Molindone

Jump to: navigation, search
Molindone
Mlindone Wiki Str.png
Clinical data
Trade namesMoban
AHFS/Drugs.comConsumer Drug Information
MedlinePlusa682238
Pregnancy
category
  • C
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
MetabolismHepatic
Elimination half-life1.5 hours
ExcretionMinor, renal and fecal
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC16H24N2O2
Molar mass276.374 g/mol
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

WikiDoc Resources for Molindone

Articles

Most recent articles on Molindone

Most cited articles on Molindone

Review articles on Molindone

Articles on Molindone in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Molindone

Images of Molindone

Photos of Molindone

Podcasts & MP3s on Molindone

Videos on Molindone

Evidence Based Medicine

Cochrane Collaboration on Molindone

Bandolier on Molindone

TRIP on Molindone

Clinical Trials

Ongoing Trials on Molindone at Clinical Trials.gov

Trial results on Molindone

Clinical Trials on Molindone at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Molindone

NICE Guidance on Molindone

NHS PRODIGY Guidance

FDA on Molindone

CDC on Molindone

Books

Books on Molindone

News

Molindone in the news

Be alerted to news on Molindone

News trends on Molindone

Commentary

Blogs on Molindone

Definitions

Definitions of Molindone

Patient Resources / Community

Patient resources on Molindone

Discussion groups on Molindone

Patient Handouts on Molindone

Directions to Hospitals Treating Molindone

Risk calculators and risk factors for Molindone

Healthcare Provider Resources

Symptoms of Molindone

Causes & Risk Factors for Molindone

Diagnostic studies for Molindone

Treatment of Molindone

Continuing Medical Education (CME)

CME Programs on Molindone

International

Molindone en Espanol

Molindone en Francais

Business

Molindone in the Marketplace

Patents on Molindone

Experimental / Informatics

List of terms related to Molindone

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Molindone (Moban) is a therapeutic antipsychotic, used in the treatment of schizophrenia.[1] It works by blocking the effects of dopamine in the brain, leading to diminished psychoses. It is rapidly absorbed when taken orally.

It is sometimes described as a typical antipsychotic,[2] and sometimes described as an atypical antipsychotic.[3]

Molindone was discontinued by its sole supplier, Endo Pharmaceuticals, on January 13, 2010. [4]

Adverse effects

The side effect profile of molindone is similar to that of other typical antipsychotics. Unlike most antipsychotics, however, molindone use is associated with weight loss.[3][5]

See also

References

  1. "molindone". F.A. Davis Company.
  2. Aparasu RR, Jano E, Johnson ML, Chen H (October 2008). "Hospitalization risk associated with typical and atypical antipsychotic use in community-dwelling elderly patients". Am J Geriatr Pharmacother. 6 (4): 198–204. doi:10.1016/j.amjopharm.2008.10.003. PMID 19028375.
  3. 3.0 3.1 Bagnall A, Fenton M, Kleijnen J, Lewis R (2007). Bagnall, Anne-Marie, ed. "Molindone for schizophrenia and severe mental illness". Cochrane Database Syst Rev (1): CD002083. doi:10.1002/14651858.CD002083.pub2. PMID 17253473.
  4. http://www.fda.gov/Drugs/DrugSafety/DrugShortages/ucm050794.htm
  5. Allison DB; Mentore JL; Heo M; et al. (1999). "Antipsychotic-induced weight gain: a comprehensive research synthesis". Am J Psychiatry. 156 (11): 1686–96. PMID 10553730. Unknown parameter |author-separator= ignored (help) Free full text

Linked-in.jpg