Sexcord/ stromal ovarian tumors epidemiology and demographics: Difference between revisions

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===Developed Countries===
===Developed Countries===
*The incidence and mortality has gradually declined since the 1990s in most developed countries, largely including North America and Europe
*Intrestingly there has been increases in incidence and mortality rates in less developed countries with recent economic growth and lifestyle changes
*In China, this increase is obvious only among rural women rather than those in more developed urban areas


===Developing Countries===
===Developing Countries===

Revision as of 17:16, 1 April 2019

Sexcord/ stromal ovarian tumors Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Epidemiology and Demographics

Incidence

Ovarian sex cord-stromal tumors are very uncommon neoplasms that represent only 7% of all ovarian tumors[1][2]

  • The yearly adjusted incidence rate is approximately 2 per 1,000,000 women for SCSTs
Ovarian cancer incidence exhibits wide geographic variation,Reid BM, Permuth JB, Sellers TA. Epidemiology of ovarian cancer: a review. Cancer Biol Med. 2017;14(1):9–32. doi:10.20892/j.issn.2095-3941.2016.0084, http://creativecommons.org/licenses/by-nc-sa/4.0/,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365187/

Prevalence

  • The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
  • In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
  • The prevalence of [disease/malignancy] is estimated to be [number] cases annually.

Case-fatality rate/Mortality rate

  • In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
  • The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Age

The age at presentation varies depending on the subtypes of sexcord-stromal ovarian tumors:[3]

Fibromas:

  • Although they can present at any age, the mean age of occurrence is in the late forties

Thecomas:

  • They are more likely to occur in postmenopausal women

Sclerosing stromal tumor(SSTs):

  • SSTs are more likely to occur in young women
  • Approximately 80% of the reported cases are under 30 years of age
  • A few cases have been reported in premenarchal girls, although SSTs most commonly occur after menarche

Steroid cell tumors:

  • The average age of presentation is 43 years

Adult and juvenile granulosa cell tumors:

  • The incidence of adult granulosa cell tumors peaks in early postmenopausal women
  • The juvenile form occurs predominantly in children and young women (<30 years)

Race

  • Racial predilection do exist for sexcord-stromal ovarian tumors[2]
  • Racial differences in incidence and mortality within the United States are similar to the observed international variation
  • Sexcord-stromal ovarian tumors(SCSTs) have more predilection in women of Caucasian background
  • Rates are highest among Whites, intermediate for Hispanics, and lowest among Blacks, and Asian people

Region

  • The majority of [disease name] cases are reported in [geographical region].
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

Developed Countries

  • The incidence and mortality has gradually declined since the 1990s in most developed countries, largely including North America and Europe
  • Intrestingly there has been increases in incidence and mortality rates in less developed countries with recent economic growth and lifestyle changes
  • In China, this increase is obvious only among rural women rather than those in more developed urban areas

Developing Countries

References

  1. Reid BM, Permuth JB, Sellers TA (February 2017). "Epidemiology of ovarian cancer: a review". Cancer Biol Med. 14 (1): 9–32. doi:10.20892/j.issn.2095-3941.2016.0084. PMC 5365187. PMID 28443200.
  2. 2.0 2.1 Boussios S, Zarkavelis G, Seraj E, Zerdes I, Tatsi K, Pentheroudakis G (October 2016). "Non-epithelial Ovarian Cancer: Elucidating Uncommon Gynaecological Malignancies". Anticancer Res. 36 (10): 5031–5042. doi:10.21873/anticanres.11072. PMID 27798862.
  3. Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.

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