Schistosomiasis other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

There are several other methods that can be used in the diagnosis of schistosomiasis such as formalin-ethyl acetate sedimentation, urine testing for schistososme eggs, schistosomal antigen testing, serologic testing, tissue biopsy, PCR etc.

Other diagnostic studies

Formalin-ethyl acetate sedimentation

Urine testing for schistosome eggs

Schistosomal antigen testing (urine or serum)

  • Urine sample is taken for measurement of circulating cathodic antigen released by schistosomes or serum sample for measurement of both circulating cathodic and anodic antigen.[1]
  • Identifies active infection rather than past infection.
  • May not be sufficiently sensitive for detection of low-intensity infection.

Serologic testing

Biopsy of tissue

PCR to detect schistosomal DNA

References

  1. van Etten L, Folman CC, Eggelte TA, Kremsner PG, Deelder AM (1994). "Rapid diagnosis of schistosomiasis by antigen detection in urine with a reagent strip". J. Clin. Microbiol. 32 (10): 2404–6. PMC 264074. PMID 7814474.

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