Small intestine cancer risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Parminder Dhingra, M.D. [3]

Overview

Common risk factors in the development of small intestine cancer are Crohn's disease, celiac disease, radiation exposure, hereditary cancer syndromes, smoking, and alcohol.

Risk Factors

  • There are no established risk factors of small intestinal cancers.
  • However, there are some associations and most common association is Crohn's disease.
  • Other associated factors are described below.

Common risk factors

  • Crohn disease is considered to be the most important risk factor of small intestinal cancers.[1]

Less common risk factors

References

  1. Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J (August 2004). "Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients". Cancer. 101 (3): 518–26. doi:10.1002/cncr.20404. PMID 15274064.
  2. Sarosiek T, Stelmaszuk M (February 2018). "[Small intestine neoplasms]". Pol. Merkur. Lekarski (in Polish). 44 (260): 45–48. PMID 29498365.
  3. Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C. Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling? Am J Gastroenterol. 2005 Mar;100(3):703-10. PMID 15743371.

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