, Matsunaga T (August 2014). "Paraneoplastic syndromes associated with lung cancer". World J Clin Oncol. 5 (3): 197–223. doi:10.5306/wjco.v5.i3.197. PMC 4127595. PMID 25114839.
- ↑ Pelosof LC, Gerber DE (September 2010). "Paraneoplastic syndromes: an approach to diagnosis and treatment". Mayo Clin. Proc. 85 (9): 838–54. doi:10.4065/mcp.2010.0099. PMC 2931619. PMID 20810794.