Lung cancer history and symptoms: Difference between revisions
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{{Lung cancer}} | {{Lung cancer}} | ||
{{CMG}}; | {{CMG}}; {{AE}} {{KSH}} {{CZ}} {{SC}} | ||
==Overview== | ==Overview== | ||
Common symptoms of lung cancer include [[dyspnea|difficulty breathing]], [[hemoptysis]], [[Chronic cough|chronic coughing]], [[chest pain]], [[cachexia|weakness and wasting]], [[dysphonia|difficulty speaking]], and [[Symptom|symptoms]] related to [[paraneoplastic syndromes]]. | |||
==Symptoms== | ==History and Symptoms== | ||
=== History === | |||
*Specific areas of focus when obtaining the history are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref> | |||
:*[[Age]] | |||
:*[[Family history]] of [[cancer]] | |||
:*Personal history of [[cancer]] | |||
:*Positive history of active/[[passive smoking]] | |||
::*Number of [[Cigarette|cigarettes]]/year | |||
::*Number of years/months of [[Smoking|active smoking]] | |||
::*Number of years/months of [[Passive smoking|second-hand smoking]] | |||
::*Number of years/months since [[smoking cessation]] | |||
:*Previous primary [[infection]] of [[tuberculosis]] | |||
:*Onset of [[Lung|pulmonary]] [[Symptom|symptoms]] | |||
::*[[Acute (medicine)|Acute]] (< 6 weeks) | |||
::*[[Chronic (medical)|Chronic]] (> 6 weeks) | |||
:*Previous or current [[lung disease]], such as: | |||
::*[[Chronic obstructive pulmonary disease]] | |||
::*[[Interstitial lung disease]] | |||
*Several [[patient]] factors may influence the likelihood of a [[benign]] versus a [[malignant]] condition; these include previous exposure to [[smoke]] or other [[carcinogen]]s such as [[asbestos]], and previously [[Diagnosis|diagnosed]] [[cancer]] or [[respiratory infection]]s. | |||
*A [[patient]] with [[airway]] [[Symptom|symptoms]], especially [[hemoptysis]], is more likely to have [[cancer]] compared to a [[patient]] with no [[respiratory]] [[Symptom|symptoms]]. | |||
=== Common Symptoms === | |||
:* | *[[Symptom|Symptoms]] that suggest lung cancer include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors = Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="Buccheri2004">{{cite journal|last1=Buccheri|first1=G.|title=Lung cancer: clinical presentation and specialist referral time|journal=European Respiratory Journal|volume=24|issue=6|year=2004|pages=898–904|issn=0903-1936|doi=10.1183/09031936.04.00113603}}</ref> | ||
**[[Dyspnea|Difficulty breathing]] | |||
**[[Hemoptysis]] | |||
**[[Chronic cough|Chronic coughing]] | |||
**Non-resolving [[pneumonia]] | |||
**[[Wheezing]] | |||
**[[Chest pain]] | |||
**[[Abdominal pain]] | |||
**[[Cachexia|Weakness and wasting]] | |||
**[[Fatigue]] | |||
**[[Loss of appetite]] | |||
**[[Dysphonia|Difficulty speaking]] | |||
**[[Dysphagia|Difficulty swallowing]] | |||
=== '''Symptoms of Paraneoplastic Syndromes''' === | |||
:* | * Various [[Paraneoplastic phenomenon|paraneoplastic phenomena]] can arise in the setting of lung cancer:<ref name="Honnorat">{{cite journal | last =Honnorat | first = J | coauthors = Antoine JC | title = Paraneoplastic neurological syndromes | journal = Orphanet Journal of Rare Diseases | volume =2 | pages =22 | publisher = BioMed Central Ltd. | date = May 2007 | url=http://www.ojrd.com/content/2/1/22 | pmid =17480225 | doi=10.1186/1750-1172-2-22 | accessdate =2007-09-05 }}</ref><ref name="pmid10888708">{{cite journal| author=Kubo M, Ihn H, Yamane K, Kikuchi K, Yazawa N, Soma Y et al.| title=Serum KL-6 in adult patients with polymyositis and dermatomyositis. | journal=Rheumatology (Oxford) | year= 2000 | volume= 39 | issue= 6 | pages= 632-6 | pmid=10888708 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10888708 }} </ref> | ||
::* | |||
::* | ==== Endocrine ==== | ||
::* | |||
::* | ::*[[SIADH]] causing [[hyponatraemia]]: [[Small cell lung cancer]] | ||
::* | ::*[[ACTH]] secretion ([[Cushing syndrome]]): [[Carcinoid tumor]] and [[small cell lung cancer]] | ||
::* | ::*[[Parathyroid hormone-related protein|Parathyroid Hormone-Related Peptide (PTHrP)]] causing [[hypercalcaemia]]: [[Squamous cell carcinoma of the lung]] | ||
::* | ::*[[Carcinoid syndrome]] | ||
::* | ::*[[Gynaecomastia]] | ||
==== Neurological ==== | |||
::*[[Polyneuropathy]] | |||
::*[[Myelopathy]] | |||
::*[[Cerebellar Degeneration|Cerebellar degeneration]] | |||
::*[[Lambert-Eaton myasthenic syndrome]] | |||
==== Other ==== | |||
::*[[clubbing|Digital clubbing]] | |||
::*[[Hypertrophic pulmonary osteoarthropathy]] (HPOA): [[Squamous cell carcinoma of the lung]] | |||
::*[[Nephrotic syndrome]] | |||
::*[[Polymyositis]] | |||
::*[[Dermatomyositis]] | |||
::*[[Eosinophilia]] | |||
::*[[Acanthosis nigricans]] | |||
::*[[Thrombophlebitis]]: [[Adenocarcinoma of the lung]] | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
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{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
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[[Category:Medicine]] | |||
[[Category:Pulmonology]] | |||
[[Category:Surgery]] | |||
Latest revision as of 16:34, 5 July 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kim-Son H. Nguyen M.D. Cafer Zorkun, M.D., Ph.D. [2] Shanshan Cen, M.D. [3]
Overview
Common symptoms of lung cancer include difficulty breathing, hemoptysis, chronic coughing, chest pain, weakness and wasting, difficulty speaking, and symptoms related to paraneoplastic syndromes.
History and Symptoms
History
- Specific areas of focus when obtaining the history are outlined below:[1]
- Age
- Family history of cancer
- Personal history of cancer
- Positive history of active/passive smoking
- Number of cigarettes/year
- Number of years/months of active smoking
- Number of years/months of second-hand smoking
- Number of years/months since smoking cessation
- Previous primary infection of tuberculosis
- Onset of pulmonary symptoms
- Previous or current lung disease, such as:
- Several patient factors may influence the likelihood of a benign versus a malignant condition; these include previous exposure to smoke or other carcinogens such as asbestos, and previously diagnosed cancer or respiratory infections.
- A patient with airway symptoms, especially hemoptysis, is more likely to have cancer compared to a patient with no respiratory symptoms.
Common Symptoms
Symptoms of Paraneoplastic Syndromes
- Various paraneoplastic phenomena can arise in the setting of lung cancer:[4][5]
Endocrine
Neurological
Other
References
- ↑ Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
- ↑ Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter
|coauthors=ignored (help) - ↑ Buccheri, G. (2004). "Lung cancer: clinical presentation and specialist referral time". European Respiratory Journal. 24 (6): 898–904. doi:10.1183/09031936.04.00113603. ISSN 0903-1936.
- ↑ Honnorat, J (May 2007). "Paraneoplastic neurological syndromes". Orphanet Journal of Rare Diseases. BioMed Central Ltd. 2: 22. doi:10.1186/1750-1172-2-22. PMID 17480225. Retrieved 2007-09-05. Unknown parameter
|coauthors=ignored (help) - ↑ Kubo M, Ihn H, Yamane K, Kikuchi K, Yazawa N, Soma Y; et al. (2000). "Serum KL-6 in adult patients with polymyositis and dermatomyositis". Rheumatology (Oxford). 39 (6): 632–6. PMID 10888708.