Sacrococcygeal teratoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

Sacrococcygeal teratoma is one of the most common congenital tumors. The incidence of sacrococcygeal teratoma, based on multiple studies conducted around the world, ranges from 3.5 - 9.3 per 100, 000 individuals. The prevalence of sacrococcygeal teratoma ranges from 1.4 - 3.3 per 100, 000 individuals. In a retrospective cohort study conducted in southern Sweden from 2000 to 2013, the overall mortality rate of sacrococcygeal teratoma was 11%. Sacrococcygeal teratoma affects neonates. There is no racial predilection to sacrococcygeal teratoma. The female to male ratio is approximately 4 to 1.

Epidemiology and Demographics

Incidence

Below given table compares different studies on the incidence of sacrococcygeal teratoma

Author Study period Country Case number Incidence
Derikx 2006[1] 1990 - 1999 The Netherlands 173 3.5/100,000
*Forrester 2006[2] 1986 - 2001 USA, Hawaii 22 4.29/100,000
*Swamy 2008[3] 1985 - 2006 England 28 3.6/100,000
*Pauniaho 2013[4] 1987 - 2008 Finland 124 9.3/100,000
*Hambraeus 2015 2000 - 2013 Sweden 19 7.1/100,000
*Included spontaneous abortions, terminations of pregnancy, and stillbirths

Prevalence

The prevalence of sacrococcygeal teratoma ranges from 1.4 - 3.3 per 100, 000 individuals.[5]

Mortality rate

In a retrospective cohort study conducted in southern Sweden from 2000 to 2013, the overall mortality rate of sacrococcygeal teratoma was 11%.[6]

Age

Race

There is no racial predilection to sacrococcygeal teratoma.

Gender

Women are more commonly affected by sacrococcygeal teratoma than men. The female to male ratio is approximately 4 to 1.[9]

References

  1. Derikx, J. P. M.; De Backer, A.; van de Schoot, L.; Aronson, D. C.; de Langen, Z. J.; van den Hoonaard, T. L.; Bax, N. M. A.; van der Staak, F.; van Heurn, L. W. E. (2006). "Factors associated with recurrence and metastasis in sacrococcygeal teratoma". British Journal of Surgery. 93 (12): 1543–1548. doi:10.1002/bjs.5379. ISSN 0007-1323.
  2. Forrester, Mathias B.; Merz, Ruth D. (2006). "Descriptive epidemiology of teratoma in infants, Hawaii, 1986-2001". Paediatric and Perinatal Epidemiology. 20 (1): 54–58. doi:10.1111/j.1365-3016.2006.00678.x. ISSN 0269-5022.
  3. Swamy, Ravi; Embleton, Nicholas; Hale, Juliet (2008). "Sacrococcygeal teratoma over two decades: Birth prevalence, prenatal diagnosis and clinical outcomes". Prenatal Diagnosis. 28 (11): 1048–1051. doi:10.1002/pd.2122. ISSN 0197-3851.
  4. Hambraeus, Mette; Arnbjörnsson, Einar; Börjesson, Anna; Salvesen, Kjell; Hagander, Lars (2016). "Sacrococcygeal teratoma: A population-based study of incidence and prenatal prognostic factors". Journal of Pediatric Surgery. 51 (3): 481–485. doi:10.1016/j.jpedsurg.2015.09.007. ISSN 0022-3468.
  5. https://rarediseases.org/
  6. Mette Hambraeus, Einar Arnbjornsson, Anna Borjesson, Kjell Salvesen & Lars Hagander (2016). "Sacrococcygeal teratoma: A population-based study of incidence and prenatal prognostic factors". Journal of pediatric surgery. 51 (3): 481–485. doi:10.1016/j.jpedsurg.2015.09.007. PMID 26454470. Unknown parameter |month= ignored (help)
  7. https://rarediseases.org/
  8. https://rarediseases.org/
  9. https://rarediseases.org/

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