Glycoprotein IIb/IIIa

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In medicine, glycoprotein IIb/IIIa, also gpIIb/IIIa, is an integrin found on platelets. Calcium-dependent association of gpIIb and gpIIIa is required for normal platelet aggregation and endothelial adherence.

Pathology

Its absence causes Glanzmann's thrombasthenia.

See also

• Glycoprotein IIb/IIIa inhibitors

External links

• Glycoproteins+IIb-IIIa at the US National Library of Medicine Medical Subject Headings (MeSH)

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