Nephrotoxic drugs

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Nephrotoxic drugs

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Aarti Narayan, M.B.B.S [3]

Overview

Nephrotoxic drugs are pharmacotherapies that can lead to a decline in renal function. The drug may need to be discontinued, or the dosing reduced when this happens.

Common Nephrotoxic drugs

Antibiotics

Antibacterials

  • Occurs in 10-20% patients on 7 day course
  • Results in non-oligurics; increased creatinine
  • A single dose early in septic course is usually safe

Antivirals

Antiparasitic drugs

Chemotherapy and Immunosuppressants

Heavy Metals and Poisons

AntiHyperlipidemics

Chemotherapy

Proton channel blockers

Miscellaneous Drugs

Drugs of abuse

Nephrotoxic Drugs in Alphabetical Order

References


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