Zinc transporter SLC39A7 (ZIP7) also known as solute carrier family 39 member 7 (SLC39A7) is a protein that in humans is encoded by the SLC39A7gene.[1][2][3]
Zinc is an essential cofactor for more than 50 classes of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. Zinc cannot passively diffuse across cell membranes and requires specific transporters, such as SLC39A7, to enter the cytosol from both the extracellular environment and from intracellular storage compartments.[3]
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Huang L, Kirschke CP, Zhang Y, Yu YY (2005). "The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus". J. Biol. Chem. 280 (15): 15456–63. doi:10.1074/jbc.M412188200. PMID15705588.
Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res. 4 (4): 1339–46. doi:10.1021/pr050048h. PMID16083285.