SLC26A6

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Solute carrier family 26, member 6
Identifiers
Symbols SLC26A6 ; DKFZp586E1422
External IDs Template:OMIM5 Template:MGI HomoloGene64480
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Solute carrier family 26, member 6, also known as SLC26A6, is a human gene.[1]

This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Several alternatively spliced transcript variants of this gene, encoding distinct isoforms, have been described, but the full-length nature of some of these variants has not been determined.[1]

See also

References

  1. 1.0 1.1 "Entrez Gene: SLC26A6 solute carrier family 26, member 6".

Further reading

  • Markovich D (2001). "Physiological roles and regulation of mammalian sulfate transporters". Physiol. Rev. 81 (4): 1499–533. PMID 11581495.
  • Ignatovich O, Tomlinson IM, Popov AV; et al. (2000). "Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vlambda repertoire". J. Mol. Biol. 294 (2): 457–65. doi:10.1006/jmbi.1999.3243. PMID 10610771.
  • Lohi H, Kujala M, Kerkelä E; et al. (2001). "Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger". Genomics. 70 (1): 102–12. doi:10.1006/geno.2000.6355. PMID 11087667.
  • Waldegger S, Moschen I, Ramirez A; et al. (2001). "Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family". Genomics. 72 (1): 43–50. doi:10.1006/geno.2000.6445. PMID 11247665.
  • Xie Q, Welch R, Mercado A; et al. (2002). "Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1". Am. J. Physiol. Renal Physiol. 283 (4): F826–38. doi:10.1152/ajprenal.00079.2002. PMID 12217875.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Chernova MN, Jiang L, Friedman DJ; et al. (2005). "Functional comparison of mouse slc26a6 anion exchanger with human SLC26A6 polypeptide variants: differences in anion selectivity, regulation, and electrogenicity". J. Biol. Chem. 280 (9): 8564–80. doi:10.1074/jbc.M411703200. PMID 15548529.
  • Kujala M, Tienari J, Lohi H; et al. (2006). "SLC26A6 and SLC26A7 anion exchangers have a distinct distribution in human kidney". Nephron Exp. Nephrol. 101 (2): e50–8. doi:10.1159/000086345. PMID 15956810.
  • Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
  • Shcheynikov N, Wang Y, Park M; et al. (2006). "Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6". J. Gen. Physiol. 127 (5): 511–24. doi:10.1085/jgp.200509392. PMID 16606687.
  • Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Alper SL, Stewart AK, Chernova MN; et al. (2007). "Anion exchangers in flux: functional differences between human and mouse SLC26A6 polypeptides". Novartis Found. Symp. 273: 107–19, discussion 119-25, 261–4. PMID 17120764.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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