Sudden infant death syndrome natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

  • The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
  • The symptoms of (disease name) typically develop ___ years after exposure to ___.
  • If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

  • Common complications of sudden infant death syndrome (SIDS) include:[1][2]
    • Women whose infants die from sudden infant death syndrome (SIDS) are highly likely to have complications in their following pregnancies with the following:
      • Placenta previa
      • Abruptio placenta
      • Premature rupture of membranes
    • [Complication 2]
    • [Complication 3]

Prognosis

  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
  • Depending on the risk factors for recurrence, the prognosis may vary for SIDS, which include apparent life-threatening events (ALTE).[3][4][5][6]
  • History of multiple events preceding the hospital admission, and infections that are viral in nature also play a important role in determining the prognosis in SIDS victims.
  • The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
  • [Subtype of disease/malignancy] is associated with the most favorable prognosis.
  • The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.

References

  1. Smith GC, Wood AM, Pell JP, Dobbie R (2005). "Sudden infant death syndrome and complications in other pregnancies". Lancet. 366 (9503): 2107–11. doi:10.1016/S0140-6736(05)67888-9. PMID 16360787.
  2. Smith, Gordon CS; Wood, Angela M; Pell, Jill P; Dobbie, Richard (2005). "Sudden infant death syndrome and complications in other pregnancies". The Lancet. 366 (9503): 2107–2111. doi:10.1016/S0140-6736(05)67888-9. ISSN 0140-6736.
  3. Fu LY, Moon RY (2012). "Apparent life-threatening events: an update". Pediatr Rev. 33 (8): 361–8, quiz 368-9. doi:10.1542/pir.33-8-361. PMID 22855928.
  4. McGovern MC, Smith MB (2004). "Causes of apparent life threatening events in infants: a systematic review". Arch Dis Child. 89 (11): 1043–8. doi:10.1136/adc.2003.031740. PMC 1719711. PMID 15499062.
  5. Al-Kindy HA, Gélinas JF, Hatzakis G, Côté A (2009). "Risk factors for extreme events in infants hospitalized for apparent life-threatening events". J Pediatr. 154 (3): 332–7, 337.e1–2. doi:10.1016/j.jpeds.2008.08.051. PMID 18950797.
  6. Santiago-Burruchaga M, Sánchez-Etxaniz J, Benito-Fernández J, Vázquez-Cordero C, Mintegi-Raso S, Labayru-Echeverría M; et al. (2008). "Assessment and management of infants with apparent life-threatening events in the paediatric emergency department". Eur J Emerg Med. 15 (4): 203–8. doi:10.1097/MEJ.0b013e3282f4d13a. PMID 19078815.

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