Denosumab

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Denosumab^?
Therapeutic monoclonal antibody
Source	Human
Target	?
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Chemical data
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Pharmacokinetic data
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Metabolism	?
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Denosumab (formerly known as AMG 162) is a human monoclonal antibody which is used to treat osteoporosis. Denosumab is designed to target RANK Ligand, a protein that acts as the primary signal to promote bone removal. In many bone loss conditions, RANK Ligand overwhelms the body's natural defense against bone destruction.

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v • d • e Human monoclonal antibodies ("-u-")
"-limu-" (immune system)	immunosuppression: Adalimumab, Atorolimumab, Gantenerumab, Golimumab, Lerdelimumab, Metelimumab, Morolimumab, Ziralimumab immune activation: Ipilimumab, Tremelimumab other: Bertilimumab
"-kinu-" (interleukin as target)	Canakinumab
"-tumu-" (cancer immunotherapy)	Adecatumumab, Anetumumab, Belimumab, Duntumumab, Iratumumab, Lexatumumab, Lucatumumab, Mapatumumab, Ofatumumab, Panitumumab, Pritumumab, Votumumab, Zalutumumab, Zanolimumab
"-osu-" (bone)	Denosumab
"-mulu-" (musculoskeletal)	Durimulumab, Durmulumab, Stamulumab
"-fungu-" (fungal)	Efungumab
"-viru-" (viral)	Exbivirumab, Libivirumab, Regavirumab, Sevirumab, Tuvirumab
"-bacu-" (bacterial)	Nebacumab, Raxibacumab