SLC30A1

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VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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View/Edit Human

Solute carrier family 30 (zinc transporter), member 1 is a protein which in humans is encoded by the SLC30A1 gene.[1][2]

Function

SLC30A1 modulates zinc permeation through the L-type calcium channel. SLC30A1 downregulates not only Zn++ influx, but also Ca++ influx, thereby protecting cells from the effects of excessive cation permeation.[3]

See also

References

  1. Palmiter RD, Findley SD (February 1995). "Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc". The EMBO Journal. 14 (4): 639–49. PMC 398127. PMID 7882967.
  2. Seve M, Chimienti F, Devergnas S, Favier A (May 2004). "In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression". BMC Genomics. 5 (1): 32. doi:10.1186/1471-2164-5-32. PMC 428573. PMID 15154973.
  3. Segal D, Ohana E, Besser L, Hershfinkel M, Moran A, Sekler I (October 2004). "A role for ZnT-1 in regulating cellular cation influx". Biochemical and Biophysical Research Communications. 323 (4): 1145–50. doi:10.1016/j.bbrc.2004.08.211. PMID 15451416.

Further reading



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