Schistosomiasis natural history, complications and prognosis: Difference between revisions

	Schistosomiasis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Schistosomiasis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Schistosomiasis natural history, complications and prognosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Schistosomiasis natural history, complications and prognosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Schistosomiasis natural history, complications and prognosis
CDC on Schistosomiasis natural history, complications and prognosis
Schistosomiasis natural history, complications and prognosis in the news
Blogs on Schistosomiasis natural history, complications and prognosis
Directions to Hospitals Treating Schistosomiasis
Risk calculators and risk factors for Schistosomiasis natural history, complications and prognosis

VisualWikitext

Revision as of 17:03, 10 August 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Natural History

If left untreated, most of the patients with schistosomiasis may progress to develop ulceration or cancer of the bladder, liver or kidney failure.

Complications

Common complications of schistosomiasis include:

Prognosis

Depending on the extent of the disease progression at the time of diagnosis, the prognosis of schistosomiasis may vary. However, the prognosis is generally regarded as good with treatment.
The 1-year mortality rate of patients with schistosomiasis ranges approximately 0.1-11% depending upon underlying complications.
If symptoms of schistosomiasis persisting after 2 rounds of praziquantel treatment, more urine or stool samples should be taken and tested for viable parasite eggs, and re-treatment must be given if persistent infection is detected.

References

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Schistosomiasis}}
-{{CMG}}
+{{CMG}} ; {{AE}} {{ADG}}
 ==Overview==
-Above all, schistosomiasis is a [[chronic disease]].  Pathology of  ''S. mansoni'' and  ''S. japonicum'' schistosomiasis includes: [[Katayama fever]], hepatic perisinusoidal egg [[granulomas]], Symmers’ pipe stem periportal fibrosis, [[portal hypertension]], and occasional [[embolism|embolic]] egg granulomas in [[brain]] or [[spinal cord]].  Pathology of  ''S. haematobium'' schistosomiasis includes: [[hematuria]], [[scar]]ring, [[calcification]], [[squamous cell carcinoma]], and occasional embolic egg granulomas in brain or spinal cord.  [[Bladder cancer]] diagnosis and mortality are generally elevated in affected areas.
+==Natural History==
+If left untreated, most of the patients with schistosomiasis may progress to develop ulceration or cancer of the bladder, liver or kidney failure.
+==Complications==
+Common complications of schistosomiasis include:
+*[[Hematuria]]
+*[[Malnutrition]]
+*[[Growth retardation]]
+*[[[Anemia of chronic disease]]
+*[[Cervicitis]]
+*Iron-deficiency anemia
+*[[Splenomegaly]]
+*[[Intestinal polyps]]
+*[[Hydronephrosis]]
+*[[Glomerulonephritis]]
+*[[Recurrent Salmonella bacteremia]]
+*[[Bladder polyps]]
+*[[Bladder cancer]]
+*[[Infertility]]
+*[[Ectopic pregnancy]]
+*[[Portal hypertension]]
+*[[Esophageal varices]]
+*[[Ascites]]
+*[[Intestinal obstruction]]
+*[[Obstructive uropathy]]
+*[[Renal failure]]
+*[[Generalized seizures]]
+*[[Spinal cord compression]]
+*[[Cor pulmonale]]
-==Natural History and Complications==
+==Prognosis==
-Occasionally [[central nervous system]] lesions occur: cerebral granulomatous disease may be caused by ectopic ''S. japonicum'' eggs in the [[brain]], and granulomatous lesions around ectopic eggs in the [[spinal cord]] from ''S. mansoni'' and ''S. haematobium'' infections may result in a transverse [[myelitis]] with flaccid [[paraplegia]].  Continuing infection may cause granulomatous reactions and [[fibrosis]] in the affected organs, which may result in manifestations that include:
+*Depending on the extent of the disease progression at the time of diagnosis, the prognosis of schistosomiasis may vary. However, the prognosis is generally regarded as good with treatment.
+*The 1-year mortality rate of patients with schistosomiasis ranges approximately 0.1-11% depending upon underlying complications.
-* Colonic [[polyposis]] with bloody diarrhea (''Schistosoma mansoni'' mostly);
+*If symptoms of schistosomiasis persisting after 2 rounds of praziquantel treatment, more urine or stool samples should be taken and tested for viable parasite eggs, and re-treatment must be given if persistent infection is detected.
-* [[Portal hypertension]] with [[hematemesis]] and [[splenomegaly]] (''S. mansoni'', ''S. japonicum'');
-* [[Cystitis]] and ureteritis (''S. haematobium'') with [[hematuria]], which can progress to [[bladder cancer]];
-* [[Pulmonary hypertension]] (''S. mansoni'', ''S. japonicum'', more rarely ''S. haematobium'');
-* [[Glomerulonephritis]]; and central nervous system lesions.
-==Prognosis==
-Treatment before significant damage or severe complications occur usually produces good results.
 ==References==