Respiratory failure laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of respiratory failure include abnormal bicarbonate, oxygen, phosphate, and magnesium levels. | Laboratory findings consistent with the diagnosis of respiratory failure include abnormal [[bicarbonate]], [[oxygen]], [[phosphate]], and [[magnesium]] levels. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Laboratory findings consistent with the diagnosis of respiratory failure include:<ref name="pmid28507176">{{cite journal |vauthors=O'Driscoll BR, Howard LS, Earis J, Mak V |title=BTS guideline for oxygen use in adults in healthcare and emergency settings |journal=Thorax |volume=72 |issue=Suppl 1 |pages=ii1–ii90 |date=June 2017 |pmid=28507176 |doi=10.1136/thoraxjnl-2016-209729 |url=}}</ref><ref name="pmid15219010">{{cite journal |vauthors=Celli BR, MacNee W |title=Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper |journal=Eur. Respir. J. |volume=23 |issue=6 |pages=932–46 |date=June 2004 |pmid=15219010 |doi= |url=}}</ref> | *Laboratory findings consistent with the diagnosis of respiratory failure include:<ref name="pmid28507176">{{cite journal |vauthors=O'Driscoll BR, Howard LS, Earis J, Mak V |title=BTS guideline for oxygen use in adults in healthcare and emergency settings |journal=Thorax |volume=72 |issue=Suppl 1 |pages=ii1–ii90 |date=June 2017 |pmid=28507176 |doi=10.1136/thoraxjnl-2016-209729 |url=}}</ref><ref name="pmid15219010">{{cite journal |vauthors=Celli BR, MacNee W |title=Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper |journal=Eur. Respir. J. |volume=23 |issue=6 |pages=932–46 |date=June 2004 |pmid=15219010 |doi= |url=}}</ref> | ||
**Arterial blood gases | **[[Arterial blood gas|Arterial blood gases]] | ||
***Bicarbonate may be elevated to more than 45mmHg, and oxygen levels below 60mmHg | ***[[Bicarbonate]] may be elevated to more than 45mmHg, and oxygen levels below 60mmHg | ||
**Electrolyte studies | **Electrolyte studies | ||
***Low phosphate and low magnesium | ***Low [[phosphate]] and low [[magnesium]] | ||
**Toxicology screen for detection of: | **[[Toxicology screen]] for detection of: | ||
***Opiates | ***[[Opiate|Opiates]] | ||
***Benzodiazepines | ***[[Benzodiazepine|Benzodiazepines]] | ||
***Tricyclic antidepressants | ***[[Tricyclic antidepressant|Tricyclic antidepressants]] | ||
***Barbiturates | ***[[Barbiturate|Barbiturates]] | ||
**Complete blood count | **[[Complete blood count]] | ||
***Chronic hypoxemia may be associated with polycythemia | ***[[Hypoxemia|Chronic hypoxemia]] may be associated with [[polycythemia]] | ||
***Eosinophilia may be associated with eosinophilic myalgia | ***[[Eosinophilia]] may be associated with eosinophilic myalgia | ||
**Thyroid function tests | **[[Thyroid function tests]] | ||
***An elevated TSH and decreased T4 indicates hypothyroidism | ***An elevated [[Thyroid-stimulating hormone|TSH]] and decreased [[T4]] indicates [[hypothyroidism]] | ||
**Creatine phosphokinase may be elevated and may indicate: | **[[Creatine phosphokinase]] may be elevated and may indicate: | ||
***Infectious or autoimmune polymyositis | ***Infectious or autoimmune [[polymyositis]] | ||
***Hypothyroidism | ***[[Hypothyroidism]] | ||
***Rhabdomyolysis secondary to colchicine or chloroquine toxicity | ***[[Rhabdomyolysis]] secondary to [[colchicine]] or [[chloroquine]] toxicity | ||
***Procainamide myopathy | ***[[Procainamide]] [[myopathy]] | ||
==References== | ==References== | ||
Revision as of 20:04, 19 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Laboratory findings consistent with the diagnosis of respiratory failure include abnormal bicarbonate, oxygen, phosphate, and magnesium levels.
Laboratory Findings
- Laboratory findings consistent with the diagnosis of respiratory failure include:[1][2]
- Arterial blood gases
- Bicarbonate may be elevated to more than 45mmHg, and oxygen levels below 60mmHg
- Electrolyte studies
- Toxicology screen for detection of:
- Complete blood count
- Chronic hypoxemia may be associated with polycythemia
- Eosinophilia may be associated with eosinophilic myalgia
- Thyroid function tests
- An elevated TSH and decreased T4 indicates hypothyroidism
- Creatine phosphokinase may be elevated and may indicate:
- Infectious or autoimmune polymyositis
- Hypothyroidism
- Rhabdomyolysis secondary to colchicine or chloroquine toxicity
- Procainamide myopathy
- Arterial blood gases
References
- ↑ O'Driscoll BR, Howard LS, Earis J, Mak V (June 2017). "BTS guideline for oxygen use in adults in healthcare and emergency settings". Thorax. 72 (Suppl 1): ii1–ii90. doi:10.1136/thoraxjnl-2016-209729. PMID 28507176.
- ↑ Celli BR, MacNee W (June 2004). "Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper". Eur. Respir. J. 23 (6): 932–46. PMID 15219010.