Cervicitis
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| Cervicitis Classification and external resources | |
| ICD-9 | 098.15, 099.53, 616.0 |
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Inflammation of the tissues of the cervix is known as cervicitis. Cervicitis in women has many features in common with urethritis in men and many of the causes are sexually transmitted.
Causes
Cervicitis can be caused by any of a number of infections, of which the commonest are chlamydia and gonorrhea. Trichomonas vaginalis and herpes simplex are less common causes of cervicitis. The role of Mycoplasma genitalium and bacterial vaginosis in causing cervicitis is still under investigation.[1]
Mucopurulent cervicitis
Mucopurulent cervicitis (MPC) is characterized by a purulent or mucopurulent endocervical exudate visible in the endocervical canal or in an endocervical swab specimen. Some specialists also diagnose MPC on the basis of easily induced cervical bleeding. Although some specialists consider an increased number of polymorphonuclear leukocytes on endocervical Gram stain as being useful in the diagnosis of MPC, this criterion has not been standardized, has a low positive-predictive value (PPV), and is not available in some settings. MPC often is asymptomatic, but some women have an abnormal vaginal discharge and vaginal bleeding (e.g., after sexual intercourse). MPC can be caused by C. trachomatis or N. gonorrheae; however, in most cases neither organism can be isolated. MPC can persist despite repeated courses of antimicrobial therapy. Because relapse or reinfection with C. trachomatis or N. gonorrhoeae usually does not occur in persons with persistent cases of MPC, other non-microbiologic determinants (e.g., inflammation in the zone of ectopy) might be involved.
Patients who have MPC should be tested for C. trachomatis and for N. gonorrhoeae with the most sensitive and specific test available. However, MPC is not a sensitive predictor of infection with these organisms; most women who have C. trachomatis or N. gonorrhoeae do not have MPC.
References
Additional Resources
- Centers for Disease Control and Prevention. Diseases characterized by urethritis and cervicitis. Sexually transmitted diseases treatment guidelines. MMWR Recomm Rep 2002 10 May; 51 (RR-6):30-42.
- Much of an earlier version of this article was taken from the public domain document "Diseases characterized by urethritis and cervicitis. Sexually transmitted diseases treatment guidelines 2002." which can be found at http://www.guideline.gov/summary/summary.aspx?doc_id=3236
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
