Echinocandin

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Echinocandins are antifungal drugs that inhibit the synthesis of glucan in the cell wall, probably via the enzyme 1,3-β glucan synthase. They are fungicidal against yeast and fungistatic against mold.

References

  • Wagner C, Graninger W, Presterl E, Joukhadar C (2006). "The echinocandins: comparison of their pharmacokinetics, pharmacodynamics and clinical applications". Pharmacology. 78 (4): 161–77. PMID 17047411.
  • Morris M, Villmann M (2006). "Echinocandins in the management of invasive fungal infections, part 1". Am J Health Syst Pharm. 63 (18): 1693–703. PMID 16960253.
  • Morris M, Villmann M (2006). "Echinocandins in the management of invasive fungal infections, Part 2". Am J Health Syst Pharm. 63 (19): 1813–20. PMID 16990627.



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