Kawasaki disease history and symptoms: Difference between revisions

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== Overview ==
== Overview ==
Kawasaki disease often begins with a high and persistent [[fever]] that is not very responsive to normal doses of [[acetaminophen]] or [[ibuprofen]]. The fever may persist steadily for up to two weeks and is normally accompanied by irritability. Affected children develop red eyes, red [[mucous membrane]]s in the mouth, red cracked lips, a "[[strawberry tongue]]", iritis, keratic precipitates (detectable by an ophthalmologist but usually too small to be seen by the unaided eye), and swollen [[lymph node]]s. [[Skin rash]]es occur early in the disease, and peeling of the skin in the [[genital area]], hands, and feet (especially around the nails and on the palms and soles) may occur in later phases. Some of these symptoms may come and go during the course of the illness. If left untreated, the symptoms will eventually relent, but coronary artery aneurysms will not improve, resulting in a significant risk of death or disability due to myocardial infarction (heart attack).  If treated in a timely fashion, this risk can be mostly avoided and the course of illness cut short.
Kawasaki disease often begins with a high and persistent [[fever]] that is not very responsive to normal doses of [[acetaminophen]] or [[ibuprofen]]. The fever may persist and rise steadily for up to two weeks and is normally accompanied by irritability. Affected children develop redness of the eyes, [[Mucous membrane|mucous membranes]], and lips, a "[[strawberry tongue]]", [[iritis]], keratic precipitates (detected by an [[Ophthalmology|ophthalmologist]] but usually too small to be seen by the naked eye), and swollen [[Lymph node|lymph nodes]]. [[Skin rash]] occur early in the [[disease]], and peeling of the [[skin]] in the [[genital area]], [[Hand|hands]], and feet may occur in the later phases. Some of these [[Symptom|symptoms]] may come and go during the course of the [[illness]].  


==History and Symptoms==
==History and Symptoms==
Kawasaki disease often begins with a high and persistent [[fever]] that is not very responsive to normal doses of [[acetaminophen]] or [[ibuprofen]]. The fever may persist steadily for up to two weeks and is normally accompanied by irritability. Affected children develop red eyes, red [[mucous membrane]]s in the mouth, red cracked lips, a "[[strawberry tongue]]", iritis, keratic precipitates (detectable by an ophthalmologist but usually too small to be seen by the unaided eye), and swollen [[lymph node]]s. [[Skin rash]]es occur early in the disease, and peeling of the skin in the [[genital area]], hands, and feet (especially around the nails and on the palms and soles) may occur in later phases. Some of these symptoms may come and go during the course of the illness. If left untreated, the symptoms will eventually relent, but coronary artery aneurysms will not improve, resulting in a significant risk of death or disability due to myocardial infarction (heart attack).  If treated in a timely fashion, this risk can be mostly avoided and the course of illness cut short.<ref name="McCrindleRowley2017">{{cite journal|last1=McCrindle|first1=Brian W.|last2=Rowley|first2=Anne H.|last3=Newburger|first3=Jane W.|last4=Burns|first4=Jane C.|last5=Bolger|first5=Anne F.|last6=Gewitz|first6=Michael|last7=Baker|first7=Annette L.|last8=Jackson|first8=Mary Anne|last9=Takahashi|first9=Masato|last10=Shah|first10=Pinak B.|last11=Kobayashi|first11=Tohru|last12=Wu|first12=Mei-Hwan|last13=Saji|first13=Tsutomu T.|last14=Pahl|first14=Elfriede|title=Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association|journal=Circulation|volume=135|issue=17|year=2017|pages=e927–e999|issn=0009-7322|doi=10.1161/CIR.0000000000000484}}</ref>
[[Symptom|Symptoms]] of Kawasaki disease include a high and persistent [[fever]], skin rashes, [[desquamation]] of skin, [[irritability]], [[erythema]] of the [[Eye|eyes]], [[Lip|lips]], and [[Mucous membrane|mucous membranes]], [[strawberry tongue]], [[iritis]], keratic precipitates, and swollen [[Lymph node|lymph nodes]].<ref name="McCrindleRowley2017">{{cite journal|last1=McCrindle|first1=Brian W.|last2=Rowley|first2=Anne H.|last3=Newburger|first3=Jane W.|last4=Burns|first4=Jane C.|last5=Bolger|first5=Anne F.|last6=Gewitz|first6=Michael|last7=Baker|first7=Annette L.|last8=Jackson|first8=Mary Anne|last9=Takahashi|first9=Masato|last10=Shah|first10=Pinak B.|last11=Kobayashi|first11=Tohru|last12=Wu|first12=Mei-Hwan|last13=Saji|first13=Tsutomu T.|last14=Pahl|first14=Elfriede|title=Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association|journal=Circulation|volume=135|issue=17|year=2017|pages=e927–e999|issn=0009-7322|doi=10.1161/CIR.0000000000000484}}</ref>
===History===
[[Patient|Patients]] with Kawasaki disease may have a positive history of:
*[[Fever]] not responsive to [[acetaminophen]] or [[ibuprofen]]
===Common Symptoms===
{| align="right"
|[[File:Kawasaki tongue.jpg|300px|thumb|center| Strawberry tongue and bright red, swollen lips with vertical cracking and bleeding.<ref>By Kawasaki_symptoms.jpg: Dong Soo Kimderivative work: Natr (talk) - Kawasaki_symptoms.jpg, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=12776137</ref>]]
|}
Common [[Symptom|symptoms]] of Kawasaki disease include:
*High grade [[fever]]
**Greater than 39&nbsp;°C or 102&nbsp;°F; often as high as 40&nbsp;°C  or 104&nbsp;°F that normally lasts for more than a week if left untreated
*[[Red eye|Redness of eyes]]
*Fissuring of the lips
*[[Strawberry tongue|Red discoloration of the tongue]]
*[[Erythema|Redness]] of [[Hand|palms]] and [[Sole (foot)|soles]]
*[[Desquamation|Peeling of skin]]
*Red [[Mucous membrane|mucous membranes]]
*[[lymphadenopathy|Neck swelling]]
*[[Rash]]


 
===Less Common Symptoms===
* High-grade fever (greater than 39&nbsp;°C or 102&nbsp;°F; often as high as 40&nbsp;°C  or 104&nbsp;°F) that normally lasts for more than a week if left untreated.
Less common [[Symptom|symptoms]] of Kawasaki disease include:
* Red eyes ([[conjunctivitis]]) without pus or drainage, also known as "conjunctival injection"
*[[Uveitis|Eye redness, pain, and blurred vision]]
* Bright red, chapped, or cracked lips
*[[Tachycardia]]
* Red [[mucous membrane]]s in the mouth
*[[Nausea and vomiting|Vomiting]]
* Strawberry tongue, white coating on the tongue or prominent red bumps ([[papillae]]) on the back of the tongue
*[[Diarrhea]]
* Red palms of the hands and the soles of the feet
*[[Cough]]
* Swollen hands and feet
*[[Irritability]]
* Rash which may take many forms, but not vesicular (blister-like), on the trunk
*[[Joint pains]]  
* Swollen [[lymph node]]s (frequently only one lymph node is swollen), particularly in the neck area
*[[Anorexia]]
* Joint pain ([[arthralgia]]) and swelling, frequently symmetrical
*[[Weakness]]
* Irritability
*[[Rhinorrhea]]
* [[Tachycardia]] (rapid heart beat)
* Peeling (desquamation) palms and soles (later in the illness); peeling may begin around the nails


==References==
==References==

Latest revision as of 19:48, 14 February 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]

Overview

Kawasaki disease often begins with a high and persistent fever that is not very responsive to normal doses of acetaminophen or ibuprofen. The fever may persist and rise steadily for up to two weeks and is normally accompanied by irritability. Affected children develop redness of the eyes, mucous membranes, and lips, a "strawberry tongue", iritis, keratic precipitates (detected by an ophthalmologist but usually too small to be seen by the naked eye), and swollen lymph nodes. Skin rash occur early in the disease, and peeling of the skin in the genital area, hands, and feet may occur in the later phases. Some of these symptoms may come and go during the course of the illness.

History and Symptoms

Symptoms of Kawasaki disease include a high and persistent fever, skin rashes, desquamation of skin, irritability, erythema of the eyes, lips, and mucous membranes, strawberry tongue, iritis, keratic precipitates, and swollen lymph nodes.[1]

History

Patients with Kawasaki disease may have a positive history of:

Common Symptoms

Strawberry tongue and bright red, swollen lips with vertical cracking and bleeding.[2]

Common symptoms of Kawasaki disease include:

Less Common Symptoms

Less common symptoms of Kawasaki disease include:

References

  1. ↑ McCrindle, Brian W.; Rowley, Anne H.; Newburger, Jane W.; Burns, Jane C.; Bolger, Anne F.; Gewitz, Michael; Baker, Annette L.; Jackson, Mary Anne; Takahashi, Masato; Shah, Pinak B.; Kobayashi, Tohru; Wu, Mei-Hwan; Saji, Tsutomu T.; Pahl, Elfriede (2017). "Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association". Circulation. 135 (17): e927–e999. doi:10.1161/CIR.0000000000000484. ISSN 0009-7322.
  2. ↑ By Kawasaki_symptoms.jpg: Dong Soo Kimderivative work: Natr (talk) - Kawasaki_symptoms.jpg, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=12776137

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