Riedel's thyroiditis
Riedel's thyroiditis | |
ICD-10 | E06.5 |
---|---|
ICD-9 | 245.3 |
DiseasesDB | 11590 |
eMedicine | med/2036 |
Riedel's thyroiditis, also called Riedel's struma is a chronic form of thyroiditis.
Pathophysiology
Riedel's thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule.[1] This makes the thyroid gland stone-hard and fixed to adjacent structures.
A shared mechanism with retroperitoneal fibrosis and sclerosing cholangitis has been suggested.[2]
Prevalence
Riedel's thyroiditis is classified as rare. Most patients remain euthyroid, but approximately 30% of patients become hypothyroid and very few patients are hyperthyroid. It is most seen in women.[3]
Treatment
Tamoxifen has been proposed as part of a treatment plan.[4]
Eponym
It is named for Bernhard Riedel. He first recognized the disease In 1883 and published its description in 1896.[5][6]
References
- ↑ Cho MH, Kim CS, Park JS; et al. (2007). "Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature". Endocr. J. 54 (4): 559–62. PMID 17603227. Unknown parameter
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ignored (help) - ↑ De Boer WA (1993). "Riedel's thyroiditis, retroperitoneal fibrosis, and sclerosing cholangitis: diseases with one pathogenesis?". Gut. 34 (5): 714. PMC 1374200. PMID 8504980. Unknown parameter
|month=
ignored (help) - ↑ eMedicine
- ↑ Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z (2003). "Riedel's thyroiditis treated with tamoxifen" (PDF). Croat. Med. J. 44 (2): 239–41. PMID 12698518. Unknown parameter
|month=
ignored (help) - ↑ B. M. C. L. Riedel. Die chronische, zur Bildung eisenharter Tumoren führende Entzündung der Schilddrüse. Verhandlungen der deutschen Gesellschaft für Chirurgie, 1896, 25: 101-105.
- ↑ Template:WhoNamedIt
de:Riedel-Struma
it:Tiroidite di Riedel