NFIC (gene): Difference between revisions

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{{Underlinked|date=June 2016}}
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{{DISPLAYTITLE:''NFIC'' (gene)}}
| update_page = yes
{{Infobox_gene}}
| require_manual_inspection = no
'''Nuclear factor 1 C-type''' is a [[protein]] that in humans is encoded by the ''NFIC'' [[gene]].<ref name="pmid3398920">{{cite journal | vauthors = Santoro C, Mermod N, Andrews PC, Tjian R | title = A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs | journal = Nature | volume = 334 | issue = 6179 | pages = 218–24 |date=Aug 1988 | pmid = 3398920 | pmc =  | doi = 10.1038/334218a0 }}</ref><ref name="pmid7590749">{{cite journal | vauthors = Qian F, Kruse U, Lichter P, Sippel AE | title = Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH | journal = Genomics | volume = 28 | issue = 1 | pages = 66–73 |date=Dec 1995 | pmid = 7590749 | pmc =  | doi = 10.1006/geno.1995.1107 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NFIC nuclear factor I/C (CCAAT-binding transcription factor)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4782| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Nuclear factor I/C (CCAAT-binding transcription factor)
| HGNCid = 7786
| Symbol = NFIC
| AltSymbols =; CTF; CTF5; MGC20153; NF-I; NFI
| OMIM = 600729
| ECnumber =
| Homologene = 4088
| MGIid = 109591
  | GeneAtlas_image1 = PBB_GE_NFIC_206929_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_NFIC_213298_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}}  
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006260 |text = DNA replication}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0042475 |text = odontogenesis (sensu Vertebrata)}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 4782
    | Hs_Ensembl = ENSG00000141905
    | Hs_RefseqProtein = NP_005588
    | Hs_RefseqmRNA = NM_005597
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 19
    | Hs_GenLoc_start = 3310616
    | Hs_GenLoc_end = 3414603
    | Hs_Uniprot = P08651
    | Mm_EntrezGene = 18029
    | Mm_Ensembl = ENSMUSG00000055053
    | Mm_RefseqmRNA = NM_008688
    | Mm_RefseqProtein = NP_032714
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 10
    | Mm_GenLoc_start = 80799320
    | Mm_GenLoc_end = 80830302
    | Mm_Uniprot = Q3UHA6
  }}
}}
'''Nuclear factor I/C (CCAAT-binding transcription factor)''', also known as '''NFIC''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NFIC nuclear factor I/C (CCAAT-binding transcription factor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4782| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Santoro C, Mermod N, Andrews PC, Tjian R |title=A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. |journal=Nature |volume=334 |issue= 6179 |pages= 218-24 |year= 1988 |pmid= 3398920 |doi= 10.1038/334218a0 }}
*{{cite journal   |vauthors=Blau J, Xiao H, McCracken S, etal |title=Three functional classes of transcriptional activation domain. |journal=Mol. Cell. Biol. |volume=16 |issue= 5 |pages= 2044–55 |year= 1996 |pmid= 8628270 |doi= | pmc=231191 }}
*{{cite journal  | author=Qian F, Kruse U, Lichter P, Sippel AE |title=Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH. |journal=Genomics |volume=28 |issue= 1 |pages= 66-73 |year= 1995 |pmid= 7590749 |doi= 10.1006/geno.1995.1107 }}
*{{cite journal  | vauthors=Wenzelides S, Altmann H, Wendler W, Winnacker EL |title=CTF5--a new transcriptional activator of the NFI/CTF family. |journal=Nucleic Acids Res. |volume=24 |issue= 12 |pages= 2416–21 |year= 1996 |pmid= 8710515 |doi=10.1093/nar/24.12.2416  | pmc=145930 }}
*{{cite journal  | author=Blau J, Xiao H, McCracken S, ''et al.'' |title=Three functional classes of transcriptional activation domain. |journal=Mol. Cell. Biol. |volume=16 |issue= 5 |pages= 2044-55 |year= 1996 |pmid= 8628270 |doi=  }}
*{{cite journal  | vauthors=Liu Y, Bernard HU, Apt D |title=NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing. |journal=J. Biol. Chem. |volume=272 |issue= 16 |pages= 10739–45 |year= 1997 |pmid= 9099724 |doi=10.1074/jbc.272.16.10739 }}
*{{cite journal  | author=Wenzelides S, Altmann H, Wendler W, Winnacker EL |title=CTF5--a new transcriptional activator of the NFI/CTF family. |journal=Nucleic Acids Res. |volume=24 |issue= 12 |pages= 2416-21 |year= 1996 |pmid= 8710515 |doi=  }}
*{{cite journal   |vauthors=Nogues G, Kadener S, Cramer P, etal |title=Transcriptional activators differ in their abilities to control alternative splicing. |journal=J. Biol. Chem. |volume=277 |issue= 45 |pages= 43110–4 |year= 2003 |pmid= 12221105 |doi= 10.1074/jbc.M208418200 }}
*{{cite journal  | author=Liu Y, Bernard HU, Apt D |title=NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing. |journal=J. Biol. Chem. |volume=272 |issue= 16 |pages= 10739-45 |year= 1997 |pmid= 9099724 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Nogues G, Kadener S, Cramer P, ''et al.'' |title=Transcriptional activators differ in their abilities to control alternative splicing. |journal=J. Biol. Chem. |volume=277 |issue= 45 |pages= 43110-4 |year= 2003 |pmid= 12221105 |doi= 10.1074/jbc.M208418200 }}
*{{cite journal   |vauthors=Norquay LD, Yang X, Sheppard P, etal |title=RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin. |journal=Mol. Endocrinol. |volume=17 |issue= 6 |pages= 1027–38 |year= 2003 |pmid= 12624117 |doi= 10.1210/me.2003-0025 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Wickenheisser JK, Nelson-DeGrave VL, Quinn PG, McAllister JM |title=Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1. |journal=Mol. Endocrinol. |volume=18 |issue= 3 |pages= 588–605 |year= 2004 |pmid= 14684846 |doi= 10.1210/me.2003-0090 }}
*{{cite journal | author=Norquay LD, Yang X, Sheppard P, ''et al.'' |title=RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin. |journal=Mol. Endocrinol. |volume=17 |issue= 6 |pages= 1027-38 |year= 2003 |pmid= 12624117 |doi= 10.1210/me.2003-0025 }}
*{{cite journal   |vauthors=Grimwood J, Gordon LA, Olsen A, etal |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
*{{cite journal  | author=Wickenheisser JK, Nelson-DeGrave VL, Quinn PG, McAllister JM |title=Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1. |journal=Mol. Endocrinol. |volume=18 |issue= 3 |pages= 588-605 |year= 2004 |pmid= 14684846 |doi= 10.1210/me.2003-0090 }}
*{{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 }}
*{{cite journal | author=Grimwood J, Gordon LA, Olsen A, ''et al.'' |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529-35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal   |vauthors=Zhao LH, Ba XQ, Wang XG, etal |title=BAF complex is closely related to and interacts with NF1/CTF and RNA polymerase II in gene transcriptional activation. |journal=Acta Biochim. Biophys. Sin. (Shanghai) |volume=37 |issue= 7 |pages= 440–6 |year= 2005 |pmid= 15999204 |doi=10.1111/j.1745-7270.2005.00061.x }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Zhao LH, Ba XQ, Wang XG, ''et al.'' |title=BAF complex is closely related to and interacts with NF1/CTF and RNA polymerase II in gene transcriptional activation. |journal=Acta Biochim. Biophys. Sin. (Shanghai) |volume=37 |issue= 7 |pages= 440-6 |year= 2005 |pmid= 15999204 |doi=  }}
*{{cite journal  | vauthors=Nilsson J, Bjursell G, Kannius-Janson M |title=Nuclear Jak2 and transcription factor NF1-C2: a novel mechanism of prolactin signaling in mammary epithelial cells. |journal=Mol. Cell. Biol. |volume=26 |issue= 15 |pages= 5663–74 |year= 2006 |pmid= 16847321 |doi= 10.1128/MCB.02095-05 | pmc=1592781 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | author=Nilsson J, Bjursell G, Kannius-Janson M |title=Nuclear Jak2 and transcription factor NF1-C2: a novel mechanism of prolactin signaling in mammary epithelial cells. |journal=Mol. Cell. Biol. |volume=26 |issue= 15 |pages= 5663-74 |year= 2006 |pmid= 16847321 |doi= 10.1128/MCB.02095-05 }}
*{{cite journal  | vauthors=Hebbar PB, Archer TK |title=Chromatin-dependent cooperativity between site-specific transcription factors in vivo. |journal=J. Biol. Chem. |volume=282 |issue= 11 |pages= 8284–91 |year= 2007 |pmid= 17186943 |doi= 10.1074/jbc.M610554200 | pmc=2528297 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | author=Hebbar PB, Archer TK |title=Chromatin-dependent cooperativity between site-specific transcription factors in vivo. |journal=J. Biol. Chem. |volume=282 |issue= 11 |pages= 8284-91 |year= 2007 |pmid= 17186943 |doi= 10.1074/jbc.M610554200 }}
}}
}}
{{refend}}
{{refend}}
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* {{MeshName|NFIC+protein,+human}}
* {{MeshName|NFIC+protein,+human}}


{{NLM content}}
{{Transcription factors|g1}}
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{{protein-stub}}
{{NLM content}}
{{Transcription factors}}
[[Category:Transcription factors]]
[[Category:Transcription factors]]
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{{gene-19-stub}}

Revision as of 12:52, 5 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nuclear factor 1 C-type is a protein that in humans is encoded by the NFIC gene.[1][2][3]


References

  1. ↑ Santoro C, Mermod N, Andrews PC, Tjian R (Aug 1988). "A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs". Nature. 334 (6179): 218–24. doi:10.1038/334218a0. PMID 3398920.
  2. ↑ Qian F, Kruse U, Lichter P, Sippel AE (Dec 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics. 28 (1): 66–73. doi:10.1006/geno.1995.1107. PMID 7590749.
  3. ↑ "Entrez Gene: NFIC nuclear factor I/C (CCAAT-binding transcription factor)".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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