HLA-A80
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major histocompatibility complex (human), class I, A80
| ||
| Alleles | A*8001 | |
| Structure (See HLA-A) | ||
| Identifiers | 8001
| |
| Symbol(s) | HLA-A | |
| EBI-HLA | A*8001 | |
| Locus | chr.6 6p21.31 | |
HLA-A80 (A80) is the least common HLA-A group. The serotype identifies the more common HLA-A*8001 gene product. A80 is almost exclusively found in africa and recent immigrants groups from West Africa
Serotype
| A*80 | A80 | A10 | Sample |
| allele | % | % | size (N) |
| 8001 | 36 | 10 | 505 |
HLA-A80 typing is poor. Most typing is done with SSP-PCR. Most of 8001 are detected
with "Blank" serotype.
Distribution and References
| freq | ||||
| ref. | Population | (%) | ||
| [2] | Bamileke (Cameroon) | 1.9 | ||
| Botswana | 1.8 | |||
| [3] | Fulani (Burkino Faso) | 1.0 | ||
| [2] | Bete(Cameroon) | 0.6 | ||
| Bubi(Eq. Guinea) | 0.5 |
- ↑ derived from IMGT/HLA
- ↑ 2.0 2.1 Torimiro JN, Carr JK, Wolfe ND; et al. (2006). "HLA class I diversity among rural rainforest inhabitants in Cameroon: identification of A*2612-B*4407 haplotype". Tissue Antigens. 67 (1): 30–7. doi:10.1111/j.1399-0039.2005.00527.x. PMID 16451198.
- ↑ Modiano D, Luoni G, Petrarca V; et al. (2001). "HLA class I in three West African ethnic groups: genetic distances from sub-Saharan and Caucasoid populations". Tissue Antigens. 57 (2): 128–37. PMID 11260507.