Acoustic neuroma natural history, complications & prognosis: Difference between revisions

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==Overview==
==Overview==
Common complications of acoustic neuroma include [[hearing loss]], [[facial]] [[numbness]] and [[weakness]], difficulty with balance, ringing in the [[ear]], [[hydrocephalus]] and recurrence of [[tumor]]. Due to improved surgical techniques and early [[diagnosis]], the [[morbidity]] associated with surgical removal of these lesions is reduced. Acoustic neuroma patients have a very good [[prognosis]] with minimal complications if treated.<ref>{{Cite web | title =NIH  acoustic neuroma Prognosis| url =https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm }}</ref> <ref name="pmid8072358">{{cite journal| author=Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB| title=The natural history of untreated acoustic neuromas. | journal=Laryngoscope | year= 1994 | volume= 104 | issue= 9 | pages= 1115-9 | pmid=8072358 | doi=10.1288/00005537-199409000-00011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8072358  }} </ref> <ref>{{Cite web | title =NHS choices acoustic neuroma complications| url =http://www.nhs.uk/Conditions/Acoustic-neuroma/Pages/Complications.aspx }}</ref>
If left untreated, an acoustic neuroma can block the flow of cerebrospinal fluid and cause hydrocephalus, which may lead to severe vision problems and difficulty breathing and swallowing. Acoustic neuroma patients have a very good [[prognosis]] with minimal complications if treated.<ref>{{Cite web | title =NIH  acoustic neuroma Prognosis| url =https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm }}</ref> <ref name="pmid8072358">{{cite journal| author=Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB| title=The natural history of untreated acoustic neuromas. | journal=Laryngoscope | year= 1994 | volume= 104 | issue= 9 | pages= 1115-9 | pmid=8072358 | doi=10.1288/00005537-199409000-00011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8072358  }}  
 
==Natural History==
==Natural History==
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3]. Common complications of [disease name] include [complication 1], [complication 2], and [complication 3]. Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
If left untreated, an acoustic neuroma can block the flow of cerebrospinal fluid and cause hydrocephalus, which may lead to severe vision problems and difficulty breathing and swallowing. About 50% of acoustic neuromas grow slowly (1-2 mm/year). The growth rate is more rapid (greater than 2 mm/year) in about twenty percentage of patients. In more than 30% of patients acoustic neuromas seem not to grow. Acoustic neuromas does not metastasize to other parts of the body. Acoustic neuroma does not [[metastasize]] to other parts of the body. AN may continue to grow and press on structures in the skull. Once hearing loss occurs, it does not return after surgery or radiosurgery. If treated acoustic neuroma patients have a very good prognosis with minimal complications. People with small, slow-growing tumors may not need treatment.  
 
Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary.  However, the prognosis is generally regarded as poor/good/excellent.
 
 
 
 
If left untreated about 50% of acoustic neuromas grow slowly (1-2 mm/year). The growth rate is constant for each patient, and can be predicted after 1 to 2 years of observation with serial MR scans. In approximately 20% of patients, the growth rate is more rapid (more than 2 mm/year). In more than 30% of patients acoustic neuromas seem not to grow. Acoustic neuromas does not metastasize to other parts of the body. The tumor may continue to grow and press on structures in the skull. Once hearing loss occurs, it does not return after surgery or radiosurgery. If treated acoustic neuroma patients have a very good prognosis with minimal complications if treated. People with small, slow-growing tumors may not need treatment  
With the emergence of magnetic resonance imaging([[MRI]]) with [[gadolinium]], acoustic neuroma tumors as small as 2 mm in diameter can be accurately detected. Due to improved surgical techniques and early [[diagnosis]], the morbidity associated with surgical removal of these lesions is reduced.<ref name="pmid8072358">{{cite journal| author=Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB| title=The natural history of untreated acoustic neuromas. | journal=Laryngoscope | year= 1994 | volume= 104 | issue= 9 | pages= 1115-9 | pmid=8072358 | doi=10.1288/00005537-199409000-00011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8072358  }} </ref>  In select group of patients(patients older than 65 years with acoustic neuroma): however, no treatment may be the most appropriate management.<ref name="pmid10763994">{{cite journal| author=Rosenberg SI| title=Natural history of acoustic neuromas. | journal=Laryngoscope | year= 2000 | volume= 110 | issue= 4 | pages= 497-508 | pmid=10763994 | doi=10.1097/00005537-200004000-00002 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10763994  }} </ref>


==Prognosis==
==Prognosis==
*An acoustic neuroma is not cancer. The tumor does not spread ([[metastasize]]) to other parts of the body.
*An acoustic neuroma is not cancer. The tumor does not ([[metastasize]]) to other parts of the body.
*The tumor may continue to grow and press on structures in the skull.  
*The tumor may continue to grow and press on structures in the skull.  
*Once [[hearing loss]] occurs, it does not return after surgery or [[radiosurgery]].
*Once [[hearing loss]] occurs, it does not return after surgery or [[radiosurgery]].
*People with small, slow-growing tumors may not need treatment.<ref>{{Cite web | title =NIH  acoustic neuroma Prognosis| url =https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm }}</ref>
*People with small, slow-growing tumors may not need treatment.<ref>{{Cite web | title =NIH  acoustic neuroma Prognosis| url =https://www.nlm.nih.gov/medlineplus/ency/article/000778.htm }}</ref>
*Acoustic neuroma patients have a very good prognosis with minimal complications if treated.
*Acoustic neuroma patients have a very good prognosis with minimal complications if treated.
*40%-60% of small tumors may not require treatment.  
*Forty to sixty percentage of small tumors may not require treatment.  
*A control rate of greater than 90% is found in tumors treated with focused [[radiation]].
*A control rate of greater than 90% is found in tumors treated with focused [[radiation]].
*A recurrence rate of less than 5% has been found following [[surgery]].
*A recurrence rate of less than 5% has been found following [[surgery]].
*Patients experience very good (equal) quality of life whether treatment is [[observation]], [[radiation]], or [[surgery]].
*Patients experience similar quality of life whether treatment is [[observation]], [[radiation]], or [[surgery]].
*With the emergence of magnetic resonance imaging([[MRI]]) with [[gadolinium]], acoustic neuroma tumors as small as 2 mm in diameter can be accurately detected. Due to improved surgical techniques and early [[diagnosis]], the morbidity associated with surgical removal of these lesions is reduced.<ref name="pmid8072358">{{cite journal| author=Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB| title=The natural history of untreated acoustic neuromas. | journal=Laryngoscope | year= 1994 | volume= 104 | issue= 9 | pages= 1115-9 | pmid=8072358 | doi=10.1288/00005537-199409000-00011 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8072358  }} </ref>  In select group of patients(patients older than 65 years with acoustic neuroma): however, no treatment may be the most appropriate management.<ref name="pmid10763994">{{cite journal| author=Rosenberg SI| title=Natural history of acoustic neuromas. | journal=Laryngoscope | year= 2000 | volume= 110 | issue= 4 | pages= 497-508 | pmid=10763994 | doi=10.1097/00005537-200004000-00002 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10763994  }} </ref>
 
==Complications==
==Complications==
An acoustic neuroma may cause a variety of complications, including:<ref>{{Cite web | title =NHS choices acoustic neuroma complications| url =http://www.nhs.uk/Conditions/Acoustic-neuroma/Pages/Complications.aspx }}</ref>
Complications of acoustic neuroma include:<ref>{{Cite web | title =NHS choices acoustic neuroma complications| url =http://www.nhs.uk/Conditions/Acoustic-neuroma/Pages/Complications.aspx }}</ref>
*[[Hearing loss]]
*Facial [[numbness]]
*Difficulties with balance
*Ringing in the ear
*[[Hydrocephalus]]
*[[Hydrocephalus]]
*Recurrence of tumor
*Recurrence of tumor
*[[Facial weakness]]
 
==References==
==References==



Revision as of 14:23, 2 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

If left untreated, an acoustic neuroma can block the flow of cerebrospinal fluid and cause hydrocephalus, which may lead to severe vision problems and difficulty breathing and swallowing. Acoustic neuroma patients have a very good prognosis with minimal complications if treated.[1]

  • Acoustic neuroma patients have a very good prognosis with minimal complications if treated.
  • Forty to sixty percentage of small tumors may not require treatment.
  • A control rate of greater than 90% is found in tumors treated with focused radiation.
  • A recurrence rate of less than 5% has been found following surgery.
  • Patients experience similar quality of life whether treatment is observation, radiation, or surgery.
  • With the emergence of magnetic resonance imaging(MRI) with gadolinium, acoustic neuroma tumors as small as 2 mm in diameter can be accurately detected. Due to improved surgical techniques and early diagnosis, the morbidity associated with surgical removal of these lesions is reduced.[2] In select group of patients(patients older than 65 years with acoustic neuroma): however, no treatment may be the most appropriate management.[3]

Complications

Complications of acoustic neuroma include:[4]

References

  1. "NIH acoustic neuroma Prognosis".
  2. Strasnick B, Glasscock ME, Haynes D, McMenomey SO, Minor LB (1994). "The natural history of untreated acoustic neuromas". Laryngoscope. 104 (9): 1115–9. doi:10.1288/00005537-199409000-00011. PMID 8072358.
  3. Rosenberg SI (2000). "Natural history of acoustic neuromas". Laryngoscope. 110 (4): 497–508. doi:10.1097/00005537-200004000-00002. PMID 10763994.
  4. "NHS choices acoustic neuroma complications".


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