ADCY4: Difference between revisions

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*{{cite journal  | vauthors=Gaudin C, Homcy CJ, Ishikawa Y |title=Mammalian adenylyl cyclase family members are randomly located on different chromosomes |journal=Hum. Genet. |volume=94 |issue= 5 |pages= 527–9 |year= 1994 |pmid= 7959689 |doi=10.1007/BF00211020  }}
*{{cite journal  | vauthors=Gaudin C, Homcy CJ, Ishikawa Y |title=Mammalian adenylyl cyclase family members are randomly located on different chromosomes |journal=Hum. Genet. |volume=94 |issue= 5 |pages= 527–9 |year= 1994 |pmid= 7959689 |doi=10.1007/BF00211020  }}
*{{cite journal  | vauthors=Barcova M, Speth C, Kacani L |title=Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1 |journal=Pflugers Arch. |volume=437 |issue= 4 |pages= 538–46 |year= 1999 |pmid= 10089566 |doi=10.1007/s004240050815  |display-authors=etal}}
*{{cite journal  | vauthors=Barcova M, Speth C, Kacani L |title=Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1 |journal=Pflügers Arch. |volume=437 |issue= 4 |pages= 538–46 |year= 1999 |pmid= 10089566 |doi=10.1007/s004240050815  |display-authors=etal}}
*{{cite journal  | vauthors=Speth C, Joebstl B, Barcova M, Dierich MP |title=HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones |journal=AIDS |volume=14 |issue= 6 |pages= 629–36 |year= 2000 |pmid= 10807185 |doi=10.1097/00002030-200004140-00001  }}
*{{cite journal  | vauthors=Speth C, Joebstl B, Barcova M, Dierich MP |title=HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones |journal=AIDS |volume=14 |issue= 6 |pages= 629–36 |year= 2000 |pmid= 10807185 |doi=10.1097/00002030-200004140-00001  }}
*{{cite journal  | vauthors=Patke CL, Shearer WT |title=gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression |journal=J. Allergy Clin. Immunol. |volume=105 |issue= 5 |pages= 975–82 |year= 2000 |pmid= 10808179 |doi= 10.1067/mai.2000.105315 }}
*{{cite journal  | vauthors=Patke CL, Shearer WT |title=gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression |journal=J. Allergy Clin. Immunol. |volume=105 |issue= 5 |pages= 975–82 |year= 2000 |pmid= 10808179 |doi= 10.1067/mai.2000.105315 }}

Revision as of 15:58, 29 June 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Adenylyl cyclase type 4 is an enzyme that in humans is encoded by the ADCY4 gene.[1][2]

Function

This gene encodes a member of the family of adenylyl cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylyl cyclase 4, along with adenylyl cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylyl cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.[2]

References

  1. Edelhoff S, Villacres EC, Storm DR, Disteche CM (Jul 1995). "Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse". Mamm Genome. 6 (2): 111–3. doi:10.1007/BF00303253. PMID 7766992.
  2. 2.0 2.1 "Entrez Gene: ADCY4 adenylate cyclase 4".

External links

Further reading