BLZF1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Golgin-45''' is a [[protein]] that in humans is encoded by the ''BLZF1'' [[gene]].<ref name="pmid9129147">{{cite journal | vauthors = Duprez E, Tong JH, Dérré J, Chen SJ, Berger R, Chen Z, Lanotte M | title = JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia | journal = Oncogene | volume = 14 | issue = 13 | pages = 1563–70  | date = May 1997 | pmid = 9129147 | pmc =  | doi = 10.1038/sj.onc.1200995 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: BLZF1 basic leucine zipper nuclear factor 1 (JEM-1)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8548| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Basic leucine zipper nuclear factor 1 (JEM-1)
| HGNCid = 1065
| Symbol = BLZF1
| AltSymbols =; GOLGIN-45; JEM-1; JEM-1s; JEM1; MGC22497
| OMIM = 608692
| ECnumber = 
| Homologene = 31187
| MGIid = 1201607
| GeneAtlas_image1 = PBB_GE_BLZF1_210462_at_tn.png
| GeneAtlas_image2 = PBB_GE_BLZF1_32088_at_tn.png
| GeneAtlas_image3 = PBB_GE_BLZF1_203840_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
| Process = {{GNF_GO|id=GO:0001558 |text = regulation of cell growth}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006888 |text = ER to Golgi vesicle-mediated transport}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8548
    | Hs_Ensembl = ENSG00000117475
    | Hs_RefseqProtein = NP_003657
    | Hs_RefseqmRNA = NM_003666
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 167603818
    | Hs_GenLoc_end = 167632402
    | Hs_Uniprot = Q9H2G9
    | Mm_EntrezGene = 66352
    | Mm_Ensembl = ENSMUSG00000026577
    | Mm_RefseqmRNA = NM_025505
    | Mm_RefseqProtein = NP_079781
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 166126475
    | Mm_GenLoc_end = 166144159
    | Mm_Uniprot = Q3TBM0
  }}
}}
'''Basic leucine zipper nuclear factor 1 (JEM-1)''', also known as '''BLZF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: BLZF1 basic leucine zipper nuclear factor 1 (JEM-1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8548| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
BLZF1 has been shown to [[Protein-protein interaction|interact]] with [[GORASP2]].<ref name=pmid11739402>{{cite journal | vauthors = Barr FA, Preisinger C, Kopajtich R, Körner R | title = Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus | journal = J. Cell Biol. | volume = 155 | issue = 6 | pages = 885–91  | date = Dec 2001 | pmid = 11739402 | pmc = 2150891 | doi = 10.1083/jcb.200108102 }}</ref>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1-2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
| citations =
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1-2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
* {{cite journal | vauthors = Ting NS, Kao PN, Chan DW, Lintott LG, Lees-Miller SP | title = DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45 | journal = J. Biol. Chem. | volume = 273 | issue = 4 | pages = 2136–45 | year = 1998 | pmid = 9442054 | doi = 10.1074/jbc.273.4.2136 }}
*{{cite journal  | author=Duprez E, Tong JH, Dérré J, ''et al.'' |title=JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia. |journal=Oncogene |volume=14 |issue= 13 |pages= 1563-70 |year= 1997 |pmid= 9129147 |doi= 10.1038/sj.onc.1200995 }}
* {{cite journal | vauthors = Tong JH, Fant X, Duprez E, Benoit G, Uphoff CC, Drexler HG, Pla JC, Lofvenberg E, Lanotte M | title = Expression patterns of the JEM-1 gene in normal and tumor cells: ubiquity contrasting with a faint, but retinoid-induced, mRNA expression in promyelocytic NB4 cells | journal = Leukemia | volume = 12 | issue = 11 | pages = 1733–40 | year = 1998 | pmid = 9823948 | doi = 10.1038/sj.leu.2401173 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
* {{cite journal | vauthors = Tong JH, Duprez E, Lanotte M | title = JEM-1, a novel nuclear co-factor: localisation and functional interaction with AP-1 | journal = Leukemia | volume = 13 | issue = 12 | pages = 1982–92 | year = 1999 | pmid = 10602419 | doi = 10.1038/sj/leu/2401560 }}
*{{cite journal | author=Ting NS, Kao PN, Chan DW, ''et al.'' |title=DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45. |journal=J. Biol. Chem. |volume=273 |issue= 4 |pages= 2136-45 |year= 1998 |pmid= 9442054 |doi= }}
* {{cite journal | vauthors = Tong JH, Fant X, Benoit G, Chen SJ, Chen Z, Lanotte M | title = Genomic organization of the JEM-1 (BLZF1) gene on human chromosome 1q24: molecular cloning and analysis of its promoter region | journal = Genomics | volume = 69 | issue = 3 | pages = 380–90 | year = 2000 | pmid = 11056056 | doi = 10.1006/geno.2000.6347 }}
*{{cite journal | author=Tong JH, Fant X, Duprez E, ''et al.'' |title=Expression patterns of the JEM-1 gene in normal and tumor cells: ubiquity contrasting with a faint, but retinoid-induced, mRNA expression in promyelocytic NB4 cells. |journal=Leukemia |volume=12 |issue= 11 |pages= 1733-40 |year= 1998 |pmid= 9823948 |doi= }}
* {{cite journal | vauthors = Short B, Preisinger C, Körner R, Kopajtich R, Byron O, Barr FA | title = A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic | journal = J. Cell Biol. | volume = 155 | issue = 6 | pages = 877–83 | year = 2001 | pmid = 11739401 | pmc = 2150909 | doi = 10.1083/jcb.200108079 }}
*{{cite journal | author=Tong JH, Duprez E, Lanotte M |title=JEM-1, a novel nuclear co-factor: localisation and functional interaction with AP-1. |journal=Leukemia |volume=13 |issue= 12 |pages= 1982-92 |year= 2000 |pmid= 10602419 |doi= }}
* {{cite journal | vauthors = Reichman TW, Muñiz LC, Mathews MB | title = The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells | journal = Mol. Cell. Biol. | volume = 22 | issue = 1 | pages = 343–56 | year = 2002 | pmid = 11739746 | pmc = 134226 | doi = 10.1128/MCB.22.1.343-356.2002 }}
*{{cite journal | author=Tong JH, Fant X, Benoit G, ''et al.'' |title=Genomic organization of the JEM-1 (BLZF1) gene on human chromosome 1q24: molecular cloning and analysis of its promoter region. |journal=Genomics |volume=69 |issue= 3 |pages= 380-90 |year= 2001 |pmid= 11056056 |doi= 10.1006/geno.2000.6347 }}
*{{cite journal | author=Short B, Preisinger C, Körner R, ''et al.'' |title=A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic. |journal=J. Cell Biol. |volume=155 |issue= 6 |pages= 877-83 |year= 2002 |pmid= 11739401 |doi= 10.1083/jcb.200108079 }}
*{{cite journal | author=Reichman TW, Muñiz LC, Mathews MB |title=The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells. |journal=Mol. Cell. Biol. |volume=22 |issue= 1 |pages= 343-56 |year= 2002 |pmid= 11739746 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
{{refend}}
{{refend}}


== External links ==
== External links ==
* {{MeshName|BLZF1+protein,+human}}
* {{MeshName|BLZF1+protein,+human}}
* {{UCSC gene info|BLZF1}}


{{NLM content}}
{{Transcription factors|g1}}


{{protein-stub}}
{{NLM content}}
{{Transcription factors}}
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
 
{{gene-1-stub}}

Latest revision as of 02:36, 30 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

n/a

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Golgin-45 is a protein that in humans is encoded by the BLZF1 gene.[1][2]

Interactions

BLZF1 has been shown to interact with GORASP2.[3]

References

  1. ↑ Duprez E, Tong JH, Dérré J, Chen SJ, Berger R, Chen Z, Lanotte M (May 1997). "JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia". Oncogene. 14 (13): 1563–70. doi:10.1038/sj.onc.1200995. PMID 9129147.
  2. ↑ "Entrez Gene: BLZF1 basic leucine zipper nuclear factor 1 (JEM-1)".
  3. ↑ Barr FA, Preisinger C, Kopajtich R, Körner R (Dec 2001). "Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus". J. Cell Biol. 155 (6): 885–91. doi:10.1083/jcb.200108102. PMC 2150891. PMID 11739402.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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