Stomatitis medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2], Usama Talib, BSc, MD [3]

Overview

Preventive measures and avoidance of the inciting cause is enough for the treatment of most non-infectious causes of stomatitis. Pain medications may also be required to manage the pain caused by stomatitis. Antibiotic medical therapy is the mainstay of treatment for infectious stomatitis. The medical therapy varies among different causes and types of stomatitis.

Medical Therapy

The therapy for stomatitis is governed by following principles:[1]

Criteria for Hospitalization

The patient who develops the following conditions must be institutionalized[3]

Infectious Types

Trench mouth or acute necrotizing ulcerative gingivitis

Candidal stomatitis

Herpetic stomatitis

Noma or Gangrenous stomatitis

Non-infectious Types

Denture stomatitis

Pyostomatitis vegetans

References

  1. Wade JC, Newton B, McLaren C, Flournoy N, Keeney RE, Meyers JD (1982). "Intravenous acyclovir to treat mucocutaneous herpes simplex virus infection after marrow transplantation: a double-blind trial". Ann Intern Med. 96 (3): 265–9. PMID 7036816.
  2. Rodu B, Mattingly G (1992). "Oral mucosal ulcers: diagnosis and management". J Am Dent Assoc. 123 (10): 83–6. PMID 1401597.
  3. Kolokotronis A, Doumas S (2006). "Herpes simplex virus infection, with particular reference to the progression and complications of primary herpetic gingivostomatitis". Clin Microbiol Infect. 12 (3): 202–11. doi:10.1111/j.1469-0691.2005.01336.x. PMID 16451405.
  4. King, J. D. "Nutritional and other Factors in" Trench Mouth," with Special Reference to the Nicotinic Acid Component of the Vitamin B2 Complex." Brit. dent. J. 74.6 (1943): 141-7.
  5. Atout RN, Todescan S (2013). "Managing patients with necrotizing ulcerative gingivitis". J Can Dent Assoc. 79: d46. PMID 23763733.
  6. "Acute Necrotizing Ulcerative Gingivitis (ANUG) - Dental Disorders - Merck Manuals Professional Edition". Retrieved October 25, 2016.
  7. Posavad, CM.; Wald, A.; Kuntz, S.; Huang, ML.; Selke, S.; Krantz, E.; Corey, L. (2004). "Frequent reactivation of herpes simplex virus among HIV-1-infected patients treated with highly active antiretroviral therapy". J Infect Dis. 190 (4): 693–6. doi:10.1086/422755. PMID 15272395. Unknown parameter |month= ignored (help)
  8. Thomas E (2007). "A complication of primary herpetic gingivostomatitis". Br Dent J. 203 (1): 33–4. doi:10.1038/bdj.2007.585. PMID 17632484.
  9. Meyers JD, Wade JC, Mitchell CD, Saral R, Lietman PS, Durack DT; et al. (1982). "Multicenter collaborative trial of intravenous acyclovir for treatment of mucocutaneous herpes simplex virus infection in the immunocompromised host". Am J Med. 73 (1A): 229–35. PMID 7048914.
  10. Mitchell CD, Bean B, Gentry SR, Groth KE, Boen JR, Balfour HH (1981). "Acyclovir therapy for mucocutaneous herpes simplex infections in immunocompromised patients". Lancet. 1 (8235): 1389–92. PMID 6113352.
  11. Mandell; Gouglas, Gordon; Bennett, John. Principles and Practice of Infectious Diseases. Harvard Medical School: WILEY MEDICAL. p. 383. ISBN 0-471-87643-7. Unknown parameter |firs1t= ignored (help)
  12. Arendorf TM, Walker DM (1987). "Denture stomatitis: a review". J Oral Rehabil. 14 (3): 217–27. PMID 3298586.
  13. Magliocca KR, Fitzpatrick SG (2017) Autoimmune Disease Manifestations in the Oral Cavity. Surg Pathol Clin 10 (1):57-88. DOI:10.1016/j.path.2016.11.001 PMID: 28153136
  14. Hegarty AM, Barrett AW, Scully C (2004). "Pyostomatitis vegetans". Clin Exp Dermatol. 29 (1): 1–7. PMID 14723710.

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