Appendix cancer history and symptoms: Difference between revisions
No edit summary |
No edit summary |
||
Line 12: | Line 12: | ||
*Patients may complaint of vague abdominal pain or discomfort and/or girdle size changes. | *Patients may complaint of vague abdominal pain or discomfort and/or girdle size changes. | ||
*However, most of them are presenting with acute appendicitis due to obstruction of the appendix by the tumor, only after pathological studies their diagnosis is revealed. | *However, most of them are presenting with acute appendicitis due to obstruction of the appendix by the tumor, only after pathological studies their diagnosis is revealed.<ref name="pmid26648795">Kelly KJ (2015) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=26648795 Management of Appendix Cancer.] ''Clin Colon Rectal Surg'' 28 (4):247-55. [http://dx.doi.org/10.1055/s-0035-1564433 DOI:10.1055/s-0035-1564433] PMID: [https://pubmed.gov/26648795 26648795]</ref> | ||
*They may present with malignancy complications like pseudomixuma peritonei. | *They may present with malignancy complications like pseudomixuma peritonei. | ||
*Rest of the diagnosed cases are result of serendipitous finding in imaging studies or discovered during laparotomy or laparoscopy because of cancer complications. | *Rest of the diagnosed cases are result of serendipitous finding in imaging studies or discovered during laparotomy or laparoscopy because of cancer complications. | ||
*The patients complaints and presentation is influenced by the tumor histology and stage. Range from a small asymptomatic adenocarcinoma to a metastatic carcinoid tumor with liver metastasis and [[carcinoid syndrome]] signs, symptoms and complications such as diarrhea, flushing, palpitation and heart valvular problems. | *The patients complaints and presentation is influenced by the tumor histology and stage. Range from a small asymptomatic adenocarcinoma to a metastatic carcinoid tumor with liver metastasis and [[carcinoid syndrome]] signs, symptoms and complications such as diarrhea, flushing, palpitation and heart valvular problems. <ref name="WHO">Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019</ref> | ||
: | |||
===History=== | ===History=== | ||
Patients with appendix cancer may have a positive history of: | Patients with appendix cancer may have a positive history of:<ref name="WHO">Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019</ref> | ||
: | |||
*MEN1 Syndome | *MEN1 Syndome | ||
*Ulcerative colitis | *Ulcerative colitis |
Revision as of 16:50, 23 January 2019
Appendix cancer Microchapters |
Diagnosis |
---|
Treatment |
Appendix cancer history and symptoms On the Web |
American Roentgen Ray Society Images of Appendix cancer history and symptoms |
Risk calculators and risk factors for Appendix cancer history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
The majority of patients with appendix cancer are asymptomatic. Patients may complaint of vague abdominal pain or discomfort and/or girdle size changes. However, most of them are presenting with acute appendicitis due to obstruction of the appendix by tumor, or present with malignancy complications like pseudomixuma peritonei; the rest of diagnosed cases are result of serendipitous finding in imaging studies or discovered during laparotomy or laparoscopy because of cancer complications.
The patients complaints and presentation is influenced by the tumor histology and stage. Range from a small asymptomatic adenocarcinoma to a metastatic carcinoid tumor with liver metastasis and carcinoid syndrome signs, symptoms and complications.
History and Symptoms
- The majority of patients with appendix cancer are asymptomatic.
- Patients may complaint of vague abdominal pain or discomfort and/or girdle size changes.
- However, most of them are presenting with acute appendicitis due to obstruction of the appendix by the tumor, only after pathological studies their diagnosis is revealed.[1]
- They may present with malignancy complications like pseudomixuma peritonei.
- Rest of the diagnosed cases are result of serendipitous finding in imaging studies or discovered during laparotomy or laparoscopy because of cancer complications.
- The patients complaints and presentation is influenced by the tumor histology and stage. Range from a small asymptomatic adenocarcinoma to a metastatic carcinoid tumor with liver metastasis and carcinoid syndrome signs, symptoms and complications such as diarrhea, flushing, palpitation and heart valvular problems. [2]
History
Patients with appendix cancer may have a positive history of:[2]
- MEN1 Syndome
- Ulcerative colitis
- Neurofibromatosis type 1
- HNPCC
- Smoking
Common Symptoms
- Common symptoms of appendix cancer include:
- Having no symptom
- Vague Chronic abdominal pain
- Periumbilical
- Right lower quadrant
- Acute appendicitis symptoms like:
- loss of appetite
- Nausea
- Typical appendicitis abdominal pain which starts from preumblical region and move to Mcburny point
- Vomiting
- and if complicated may present with acute abdomen.
- other nonspecific symptoms of appendix cancer may include the following:
- Loss of appetite
- Nausea
- Vomiting
- Diarrhea
- Micturition
- Tenesmus
- Indigestion
- Flatulence
- Bowel irregularity
Less Common Symptoms
Around 5% of the patients with appendix carcinoid tumors develop carcinoid syndrome which presents with:
- Diarrhea
- Flushing
- Palpitation
References
- ↑ Kelly KJ (2015) Management of Appendix Cancer. Clin Colon Rectal Surg 28 (4):247-55. DOI:10.1055/s-0035-1564433 PMID: 26648795
- ↑ 2.0 2.1 Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019