De Quervain's thyroiditis natural history, complications, and prognosis

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De Quervain's thyroiditis Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating De Quervain's thyroiditis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary prevention

Secondary prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

De Quervain's thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease. Complications include hypothyroidism and rarely, esophageal or tracheal compression.

Natural history, complications, and prognosis

Natural history

De Quervain's thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease.[1][2][3]

1. Prodromal stage

It includes:

2. Hyperthyroid stage

It follows the prodromal stage and includes the symptoms of thyrotoxicosis such as:

3. Euthyroid stage

Thyrotoxic stage is followed by a 1–3-week period of euthyroid phase.

4. Hypothyroid stage

The transient hypothyroid stage lasts for 6-12 months.

  • Rarely, the hypothyroid stage may persist for a longer duration.

Complications

Complications that can develop as a result of de Quervain's thyroiditis are:[1][2][3]

Prognosis

Prognosis of de Quervain's thyroiditis is usually good.

References

  1. 1.0 1.1 "Thyroiditis — NEJM".
  2. 2.0 2.1 Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
  3. 3.0 3.1 Leibovitch G, Maaravi Y, Shalev O (1989). "Severe facial oedema and glossitis associated with mianserin". Lancet. 2 (8667): 871–2. PMID 2571803.