Naproxen

Synonyms / Brand Names: Aleve, Anaprox, Bonyl, DL Naproxen, DL-Naproxen, Diocodal, Dysmenalgit, Ec-naprosyn, Equiproxen, Floginax, Laraflex, Laser, Mnpa, Naixan, Naprelan, Napren, Naprium, Naprius, Naprosine, Naprosyn, Naprosyne, Naproxen Sodium, Naprux, Naxen, Naxyn, Niaxan, Nycopren, Panoxen, Pranoxen, Prexan, Proxen, Proxine, Reuxen, Veradol, Xenar x

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

Geriatric Patients
Studies indicate that although total plasma concentration of Naproxen is unchanged, the unbound plasma fraction of Naproxen is increased in the elderly. Caution is advised when high doses are required and some adjustment of dosage may be required in elderly patients. As with other drugs used in the elderly, it is prudent to use the lowest effective dose.

Patients with Moderate to Severe Renal Impairment
Naproxen-containing products are not recommended for use in patients with moderate to severe and severe renal impairment (creatinine clearance < 30 mL/min).

Rheumatoid Arthritis, Osteoarthritis and Ankylosing Spondylitis

275 mg (Naproxen 250 mg with 25 mg sodium) twice daily
or 550 mg (Naproxen 500 mg with 50 mg sodium) twice daily

For more information on dosing please refer to Instructions for administration

FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information

Trial Resources
Ongoing Trials, Trial Results

Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.

Media Resources
Slides, Video, Images, MP3, Podcasts, etc.

Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.

International Resources
en Español