De Quervain's thyroiditis history and symptoms
|
De Quervain's thyroiditis Microchapters |
|
Differentiating De Quervain's thyroiditis from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The hallmark of de Quervain's thyroiditis is hyperthyroidism with the neck pain. A positive history of viral illness and family history of de Quervain's thyroiditis are suggestive of de Quervain's thyroiditis. The most common symptoms of de Quervain's thyroiditis are neck pain, palpitations, tachycardia, nervousness, and tremors.
History and symptoms
History
Patients with de Quervain's thyroiditis usually have the history of viral illness and family history of de Quervain's thyroiditis. Patients may have the history of low-grade fever and viral flu-like symptoms, such as sore throat, myalgia, arthralgia, and malaise.
Symptoms
Common Symptoms
Common symptoms of de Quervain's thyroiditis include:[1]
- Symptoms of preceding upper respiratory infection
- Fever
- Painful thyroid swelling
- Symptoms of thyrotoxicosis
Symptoms according to the disease stage
De Quervain's thyroiditis usually causes hyperthyroidism in its acute phase. However, it can also cause hypothyroidism in some cases.[2][3][4][5]
Hyperthyroidism (in acute phase)
De Quervain's thyroiditis is usually preceded by a viral prodrome followed by the symptoms of thyrotoxicosis. This phase of thyrotoxicosis lasts for several weeks to few months.
General
The patient may have the following general symptoms:
Localized
The patient may have:
- Severe neck pain
- Radiation of pain to the ears and/or jaw
- Neck swelling
Gastrointestinal system
The patient may have:
Cardiovascular system
The patient may have:
Neuro-psychiatric system
The patient may have:
Skin and appendages
The patient may have:
Hypothyroidism (in later stage)
- The symptoms of hypothyroidism may develop in the later stages of de Quervain's thyroiditis during the recovery of thyrotoxicosis. This phase usually lasts for four to six months.
- Rarely, the residual hypothyroidism may persist.
General
The patient may have:
- Fatigue
- Lethargy
- Cold intolerance
- Myxedema
- Weight gain
- Weight loss
- Migraines
- Puffy face
Localized symptoms
The patient may have:
- Enlarged neck or presence of goiter
- Dysphonia (from involvement of the recurrent laryngeal nerve)
- Dyspnea (from the compression of the trachea)
- Dysphagia (from impingement upon the esophagus)
- Small or shrunken thyroid gland (late in the disease)
Gastrointestinal system
The patient may have:
Skin and appendages
The patient may have:
Neuro-psychiatric system
The patient may have:
- Depression
- Difficulty concentrating or thinking
- Mania
- Memory loss
- Panic attacks
Reproductive system
The patient may have:
Musculoskeletal
The patient may have:
References
- ↑ De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, Shrestha RT, Hennessey J. PMID 25905408. Missing or empty
|title=(help) - ↑ "Thyroiditis — NEJM".
- ↑ Fatourechi V, Aniszewski JP, Fatourechi GZ, Atkinson EJ, Jacobsen SJ (2003). "Clinical features and outcome of subacute thyroiditis in an incidence cohort: Olmsted County, Minnesota, study". J. Clin. Endocrinol. Metab. 88 (5): 2100–5. doi:10.1210/jc.2002-021799. PMID 12727961.
- ↑ Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
- ↑ Leibovitch G, Maaravi Y, Shalev O (1989). "Severe facial oedema and glossitis associated with mianserin". Lancet. 2 (8667): 871–2. PMID 2571803.